DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Psf1 and KIF27

DIOPT Version :9

Sequence 1:	NP_612086.1	Gene:	Psf1 / 38136	FlyBaseID:	FBgn0035194	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	XP_011517150.1	Gene:	KIF27 / 55582	HGNCID:	18632	Length:	1427	Species:	Homo sapiens

Alignment Length:	145	Identity:	27/145 - (18%)
Similarity:	54/145 - (37%)	Gaps:	25/145 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 GDRSLWPLLNFRHAALQRNKRCLLAYLYERCRRIKALRWEFGPIIPGDIKQALCEPEVTFFNNYS 123
            |..:|...:.:|:.::|..::.|.|..:...|....:..:...:.|.:|:..|    ..:||...
Human  1087 GIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACLSPVEIRTIL----FRYFNKVV 1147

  Fly   124 KSLAAYMCSAGYNQGLP---IDLTNNLRPPKSLYIEVRCMEDYGKFELDDGEVIHLKKNSQHYLP 185
            ....|......||:.:.   ::..|.:|       |:....|:.|.:.|....:..|::.|.
Human  1148 NLREAERKQQLYNEEMKMKVLERDNMVR-------ELESALDHLKLQCDRRLTLQQKEHEQK--- 1202

  Fly   186 RAQVESLVRQGILHH 200
                    .|.:|||
Human  1203 --------MQLLLHH 1209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Psf1	NP_612086.1	GINS_A_psf1	9..134	CDD:212548	13/74 (18%)
Psf1	NP_612086.1	GINS_B	153..201	CDD:425409	10/48 (21%)
KIF27	XP_011517150.1	KISc_KIF4	4..342	CDD:276823
		KISc	5..348	CDD:214526
		COG1340	820..1077	CDD:224259
		DUF4200	826..>910	CDD:290574
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910