DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tfc and COLEC11

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001242914.1	Gene:	COLEC11 / 78989	HGNCID:	17213	Length:	285	Species:	Homo sapiens

Alignment Length:	154	Identity:	43/154 - (27%)
Similarity:	67/154 - (43%)	Gaps:	12/154 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 EVDNDCPNCVDESQYTPNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEEN 283
            |:||.......|.::..|  .:..::..|.:.||.:..:..:..|...|:..|..|:....:..|
Human   138 EMDNQVSQLTSELKFIKN--AVAGVRETESKIYLLVKEEKRYADAQLSCQGRGGTLSMPKDEAAN 200

  Fly   284 DRLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLEL 348
            ..:..::...||.  ..:|...||..||.|.:.......||..|.:||||| .|   :||:|:|:
Human   201 GLMAAYLAQAGLA--RVFIGINDLEKEGAFVYSDHSPMRTFNKWRSGEPNN-AY---DEEDCVEM 259

  Fly   349 WNRDGKGLKWNDSPCSFETYFVCE 372
            ....|    |||..|....||:||
Human   260 VASGG----WNDVACHTTMYFMCE 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	37/124 (30%)
COLEC11	NP_001242914.1	Collagen	58..111	CDD:189968
COLEC11	NP_001242914.1	CLECT_collectin_like	165..280	CDD:153061	37/125 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4956
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940