DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32333 and YDL109C

DIOPT Version :9

Sequence 1:	NP_001261246.1	Gene:	CG32333 / 38142	FlyBaseID:	FBgn0052333	Length:	1499	Species:	Drosophila melanogaster
Sequence 2:	NP_010174.1	Gene:	YDL109C / 851449	SGDID:	S000002267	Length:	647	Species:	Saccharomyces cerevisiae

Alignment Length:	269	Identity:	62/269 - (23%)
Similarity:	98/269 - (36%)	Gaps:	93/269 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly  1232 HLVICVHGLDGN-SADLRLVRTYLELGLPGVNLEFLMSERNQGDTFSDFDTMTDRLVTEILYHID 1295
            ||||..||...| |||                :|:||.|..:    :..:...:|||.: .|..:
Yeast   194 HLVILTHGFQSNVSAD----------------MEYLMEEIYK----AQMNNPNERLVIK-GYMKN 237

  Fly  1296 SCAL----------------------NPARISFVAHSLGTIIVRSALAR---------PQMRPLL 1329
            :|..                      :..:|||:.||||.:....|:..         .::.|:
Yeast   238 ACETEKGIKFLGVGLANYIIDELYDDSVGKISFIGHSLGGLTQTFAICYIKTKYPYFFKKVEPI- 301

  Fly  1330 PRLHTFLSLSGPHLGTLYNTSGLVNMGMWFMQKWKKSGSLL-----QLCMRDTTDMRNSFLYRLS 1389
                .|:||:.|.||...:|...|.|.:        |..::     :|.::|........||.||
Yeast   302 ----NFISLASPLLGIATSTPNYVKMSL--------SMGIIGTTGQELGLKDGNYGDKPLLYLLS 354

  Fly  1390 QR---STLHHFK-NILLCGSSQDRYVPAHSARLELCKAAMRDSSSLGTIYREMVHNI----IAPI 1446
            :.   |.|..|| ..|...:..|..||.:|            ||.|...|.:::..:    .||.
Yeast   355 EESLISVLARFKRRTLYANAVNDGIVPLYS------------SSLLFLDYSQLLQKLGGQTTAPC 407

  Fly  1447 --LARPELT 1453
              |.:||::
Yeast   408 DPLFQPEVS 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32333	NP_001261246.1	DUF3657	150..226	CDD:289180
		MhpC	1223..>1447	CDD:223669	59/261 (23%)
		DUF676	1227..1422	CDD:282860	53/230 (23%)
YDL109C	NP_010174.1	DUF676	189..387	CDD:309968	54/238 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341325
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930