DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tfc and clec-149

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_497267.2	Gene:	clec-149 / 186903	WormBaseID:	WBGene00019328	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	389	Identity:	89/389 - (22%)
Similarity:	145/389 - (37%)	Gaps:	112/389 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LIVVLISLASVDSGHNSPVTTIPVAEPISQ-VPHGFQLGQNNHISSSSNISR--SGGGNGRDKRG 67
            |:.||:::....:|     :::|...|.:: :..||.......|....:|..  ..|...:.:.|
Worm     7 LLPVLLNILYQPAG-----SSLPTFSPGNKHLCEGFGFNWAAEIRCLRDIINDCEEGTQEKSRGG 66

  Fly    68 AQLDPSEIARQNQITQQIFANYLERRLFP---NRTANQKIPTIADILPKPKPSPRPRPRGFAASD 129
            ..|..||....|  |.|  |:|.....:|   :||.::.  :|:.|.|   |.|.|.|:   .|.
Worm    67 RSLQRSEFPTDN--TPQ--ADYGNPYSYPRPYSRTYHRN--SISPIRP---PVPMPIPQ---ISQ 119

  Fly   130 GGNFKRSGGGAQRNRLAAAASKRQSGYNRKRLREEQEEEEEADDQERDQQPLANQEDFDYDVQE- 193
            |.|....        :.|..:|........::..:.|.|:...|.         ::.|:.|::|
Worm   120 GCNCNHD--------IEALEAKFDKKLYEVKMHAQYETEKGVGDL---------RKQFETDLREY 167

  Fly   194 ----SLQSVESEQHDQYYGNIFHRDPSENEVDNDCPNCVDESQYTPNKWTMPLLKLGEKRYYLGI 254
                :...||.::|..|.       .:....:||                            |..
Worm   168 ERITTKDIVEIKRHLDYL-------QAPRITNND----------------------------LEY 197

  Fly   255 FF---KANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLG--------HEHFWISGTDLA 308
            ||   :.:|:.|::.|..:|.|||||.|     |||       ||        ::..||...|:.
Worm   198 FFIQREESWYTASEKCIGYGAHLASIHS-----RLE-------LGFVQRLVPVNQTAWIGVNDIQ 250

  Fly   309 DEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETYFVCE 372
            .| |.|..:.|.|:.|..|...:|:|..:    .|||:|:   |..| :|.|..|.....|||:
Worm   251 KE-NVFRNSDGTPVDFYKWGKKQPDNQEH----NENCVEV---DHSG-QWTDKLCIITRPFVCK 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	42/135 (31%)
clec-149	NP_497267.2	CLECT	197..306	CDD:153057	41/130 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010