DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tfc and Asgr2

DIOPT Version :9

Sequence 1:	NP_612091.1	Gene:	tfc / 38141	FlyBaseID:	FBgn0035199	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001300854.1	Gene:	Asgr2 / 11890	MGIID:	88082	Length:	301	Species:	Mus musculus

Alignment Length:	147	Identity:	47/147 - (31%)
Similarity:	72/147 - (48%)	Gaps:	24/147 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 PNKWTMPLLKLGEKRYYL---GIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLG 296
            |..|    ::.|...|:.   |:    .|.:|.|||:....||..|:|:||.|.:.||...|
Mouse   171 PVNW----VEFGGSCYWFSRDGL----TWAEADQYCQLENAHLLVINSREEQDFVVKHRSQF--- 224

  Fly   297 HEHFWISGTDLADEGNFFWM-ATGRPITFTNWNAGEPNNFR-YENGEEENCLELWNRDGKGLKWN 359
              |.||..||  .:|::.|: .|.....:.||...:|:|:: :|.|..|:|.|:.: ||   .||
Mouse   225 --HIWIGLTD--RDGSWKWVDGTDYRSNYRNWAFTQPDNWQGHEQGGGEDCAEILS-DG---HWN 281

  Fly   360 DSPCSFETYFVCEVQPN 376
            |:.|.....:|||.:.|
Mouse   282 DNFCQQVNRWVCEKRRN 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tfc	NP_612091.1	CLECT	249..373	CDD:153057	42/128 (33%)
Asgr2	NP_001300854.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
		Lectin_N	29..162	CDD:281887
		CLECT_DC-SIGN_like	170..295	CDD:153060	45/142 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840990
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930