DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Psf1 and kif3a

DIOPT Version :9

Sequence 1:	NP_612086.1	Gene:	Psf1 / 38136	FlyBaseID:	FBgn0035194	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	NP_001017604.2	Gene:	kif3a / 550267	ZFINID:	ZDB-GENE-050417-71	Length:	701	Species:	Danio rerio

Alignment Length:	196	Identity:	45/196 - (22%)
Similarity:	72/196 - (36%)	Gaps:	46/196 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EKAFDLLKELERSSQTIPAFDDDGVRQVLEEIKAIFEENVAQASSYNASGDRSLWPLL---NFRH 71
            ::|..|.:|||...|.         |..:||.....:|. ||..:...   :.:|.:|   ....
Zfish   510 KRAEQLRRELEEKEQE---------RLDIEEKYTSLQEE-AQGKTKKL---KKVWTMLMAAKSEM 561

  Fly    72 AALQRNKRCLLAYLYERCRRI-KALRWEFGPIIPGDIKQALCEPEVTFFNNY---SKSLAAYMCS 132
            |.||:.....:..|.|..|:: :.||.:. .||...|.|...|    ...||   ::.:..:...
Zfish   562 ADLQQEHHREIEGLLENIRQLSRELRLQM-LIIDNFIPQEYQE----MIENYVHWNEDIGEWQLK 621

  Fly   133 AGYNQGLPIDLTNNLRPPKSLYIEVRCMEDYGKFELDDGEVIHLKKNSQHYLPRAQVESLVRQGI 197
            .....|      ||:|  |...:..:..:|  .||:|...|         ||  |..|..:||.:
Zfish   622 CVAYTG------NNMR--KQTPVSDKKEKD--PFEVDLSHV---------YL--AYTEESMRQSL 665

  Fly   198 L 198
            :
Zfish   666 M 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Psf1	NP_612086.1	GINS_A_psf1	9..134	CDD:212548	29/130 (22%)
Psf1	NP_612086.1	GINS_B	153..201	CDD:425409	11/46 (24%)
kif3a	NP_001017604.2	KISc_KIF3	16..348	CDD:276822
kif3a	NP_001017604.2	Kinesin	23..348	CDD:278646
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910