DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tfc and Asgr2

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_058885.1	Gene:	Asgr2 / 29403	RGDID:	2161	Length:	301	Species:	Rattus norvegicus

Alignment Length:	143	Identity:	45/143 - (31%)
Similarity:	69/143 - (48%)	Gaps:	24/143 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 PNKWTMPLLKLGEKRYYL---GIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLG 296
            |..|    ::.|...|:.   |:    .|.:|.|||:....||..|:|:||.:.:.||     .|
  Rat   171 PVNW----VEFGGSCYWFSRDGL----TWAEADQYCQMENAHLLVINSREEQEFVVKH-----RG 222

  Fly   297 HEHFWISGTDLADEGNFFWM-ATGRPITFTNWNAGEPNNFR-YENGEEENCLELWNRDGKGLKWN 359
            ..|.||..||  .:|::.|: .|.....|.||...:|:|:: :|.|..|:|.|:.: ||   .||
  Rat   223 AFHIWIGLTD--KDGSWKWVDGTEYRSNFKNWAFTQPDNWQGHEEGGSEDCAEILS-DG---LWN 281

  Fly   360 DSPCSFETYFVCE 372
            |:.|.....:.||
  Rat   282 DNFCQQVNRWACE 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	42/129 (33%)
Asgr2	NP_058885.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29
		Lectin_N	29..162	CDD:397859
		CLECT_DC-SIGN_like	170..295	CDD:153060	45/143 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344411
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930