DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Psf1 and kif14

DIOPT Version :9

Sequence 1:	NP_612086.1	Gene:	Psf1 / 38136	FlyBaseID:	FBgn0035194	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	XP_005170522.1	Gene:	kif14 / 562052	ZFINID:	ZDB-GENE-030131-5759	Length:	1506	Species:	Danio rerio

Alignment Length:	189	Identity:	35/189 - (18%)
Similarity:	64/189 - (33%)	Gaps:	51/189 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KAFDLLKELERSSQTIPAFDDDGVRQ---VLEEIKAIFE-------ENVAQASSYNASGDRSLWP 65
            :.|...:::|::.|.|...:.|.:.|   ..:..|..|:       |..|..||.....::...|
Zfish   243 RPFSSREKIEKACQVIFMENQDTLVQHPDTKQTHKFTFDFSFCSINEADASFSSQQLIYEKLARP 307

  Fly    66 LLNFRHAALQRNKRCLLAY--------------------LYERCRRIKALRWEFGPIIPGDIKQA 110
            ||   ..|.:....||.||                    :...|..:      |..:...:.|:.
Zfish   308 LL---ERAFEGFNTCLFAYGQTGSGKSYTMMGFGEETGVIPRFCEEL------FSRLARSETKEM 363

  Fly   111 LCEPEVTFFNNYSKSLAAYMCSAGYNQGLPIDLTNNLRPPKSLYIEVRCMEDYGKFELD 169
            .|..|:::|..|::.:...:.:.        |..|..:.|    :.||....||.:..|
Zfish   364 SCHLEMSYFEVYNEKIHDLLVAK--------DEQNQKKMP----LRVREHPVYGPYVAD 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Psf1	NP_612086.1	GINS_A_psf1	9..134	CDD:212548	27/152 (18%)
Psf1	NP_612086.1	GINS_B	153..201	CDD:425409	5/17 (29%)
kif14	XP_005170522.1	KISc	235..586	CDD:214526	35/189 (19%)
		KISc_KIF1A_KIF1B	236..586	CDD:276816	35/189 (19%)
		Kinesin_assoc	583..701	CDD:292801
		FHA	681..778	CDD:238017
		Prefoldin	806..878	CDD:298833
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910