DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sac1 and AT3G14205

DIOPT Version :9

Sequence 1:	NP_001189016.1	Gene:	Sac1 / 38137	FlyBaseID:	FBgn0283500	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_566481.1	Gene:	AT3G14205 / 820638	AraportID:	AT3G14205	Length:	808	Species:	Arabidopsis thaliana

Alignment Length:	597	Identity:	173/597 - (28%)
Similarity:	262/597 - (43%)	Gaps:	136/597 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDSRE--ENAVYDDMNLYIAPQSFIIEPNGGDELLVIGRHDKVTRVQP---ASGGLVANLRPTRR 60
            :|..|  |..:|:|...|...:.|                :.:.|:..   :|||    |:....
plant    48 LDRTEPAEVNIYEDSTAYTEAECF----------------ETLRRIHEGNRSSGG----LKFVTT 92

  Fly    61 ICGVLGTIHLLSCDYLLVATHRLFVGVLNGAVVWRLAGYDI--IPY---IPNSFQRKENENYLRL 120
            ..|::|.|..|...|:|:.|.|..:|.:.|..|:.:|...|  ||:   :.|....|:.:.|.||
plant    93 CYGIIGFIRFLGPYYMLIITKRKKLGEICGHTVYGVAKSKIITIPHASVLSNVAYSKDEKRYKRL 157

  Fly   121 LRQTLD-TKFFYFSYRYDLTNSLQRQREVAQSRPEVSGLLQRAEQRFVWNGYVLRQF-NCDKMEK 183
            | .|:| ||.|:|||.|.:.::|||...     ..|.|... .|..||||.|:.|:. |..|...
plant   158 L-CTVDLTKDFFFSYSYHIMHTLQRNLS-----NNVEGHTY-YESMFVWNEYLTRRIRNNVKDCM 215

  Fly   184 FQLPLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRGSDEQGHVANFVETEQIV----- 243
            :.:.||.||....::.::.:.|..::|:|||...||||...||.:|:|.|||.|||||||
plant   216 WTVALVYGFFKQVKLSVSEKNFRLTLISRRSRHYAGTRYLKRGVNEKGRVANDVETEQIVFEEAQ 280

  Fly   244 EFN-GQLTGFVQTRGSMPFHWHQ-LPNLRYKPRPVLVPGKDHLAACGLHFKEQIRLYGNNVAV-N 305
            :.| |:::..||.|||:|..|.| ...|..||..:|.|...:..|..|||:...|.|||.:.: |
plant   281 DGNPGRISSVVQNRGSIPLFWSQETSRLNIKPDIILSPKDPNFEATRLHFENLGRRYGNPIIILN 345

  Fly   306 LV---DHKGAEGELEATYARLVREMG-----NPQVRYESFDFHSECRKMRWDRLNILIDRLA--- 359
            |:   :.:..|..|.|.:|..:|.:.     ..::|...:|.|...||...:.|.|| .|||
plant   346 LIKTREKRPRETILRAEFANAIRFINKGLSKEDRLRPLHWDLHKHSRKKGTNVLAIL-GRLATYA 409

  Fly   360 -----------------------------HEQDQFGVYH-----------VFDDG---------- 374
                                         ::..:...|.           |.::|
plant   410 LNLTSIFYCQLTPDLRGEGFQNQNPSTLENDDGECSTYDPPSKDETAPNLVVENGNDSKDAKEDQ 474

  Fly   375 --KLVSTQTGVFRTNCIDCLDRTNVVQSMLARRSLTAVLQKLGVLHVGQKVEHASDIFESI---- 433
              ::...|.||.|||||||||||||.|            ...|::..|::: ||..:.||.
plant   475 QKEVTMLQKGVLRTNCIDCLDRTNVAQ------------YAYGLVAFGRQL-HALGLTESTNIDL 526

  Fly   434 -------FKGVWADNADLVSLQYSGTCALKTDF-TRTGKRTKSGAMQDGKNSLMRYYLNNFADGQ 490
                   ..|::....|.::|||.|:.|....| .|.|:...:...|:...:|.|||.|.:.|.:
plant   527 DNPLAEDLMGIYETMGDTLALQYGGSAAHNKIFCERRGQWRAATQSQEFFRTLQRYYSNAYMDAE 591

  Fly   491 RQDSIDLFLGKY 502
            :||:|::|||.:
plant   592 KQDAINVFLGYF 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sac1	NP_001189016.1	COG5329	3..566	CDD:227637	172/595 (29%)
Sac1	NP_001189016.1	Syja_N	62..344	CDD:280532	104/304 (34%)
AT3G14205	NP_566481.1	Syja_N	94..392	CDD:396798	104/304 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5329
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D359616at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820