DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tfc and Sftpa1

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_075623.2	Gene:	Sftpa1 / 20387	MGIID:	109518	Length:	248	Species:	Mus musculus

Alignment Length:	135	Identity:	34/135 - (25%)
Similarity:	63/135 - (46%)	Gaps:	22/135 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 LLKLGEKRYYLGIFF----KANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWI 302
            :|.:|:|     :|.    ..|:....:.|...|.|:|:..:.|||:.:....:.:   :.:.::
Mouse   131 MLSVGDK-----VFSTNGQSVNFDTIREMCTRAGGHIAAPRNPEENEAIASITKKY---NTYPYL 187

  Fly   303 SGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFET 367
            ...:....|:|.:: .|..:.:|||..|||..    .|:|: |:|::. ||   ||||..|....
Mouse   188 GVIEGQTPGDFHYL-DGASVNYTNWYPGEPRG----RGKEK-CVEMYT-DG---KWNDKGCLQYR 242

  Fly   368 YFVCE 372
            ..:||
Mouse   243 LAICE 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	31/128 (24%)
Sftpa1	NP_075623.2	Collagen	27..98	CDD:189968
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	28..100
		CLECT_collectin_like	136..248	CDD:153061	32/130 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910