DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32333 and ZW18

DIOPT Version :9

Sequence 1:	NP_001261246.1	Gene:	CG32333 / 38142	FlyBaseID:	FBgn0052333	Length:	1499	Species:	Drosophila melanogaster
Sequence 2:	NP_001117514.1	Gene:	ZW18 / 842204	AraportID:	AT1G58350	Length:	794	Species:	Arabidopsis thaliana

Alignment Length:	451	Identity:	146/451 - (32%)
Similarity:	219/451 - (48%)	Gaps:	65/451 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly  1076 IYESLRPISTPAIFSNKPVLKSHSLAELKRPQNLPNHSINHHCKTHAINANGNVLENGLDHE--- 1137
            |.|.||.|.|....:...:...:|..|      :|:|.||.. .|..:|.:.:...:|:.:|
plant   365 ILEYLRDIWTKDRRAEWSIWMVYSKVE------MPHHFINSG-MTDILNQSAHKRASGVLNEPAQ 422

  Fly  1138 ----QDEIKENSNGQVRTNKQGHGSNTNSKHKRKGQLASAVQEA-----PPSISLLEFEKYREEF 1193
                :.|:...|..|:|.|.:                  ::|:.     |..:.::..|:.....
plant   423 IAATRAELHRRSIAQMRINNR------------------SIQDMHILGDPMRVPIVIIERVLNAP 469

  Fly  1194 RKQIKYQGSIYSDYVQLASELPYFYISDEYRAF-------SPNGMHLVICVHGLDGNSADLRLVR 1251
            |:.:  ..:.|..::.|..........||....       |...:.:|:.|||..|:..||||||
plant   470 RRTL--SDNSYLRHMDLLDSSLLNGHKDEAEKTKVTNSQQSARELKIVVFVHGFQGHHLDLRLVR 532

  Fly  1252 TYLELGLPGVNLEFLMSERNQGDTFSDFDTMTDRLVTEILYHI----DSCA----LNPARISFVA 1308
            ....|..|  .:||||||.|:..|..||..|..||..|::..:    |..|    |...::|||.
plant   533 NQWLLIDP--KIEFLMSEANEEKTHGDFREMGQRLAQEVVSFLKRKKDRYARQGHLKSIKLSFVG 595

  Fly  1309 HSLGTIIVRSALARPQMRPLLPRLHTFLSLSGPHLGTLYNTSGLVNMGMWFMQKWKKSGSLLQLC 1373
            ||:|.:|:|:|:|...|.|....|||:|||||||||.||:|:.|.|.|:|.::|.|.:..:.||.
plant   596 HSIGNVIIRTAIADSLMEPYRKYLHTYLSLSGPHLGYLYSTNSLFNSGLWLLKKLKSTQVIHQLT 660

  Fly  1374 MRDTTDMRNSFLYRLSQRSTLHHFKNILLCGSSQDRYVPAHSARLELCKAAMRDSSSLGTIYREM 1438
            :.|..|:|::|.|:|.::.||.:||||:|..|.||.|||.||||:|.|:.|..|||..|..:.||
plant   661 LTDDPDLRHTFFYKLCKQKTLENFKNIILLSSPQDGYVPYHSARIESCQPASFDSSKRGVAFLEM 725

  Fly  1439 VHN----IIAPILARP--ELTLARFDVHHALP---HTANTLIGRAAHIAVLDSELFIEKFM 1490
            ::|    |..|:...|  :....|.||:..:.   ...|:.|||||||..|:|::|....|
plant   726 LNNCLDQIRGPVPEAPHQQRVFMRCDVNFDMTVYGRNLNSFIGRAAHIEFLESDIFARFIM 786

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32333	NP_001261246.1	DUF3657	150..226	CDD:289180
		MhpC	1223..>1447	CDD:223669	101/242 (42%)
		DUF676	1227..1422	CDD:282860	90/202 (45%)
ZW18	NP_001117514.1	DUF3657	147..208	CDD:372086
ZW18	NP_001117514.1	DUF676	508..710	CDD:309968	91/203 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	166	1.000	Domainoid score	I1201
eggNOG	1	0.900	-	-		E1_KOG2205
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	233	1.000	Inparanoid score	I1125
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001840
OrthoInspector	1	1.000	-	-		otm3458
orthoMCL	1	0.900	-	-		OOG6_102700
Panther	1	1.100	-	-	LDO	PTHR12482
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1527
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.820