DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sac1 and CG7956

DIOPT Version :9

Sequence 1:	NP_001189016.1	Gene:	Sac1 / 38137	FlyBaseID:	FBgn0283500	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001036740.2	Gene:	CG7956 / 42545	FlyBaseID:	FBgn0038890	Length:	1142	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	172/460 - (37%)
Similarity:	254/460 - (55%)	Gaps:	37/460 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 PNSFQRKENENYLRLLRQTLDTKFFYFSYRYDLTNSLQR---QREVAQSRPEVSGLLQRAEQRFV 167
            |...:|:..|...::..:| |:  ||||:..|:||:|||   :.|.:||:|         ::||.
  Fly   184 PRHIERRITEELHKIFDET-DS--FYFSFDCDITNNLQRHEAKSEESQSQP---------DERFF 236

  Fly   168 WNGYVLRQFNCDKMEKFQLPLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRGSDEQGH 232
            ||.:::|.......:.:.||::.||:.:....|..:.|..::::|||..|||||...||.||:|:
  Fly   237 WNKHMIRDLINLNDKTWILPIIQGFMQVENCVIGNECFTLALVSRRSRHRAGTRYKRRGVDEKGN 301

  Fly   233 VANFVETEQIVEFNGQLTGFVQTRGSMPFHWHQLPNLRYKPRPVLVPG-KDHLAACGLHFKEQIR 296
            .||:||||||:.|......|.|.|||:|.:|.| |..:|:|.|.|..| .:...|..|||.:::.
  Fly   302 CANYVETEQILSFRHHQLSFTQVRGSVPIYWSQ-PGYKYRPPPRLDRGVAETQQAFELHFTKELE 365

  Fly   297 LYGNNVAVNLVDHKGAEGELEATYARLVREMGNPQVRYESFDFHSECRKMRWDRLNILIDRLAHE 361
            .||....||||:..|.|..:...||..|.::.|.::.|.:||||..||.||::.::.|||.:..|
  Fly   366 TYGRVCIVNLVEQSGKEKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPE 430

  Fly   362 QDQFGVYHVFDDGKLVSTQTGVFRTNCIDCLDRTNVVQSMLARRSLTAVLQKLGVLHVGQKVEHA 426
            ....| :|..|...::..|..|||.||:||||||||||:.:.:..|.:.|.|||   :.......
  Fly   431 AGAMG-FHWRDQRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLVKLG---LSPPYTPI 491

  Fly   427 SDIFESIFKGVWADNADLVSLQYSGTCALKTDFTRTGKRTKSGAMQDGKNSLMRYYLNNFADGQR 491
            .:..:|.|..:||:|.|::|.||:||.|||.|:||||:|..||.|:||.||..|:::.||||..|
  Fly   492 PEQLKSPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMNSANRFFIQNFADSFR 556

  Fly   492 QDSIDLFLGKYL-VNDNEGGAVPSPL------ESK---HGWRFFTFPSVL---LVAVAMFMITMT 543
            |..|||..|:.| ..|.:...|.|.:      |::   ||   :..|.||   |..:...:.|..
  Fly   557 QCIIDLMQGQLLRAEDLQEDEVLSTILQILTPETRPPLHG---YYNPGVLGPELQLLESIVTTSY 618

  Fly   544 YPAEF 548
            |.|.|
  Fly   619 YLARF 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sac1	NP_001189016.1	COG5329	3..566	CDD:227637	172/460 (37%)
Sac1	NP_001189016.1	Syja_N	62..344	CDD:280532	87/241 (36%)
CG7956	NP_001036740.2	Syja_N	174..413	CDD:280532	87/241 (36%)
		COG5329	<197..586	CDD:227637	158/405 (39%)
		hSac2	663..768	CDD:289241
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447419
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153624at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950