DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tfc and Clec4a3

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001191170.1	Gene:	Clec4a3 / 73149	MGIID:	1920399	Length:	237	Species:	Mus musculus

Alignment Length:	150	Identity:	39/150 - (26%)
Similarity:	59/150 - (39%)	Gaps:	34/150 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 PNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGH-- 297
            |..|.    ..|...|:......|:|.::.:.|.:.|.||..|.||||.|.: ..|.|.|..:
Mouse   108 PKDWK----PFGSYCYFTSTDLVASWNESKENCFHMGAHLVVIHSQEEQDFI-TGILDTGTAYFI 167

  Fly   298 --------EHFWISGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGK 354
                    :..||..|...|...|             |:.|||::      :.|.|:.:.:|...
Mouse   168 GLSNPGDQQWQWIDQTPYDDNTTF-------------WHKGEPSS------DNEQCVIINHRQST 213

  Fly   355 GLKWNDSPCSFETYFVCEVQ 374
            |..|:|.|||.:...:|.|:
Mouse   214 GWGWSDIPCSDKQNSICHVK 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	35/133 (26%)
Clec4a3	NP_001191170.1	DUF2418	41..>82	CDD:287321
Clec4a3	NP_001191170.1	CLECT_DC-SIGN_like	107..230	CDD:153060	37/145 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840883
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BFQ9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930