DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sac1 and SAC8

DIOPT Version :9

Sequence 1:	NP_001189016.1	Gene:	Sac1 / 38137	FlyBaseID:	FBgn0283500	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_190751.2	Gene:	SAC8 / 824346	AraportID:	AT3G51830	Length:	588	Species:	Arabidopsis thaliana

Alignment Length:	601	Identity:	220/601 - (36%)
Similarity:	326/601 - (54%)	Gaps:	54/601 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VYDDMNLYIAPQSFIIEP-NGGDELLVIGRHDKVTRVQP----ASGGLVANLRPTR--RICGVLG 66
            :||...|...|..::::| ...:|...:.|.|  ..::|    ||.|     .|||  .|.||.|
plant    12 LYDQFELLEFPDKYVVKPIESPEEGFSVNRRD--GNIKPLDENASSG-----SPTRVSTIYGVGG 69

  Fly    67 TIHLLSCDYLLVATHRLFVGVLNGAVVWRLAGYDIIPYIPN------SFQRKENENYLRLLRQTL 125
            ||.||:..||||.|.|..||...|..::|:.....:|.  |      :.|.|::|.|.|.|.|.|
plant    70 TIRLLAGTYLLVITSREEVGNFLGLPIFRVTAMKFLPC--NEALRFATAQEKKDETYFRTLLQAL 132

  Fly   126 D-TKFFYFSYRYDLTNSLQRQREVAQS---RPEVSGLLQRAEQRFVWNGYVLRQFNCDKMEKFQL 186
            : |...||||..|||.:|||:.::|:.   :|    :.::|:.|:|||.::|......|::.|.:
plant   133 ETTPGLYFSYETDLTLNLQRRCKLAEGWNRKP----MWKQADPRYVWNWHLLEDLIECKLDGFII 193

  Fly   187 PLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRGSDEQGHVANFVETEQIVEFNGQLTG 251
            |::.|...:.::::.......||::||..:|.|||::.||::.:|..|||||:|||||.||....
plant   194 PILQGSYQVAELKLKNSPAVVSIMSRRCTRRLGTRMWRRGANLEGDAANFVESEQIVEINGFKFS 258

  Fly   252 FVQTRGSMPFHWHQLPNLRYKPRPVLVPGKDHLAACGLHFKEQIRLYGNNVAVNLVDHKGAEGEL 316
            .:|.|||:|..|.|:.:|.||||..:...::.......||.:..:.||..:||:|.|..|.||.|
plant   259 LLQVRGSIPLLWEQIVDLSYKPRLKINKHEETPKVVQRHFHDLCQRYGEIMAVDLTDQHGDEGAL 323

  Fly   317 EATYARLVREMGNPQVRYESFDFHSECRKMRWDRLNILIDRLAHEQDQFGVYHVFDDGKLVSTQT 381
            ...||..:.::  |.|||.|||||..|....:|.|.:|.:::..|.::.|.:.|..|..::..|.
plant   324 SKAYATEMEKL--PDVRYVSFDFHQVCGTTNFDNLGVLYEQIGDEFEKQGYFLVDADENILEEQK 386

  Fly   382 GVFRTNCIDCLDRTNVVQSMLARRSLTAVLQKLGVLHVGQKVEHASDIFESIFKGVWADNADLVS 446
            ||.|:|||||||||||.||.:.::||...||::||....:.:....|.:.. |:.:||:..|.||
plant   387 GVIRSNCIDCLDRTNVTQSFMGQKSLNLQLQRIGVCDSTECISTFEDDYTK-FRTIWAEQGDEVS 450

  Fly   447 LQYSGTCALKTDFTRTGKRTKSGAMQDGKNSLMRYYLNNFADGQRQDSIDLFLGKYLVNDNEGGA 511
            |||:||.|||.|..|.||:|.:||::||.:::.|||||||.||.|||::||..|:|.|    |..
plant   451 LQYAGTYALKGDLVRYGKQTMTGAIKDGLSAMSRYYLNNFQDGVRQDALDLISGRYTV----GTH 511

  Fly   512 VPS---PLESKHGWRFFTFPSVLLVAVAMFM--ITMT----YPAEFNTENLLFMLFWGAMIAVSA 567
            .||   |:.|:        ||.|.||.|:.:  :|:|    :.|..||:..|....|..:.|...
plant   512 SPSQLQPIGSQ--------PSFLPVASALLIGGVTVTSFTIHQAGRNTQQYLASALWAGVTAGVV 568

  Fly   568 TGILHYGVEFVQWPRL 583
            ..|...|......|||
plant   569 AMIKANGRHLTSRPRL 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sac1	NP_001189016.1	COG5329	3..566	CDD:227637	215/582 (37%)
Sac1	NP_001189016.1	Syja_N	62..344	CDD:280532	108/291 (37%)
SAC8	NP_190751.2	Syja_N	65..348	CDD:280532	108/290 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	181	1.000	Domainoid score	I1030
eggNOG	1	0.900	-	-		E1_COG5329
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	345	1.000	Inparanoid score	I629
OMA	1	1.010	-	-		QHG55111
OrthoDB	1	1.010	-	-		D359616at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2500
orthoMCL	1	0.900	-	-		OOG6_101364
Panther	1	1.100	-	-	O	PTHR45662
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1717
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840