DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tfc and clec-151

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_497944.2	Gene:	clec-151 / 184310	WormBaseID:	WBGene00008659	Length:	591	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	68/417 - (16%)
Similarity:	130/417 - (31%)	Gaps:	160/417 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 ISSSSNISRSGGGNGRDKRGAQLDPSEIARQNQITQQIFANYLERRLFPNRTANQKIPTIADILP 112
            ::|.|...|:.....|::.    ||  :|..|..|:      |.:.:|....|...:|| .:.:.
Worm   235 VTSESAYMRTTSSRIRNEE----DP--LADHNYCTE------LMKPVFRGGEAQSALPT-QEFVK 286

  Fly   113 KPKPSPRPRPRGFAASDGGNFKRSGGGAQRNRLAAAASKRQSG-------------YNRKRLREE 164
            |...:                    |.|:..|.::.:.....|             |:|..::.:
Worm   287 KLTET--------------------GAAEIIRTSSVSMNANKGERTIVDCVSHVDPYHRVHVKGD 331

  Fly   165 QEEEEEADDQE---RDQQPLANQEDFD-----------YDVQESLQSVESEQHDQYYGNIFHRDP 215
            :.||......:   |.|:|   .|..|           .|....|:::...::...|
Worm   332 KNEETSITLNKTIWRQQEP---HETCDAATWSSAAVLSRDSNRGLEAMSDARYAPLY-------- 385

  Fly   216 SENEVDNDCPNCVDESQYT--PNKWT-MPLLKLGEK---RYYLGIFFKANWFKATQYCRYHGMHL 274
                    |.|.::...|:  |..:: .|.:..|::   :|..|.  ...:..|.:.|...|.||
Worm   386 --------CENILEYFSYSKCPEGFSEFPRVTSGQRWCHKYVHGA--PLPYDDAEKKCAEMGAHL 440

  Fly   275 ASISSQEE----NDRLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGR----PITFTNWNAGE 331
            :..::|||    |:.:.|.           :.:..|:.     .|:...|    |....|:|.|.
Worm   441 SGFTTQEEFKFLNELVNKE-----------YPNKNDIE-----VWLGAQRKMSCPDAGKNFNGGF 489

  Fly   332 PNN----------FRYENG--------------------------EEENCL--------ELWN-- 350
            ..|          |.:.||                          ::|.|:        :.|.
Worm   490 STNEFDNCARSRVFEWRNGVAKNPPDFIGSGYDNWAELDEPNHLSDKERCVVMMHGKITKYWGYS 554

  Fly   351 ---RDGKGLKWNDSPCSFETYFVCEVQ 374
               .|.:.::.||..|.:...:.|.::
Worm   555 SKYHDRRDMQINDIFCDWHFEYFCGLE 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	31/180 (17%)
clec-151	NP_497944.2	CLECT	98..>129	CDD:382969
clec-151	NP_497944.2	CLECT	398..578	CDD:214480	33/197 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1509611at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010