Protein Alignment Sac1 and Synj1

DIOPT Version :10

• Sequence 1: NP_612087.1
• Gene: Sac1 / 38137
• FlyBaseID: FBgn0283500
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: XP_011244377.1
• Gene: Synj1 / 104015
• MGIID: 1354961
• Length: 1714
• Species: Mus musculus
• Alignment Length: 550
• Identity: 157/550 - (28%)
• Similarity: 253/550 - (46%)
• Gaps: 93/550 - (16%)

  Fly     3 SREENAVYDDMNLYIA------------PQSFIIEPNGGDELLVIGRHDKVTRVQPASGGLVANL 55
            ||.:.|..::..:..:            |.|.|:|....:|.|:.            ..|.||.|
Mouse   133 SRRKRAASEERRMAFSKGFRIYHKLDPPPFSLIVETRHKEECLMF------------ESGAVAVL 185

  Fly    56 RPTRR------------ICGVLGTIHLLSCD----YLLVATHRLFVGVLNGAVVWRLAGYDIIPY 104
            ....:            ..|:||.:.|...|    ||::.|..:.||.:..:.|:|:...:.|..
Mouse   186 SSAEKEAIKGTYAKVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISL 250

  Fly   105 IPNSFQRKENENYLRLLRQTLDTKFFYFSYR---YDLTNSLQRQREVAQSRPEVSGLLQRAEQRF 166
            ..::    .:|:.:..:|:.|::..|||::.   ..|..||...|.:.:         ...:.||
Mouse   251 RVDA----SDEDRISEVRKVLNSGNFYFAWSASGVSLDLSLNAHRSMQE---------HTTDNRF 302

  Fly   167 VWNGYV---LRQF--NCDKMEKFQLPLVLGFVSINQVQINGQTFFWSIITRRSVQRAGTRLFCRG 226
            .||..:   |:.:  |||   .:.|.|:.|.|.|..:....:.....:|:|.|.:|||||...||
Mouse   303 FWNQSLHLHLKHYGVNCD---DWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRG 364

  Fly   227 SDEQGHVANFVETEQIVEFNGQLTGFVQTRGSMPFHWHQLPNLRYKPRPVLV--------PGKDH 283
            :::.|||||||||||::..:..::.|:|.|||:|..|.| |.|:.....|.:        |..|.
Mouse   365 TNDDGHVANFVETEQVIYLDDCVSSFIQIRGSVPLFWEQ-PGLQVGSHRVRMSRGFEANAPAFDR 428

  Fly   284 LAACGLHFKEQIRLYGNNVAVNLVDHKGAEGEL-EATYARLVREMGNPQVRYESFDFHSECRKMR 347
                  ||:....|||..:.|||:..|..|..| :|..:.|........:...|||:|...:..:
Mouse   429 ------HFRTLKDLYGKQIVVNLLGSKEGEHMLSKAFQSHLKASEHASDIHMVSFDYHQMVKGGK 487

  Fly   348 WDRLNILIDRLAHEQDQFGVYHVFDDGKLVSTQTGVFRTNCIDCLDRTNVVQSMLARRSLTAVLQ 412
            .::|:.::.....:...:|.:: ||..::...|:|..||||:|||||||.||:.|....|...|:
Mouse   488 AEKLHSILKPQVQKFLDYGFFY-FDGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLE 551

  Fly   413 KLGVLHVGQKVEHASDIFESIFKGVWADNADLVSLQYSGTCALKTDFTRTGKRTKSGAMQDGKNS 477
            .||:....|.|..    |:.:|:.:|:.|.|.:|..|:||.||:      || .|:|.::||..|
Mouse   552 ALGLAEKPQLVTR----FQEVFRSMWSVNGDSISKIYAGTGALE------GK-AKAGKLKDGARS 605

  Fly   478 LMRYYLNNFADGQRQDSID-LFLGKYLVND 506
            :.|...|||.|..:|::|| |.||..|.:|
Mouse   606 VTRTIQNNFFDSSKQEAIDVLLLGNTLNSD 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sac1	NP_612087.1	COG5329	3..566	CDD:227637	156/549 (28%)
Synj1	XP_011244377.1	COG5329	204..627	CDD:227637	139/457 (30%)
		INPP5c_Synj1	680..1015	CDD:197332
		RRM_SF	1014..1155	CDD:473069
		PHA03247	<1207..1609	CDD:223021