Protein Alignment Klp61F and HIK

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_173273.2
• Gene: HIK / 838418
• AraportID: AT1G18370
• Length: 974
• Species: Arabidopsis thaliana
• Alignment Length: 1030
• Identity: 254/1030 - (24%)
• Similarity: 448/1030 - (43%)
• Gaps: 241/1030 - (23%)

  Fly     3 ISGGNTSRQPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSKL--TKKFT 65
            ::.|.:||..::|    |.|.||:||:|.||...:.....:.|....:|::..:..:|  ...||
plant    19 VTPGGSSRSREEK----IVVTVRLRPMNKRELLAKDQVAWECVNDHTIVSKPQVQERLHHQSSFT 79

  Fly    66 FDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSD 130
            ||:.|||||...:||...|..:....|.|.|.|:||||||.:|||:||
plant    80 FDKVFGPESLTENVYEDGVKNVALSALMGINATIFAYGQTSSGKTYTM----------------- 127

  Fly   131 IGIIPRALSHLFDE-LRMMEVEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVIIQG 194
            .|:..:|::.:::. ::..|.::|::||.||:|||.:.|||::|....:::.|| .:||:|:.:.
plant   128 RGVTEKAVNDIYNHIIKTPERDFTIKISGLEIYNENVRDLLNSDSGRALKLLDD-PEKGTVVEKL 191

  Fly   195 LEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHI--RENGIEGEDMLK--IG 255
            :|| ..::.:.:..|:...:.:|:...|.:|..|||||.:..:.:..  |||    .|.::  :.
plant   192 VEE-TANNDNHLRHLISICEAQRQVGETALNDTSSRSHQIIRLTIQSTHREN----SDCVRSYMA 251

  Fly   256 KLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALV--DRAPHVPYRESKLTRLLQ 318
            .||.|||||||..|:: ...|.|:||..:||.||:||..||..|.  .|:.|:|||:|||||:||
plant   252 SLNFVDLAGSERASQS-QADGTRLREGCHINLSLMTLTTVIRKLSVGKRSGHIPYRDSKLTRILQ 315

  Fly   319 ESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEIDKLK 383
            .||||..:|:||.|:||....:|::.:||.:|:|||.:.|...||..::.|.::|...:|:.:|:
plant   316 HSLGGNARTAIICTLSPALAHVEQSRNTLYFANRAKEVTNNAHVNMVVSDKQLVKHLQKEVARLE 380

  Fly   384 RDLMAARDKNGIYLAEETYGEIT---LKLESQNRELNEKMLLLKALKDELQNKEKIFSEVSMSLV 445
            .:             ..|.|..|   .|::....|:.|    |:..:|:.|          :.|.
plant   381 AE-------------RRTPGPSTEKDFKIQQMEMEIGE----LRRQRDDAQ----------IQLE 418

  Fly   446 EKTQELKKTEENLLNTKG-----------------TLLLTKKVLTKTKRRYKEKKELVASHMKTE 493
            |..|:|:..::   ..||                 ::.:|.....||..|.:..::
plant   419 ELRQKLQGDQQ---QNKGLNPFESPDPPVRKCLSYSVAVTPSSENKTLNRNERARK--------- 471

  Fly   494 QVLTTQAQEILAAADLATDD-THQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQ 557
               ||..|.::..:..|... .|::       |:|:.
plant   472 ---TTMRQSMIRQSSTAPFTLMHEI-------RKLEH---------------------------- 498

  Fly   558 DQQAALKEQLSQEMVNSSYVSQRLALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVMKISDQHS 622
                 |:|||.:|              ::|::|:        ||.:...|        ::.:|.:
plant   499 -----LQEQLGEE--------------ATKALEV--------LQKEVACH--------RLGNQDA 528

  Fly   623 QAFVAKLMEQMQQQQLL----MSKEIQTNLQVIEENNQRHKAMLDSMQEKFATIID--SSLQSVE 681
            ...:|||..::::.:.:    |.||:.   .||..|    |::..:::|:...:..  |::.::|
plant   529 AQTIAKLQAEIREMRTVKPSAMLKEVG---DVIAPN----KSVSANLKEEITRLHSQGSTIANLE 586

  Fly   682 EHAKQMHKKLEQLGAMSLPDAEELQNLQEELANERALAQQEDALLESMMMQMEQIKNL-RSKNSI 745
            |..:.:.|.:::| .||||     .|:.         |..|....::...|.::.|.| .:.:|.
plant   587 EQLESVQKSIDKL-VMSLP-----SNIS---------AGDETPKTKNHHHQSKKKKLLPLTPSSA 636

  Fly   746 SMSVHLNKMEESRLTRNHRIDDIKSGIQDYQKLGIEASQSAQAELTSQM-------EAGMLCLDQ 803
            |...:..|...|.|:.:.::.|..:..:..|:....|::.|.....|:.       |:|.:...:
plant   637 SNRQNFLKSPCSPLSASRQVLDCDAENKAPQENNSSAARGATTPQGSEKETPQKGEESGDVSSRE 701

  Fly   804 GVANC-SMLQVHMKNLNQKYEKETNENVGSVRVHHNQVE---IICQESKQQLEAVQEKTEVN--L 862
            |.... ....|:||.:.|.::....|||.|:|.:..:::   ...|..||.|.....:.|.|  .
plant   702 GTPGYRRSSSVNMKKMQQMFQNAAEENVRSIRAYVTELKERVAKLQYQKQLLVCQVLELEANDGA 766

  Fly   863 EQMVDARQQLITEDRQ--RFIGHATVATDLVQESNRQFSE--HAEH----------------QRQ 907
            ...|:..:..|.||.:  :...|.|..     |..:|..|  |..|                |..
plant   767 GYSVENEENTIMEDEEQNQVAWHITFI-----EERQQIIELWHVCHVSIIHRTQFYLLFKGDQAD 826

  Fly   908 QLQICEQELVRFQQSELKTYAPTGTTPSKRDFVYPRTLVATSPHQEIVRRYRQEL 962
            |:.: |.||.|....|.........||::.   ...::|:.|...:.:||.|:.|
plant   827 QIYM-EVELRRLTWLEQHLAEVGNATPARN---CDESVVSLSSSIKALRREREFL 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	129/356 (36%)
		SMC_prok_B	<408..728	CDD:274008	57/343 (17%)
		SMC_prok_B	<651..>921	CDD:274008	64/305 (21%)
		Microtub_bind	923..>1004	CDD:464048	9/40 (23%)
HIK	NP_173273.2	KISc_CENP_E	31..353	CDD:276825	127/349 (36%)
		COG4913	<467..>599	CDD:443941	33/220 (15%)
		DUF3490	791..955	CDD:463424	21/96 (22%)