DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tfc and Sftpd

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_033186.1	Gene:	Sftpd / 20390	MGIID:	109515	Length:	374	Species:	Mus musculus

Alignment Length:	132	Identity:	44/132 - (33%)
Similarity:	67/132 - (50%)	Gaps:	21/132 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 LGEKRYYLGIFFKANWFK----ATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWISGT 305
            :|:|     ||..|:..|    |.:.|:..|..|||..|..||..:::.|.   ..::..::|.|
Mouse   259 VGDK-----IFRTADSEKPFEDAQEMCKQAGGQLASPRSATENAAIQQLIT---AHNKAAFLSMT 315

  Fly   306 DLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETYFV 370
            |:..||.|.: .||.|:.::||..|||||    ||..|||:|::...    :|||..|..:...:
Mouse   316 DVGTEGKFTY-PTGEPLVYSNWAPGEPNN----NGGAENCVEIFTNG----QWNDKACGEQRLVI 371

  Fly   371 CE 372
            ||
Mouse   372 CE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	42/128 (33%)
Sftpd	NP_033186.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..222
		Collagen	45..102	CDD:189968
		Collagen	129..>171	CDD:189968
		Surfac_D-trimer	223..267	CDD:286141	4/12 (33%)
		CLECT_collectin_like	261..374	CDD:153061	43/130 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43824
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910