Protein Alignment Sac1 and Synj2

DIOPT Version :10

• Sequence 1: NP_612087.1
• Gene: Sac1 / 38137
• FlyBaseID: FBgn0283500
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_001106824.1
• Gene: Synj2 / 20975
• MGIID: 1201671
• Length: 1479
• Species: Mus musculus
• Alignment Length: 564
• Identity: 164/564 - (29%)
• Similarity: 249/564 - (44%)
• Gaps: 129/564 - (22%)

  Fly    19 PQSFIIEPNG-GDELLVIGRHDKVTRVQPASGGLVANLRPTRR------------ICGVLGTIHL 70
            |.|.::|..| ||.||.             ..|.||.|.|..:            ..|.||.:.|
Mouse    18 PSSVLLEARGRGDCLLF-------------EAGAVATLAPEEKEVIKGLYSKLTDAYGCLGELRL 69

  Fly    71 LS----CDYLLVATHRLFVGVLNGAVVWRLAGYDIIPYIPNSFQRKENENYLRLLRQTLDTKFFY 131
            .|    ..:|::.|..:.||.:..|.::::...::.|.    .:..:.|:.|..|::.|.:..||
Mouse    70 QSGGVPLSFLVLVTGCMSVGRIPDAEIYKITATELYPL----QEEAKEEDRLPTLKKILSSGVFY 130

  Fly   132 FSYR-----YDLTNSLQRQREVAQSRPEVSGLLQRAE--QRFVWNGYV---LR--QFNCDKMEKF 184
            |::.     :|||...|:|.:            ..:|  ..|.||..:   ||  |.||   ..:
Mouse   131 FAWPNDGACFDLTIRAQKQGD------------DGSEWGTSFFWNQLLHVPLRQHQVNC---HNW 180

  Fly   185 QLPLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRGSDEQGHVANFVETEQIVEFNGQL 249
            .|.::.|.|:|..|..:.:.....:|:|.|.:|||.|...||.::.|||:|||||||.:..:..:
Mouse   181 LLKVICGVVTIRTVYASHKQAKACLISRISCERAGARFLTRGVNDDGHVSNFVETEQTIYMDDGV 245

  Fly   250 TGFVQTRGSMPFHWHQLPNLRYKPRPVLVPGKDHLAACGLH----------------FKEQIRLY 298
            :.|||.|||:|..|.|         |.|..|..||.   ||                .|||   |
Mouse   246 SSFVQIRGSVPLFWEQ---------PGLQVGSHHLR---LHRGLEANAPAFERHMVLLKEQ---Y 295

  Fly   299 GNNVAVNLVDHKGAEGELEATYARLV----REMGNPQVRYESFDFHSECRKMRWDRL-NILIDRL 358
            |..|.|||:..:|.|..|...:.:|:    .....|.:   :||||...:..:.::| |:|..:|
Mouse   296 GKQVVVNLLGSRGGEEVLNRAFKKLLWASCHAGDTPMI---NFDFHQFAKGRKLEKLENLLRPQL 357

  Fly   359 AHEQDQFGVYHVFDDGKLVST--QTGVFRTNCIDCLDRTNVVQSMLARRSLTAVLQKLGVLHVGQ 421
            ....:.||   ||..|:.||.  |.|..|.||:|||||||.||..:|...|...|:.||:
Mouse   358 QLHWEDFG---VFAKGENVSPRFQKGTLRMNCLDCLDRTNTVQCFIALEVLHLQLESLGL----- 414

  Fly   422 KVEHASDIFESIFKGVWADNADLVSLQYSGTCALKTDFTRTGKRTKSGAMQDGKNSLMRYYLNNF 486
            ..:...|.|...||.:|:.|...:|..::|:.||:      || .|.|.::||..|:.|...:||
Mouse   415 NSKPIIDRFVESFKAMWSLNGHSLSKVFTGSRALE------GK-AKVGKLKDGARSMSRTIQSNF 472

  Fly   487 ADGQRQDSIDLFL------------GKYLVNDNEGGAVPSPLES 518
            .||.:|::|.|.|            |:.|:::....|.|..|::
Mouse   473 FDGVKQEAIKLLLVGDVYNEESTDKGRMLLDNTALLATPRILKA 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sac1	NP_612087.1	COG5329	3..566	CDD:227637	164/564 (29%)
Synj2	NP_001106824.1	COG5329	30..485	CDD:227637	153/519 (29%)
		EEP	530..861	CDD:469791
		DUF1866	872..1008	CDD:286093
		Atrophin-1	1120..>1455	CDD:460830