DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tfc and REG4

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001152824.1	Gene:	REG4 / 83998	HGNCID:	22977	Length:	158	Species:	Homo sapiens

Alignment Length:	126	Identity:	31/126 - (24%)
Similarity:	56/126 - (44%)	Gaps:	13/126 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 GIFFK-ANWFKATQYCRYH--GMHLASISSQEENDRLEKHIRDFGLGHEHFWISGTDLADEGNFF 314
            |.|.| .||..|...|:.:  |.|||||.|.:|...:.::|..:... :..||...|......:.
Human    43 GYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRS-QPIWIGLHDPQKRQQWQ 106

  Fly   315 WMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETYFVCEVQP 375
            |: .|....:.:|:.       ...|..::|.|: :.:...|.|:.:.|:...:|:|:.:|
Human   107 WI-DGAMYLYRSWSG-------KSMGGNKHCAEM-SSNNNFLTWSSNECNKRQHFLCKYRP 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	30/122 (25%)
REG4	NP_001152824.1	CLECT_REG-1_like	30..156	CDD:153064	30/122 (25%)
		Carbohydrate-binding	98..103		1/4 (25%)
		Carbohydrate-binding	135..137		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BFQ9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1509611at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820