DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tfc and Mbl1

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_036731.2	Gene:	Mbl1 / 24548	RGDID:	3055	Length:	238	Species:	Rattus norvegicus

Alignment Length:	134	Identity:	37/134 - (27%)
Similarity:	58/134 - (43%)	Gaps:	26/134 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 KLGEKRYYLGIFFKAN-----WFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWIS 303
            |.|:|      ||..|     :.|....|......:|...:.|||..:::      :.....::.
  Rat   123 KSGKK------FFVTNHERMPFSKVKALCSELRGTVAIPRNAEENKAIQE------VAKTSAFLG 175

  Fly   304 GTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETY 368
            .||...||.|.::..|| :|::||...|||    ::|..|:|:.:.:   .|| |||..|.....
  Rat   176 ITDEVTEGQFMYVTGGR-LTYSNWKKDEPN----DHGSGEDCVTIVD---NGL-WNDISCQASHT 231

  Fly   369 FVCE 372
            .|||
  Rat   232 AVCE 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	34/129 (26%)
Mbl1	NP_036731.2	Collagen	36..>88	CDD:189968
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..87
		CLECT_collectin_like	126..236	CDD:153061	35/131 (27%)
		Calcium-dependent carbohydrate binding. /evidence=ECO:0000269\|PubMed:11850428, ECO:0000269\|PubMed:1436090, ECO:0000269\|PubMed:9033386	202..210		4/11 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910