Protein Alignment Klp61F and ARK3

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001184972.1
• Gene: ARK3 / 837799
• AraportID: AT1G12430
• Length: 920
• Species: Arabidopsis thaliana
• Alignment Length: 1005
• Identity: 262/1005 - (26%)
• Similarity: 439/1005 - (43%)
• Gaps: 223/1005 - (22%)

  Fly     5 GGNTSRQPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTL--DSKLTKKFTFD 67
            ||..:..|.:     ::|.||:||.|. |..|..|:..|.|..:..:.|..|  ::..|..|.||
plant    61 GGGDAGVPGR-----VRVAVRLRPRNG-EELIADADFADCVELQPELKRLKLRKNNWDTDTFEFD 119

  Fly    68 RSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIG 132
            ......:.|..||.||..|::|.||:|||.|:.||||||||||:|:  .:..|     ||.:|.|
plant   120 EVLTEYASQKRVYEVVAKPVVEGVLDGYNGTIMAYGQTGTGKTYTL--GQLGE-----EDVADRG 177

  Fly   133 IIPRALSHLFDELRMMEVEYTMRISYLELYNEELCDLL--STDDTTKIRIFDDSTKKGSVIIQGL 195
            |:.||:..:..|: .:|.: ::.:|||:||.|.:.|||  |.|:   |.|.:| .|.|.|.:.|.
plant   178 IMVRAMEDILAEV-SLETD-SISVSYLQLYMETVQDLLDPSNDN---IAIVED-PKNGDVSLPGA 236

  Fly   196 EEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIR-----ENGIEGED----- 250
            ..:.:..:....:||:.|:..|..|.|.:|.:|||||.:  ::|::|     .:|:..|.
plant   237 TLVEIRDQQSFLELLQLGEAHRFAANTKLNTESSRSHAI--LMVNVRRSMKTRDGLSSESNGNSH 299

  Fly   251 --------MLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDRAPHVP 307
                    :::.|||.:|||||||.::|:|:| |..:.|..:||.||..||:.|.||.:.:.|||
plant   300 MTKSLKPPVVRKGKLVVVDLAGSERINKSGSE-GHTLEEAKSINLSLSALGKCINALAENSSHVP 363

  Fly   308 YRESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVL 372
            :|:|||||||::|.||..:||::.||.|..:...||.||:.:..||..::|..::.
plant   364 FRDSKLTRLLRDSFGGTARTSLVITIGPSPRHRGETTSTIMFGQRAMKVENMVKIK--------- 419

  Fly   373 KEYTEEIDKLKRDLMAARDKNGIYLAEETYGEITLKLESQNRELNEKMLLLKALKDELQNKEKIF 437
                ||.|                     |..::.:||.|          |..|.:|.:.::|.|
plant   420 ----EEFD---------------------YKSLSRRLEVQ----------LDNLIEENERQQKAF 449

  Fly   438 -SEVSMSLVEKTQELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKKELVASHMKTEQVLTTQAQ 501
             .|:....||...::.:.|:...|          .|...|.||  :.:.:.|..|.|: ..::.|
plant   450 VDEIERITVEAHNQISEAEKRYAN----------ALEDEKLRY--QNDYMESIKKLEE-NWSKNQ 501

  Fly   502 EILAAADLATDDTHQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKEQ 566
            :.|||..||..:.:.|..|....|.:...: ....:.|..:|...:    |....:::...||.|
plant   502 KKLAAERLALGEKNGLDITSNGNRSIAPAL-EEVSELKKLLQKEAQ----SKMAAEEEVNRLKHQ 561

  Fly   567 LSQEMVNSSYVSQRLALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVMKISDQHSQAFVAKLME 631
            |::        .:::..:.:..|..|.:|    |:::|....||.||:..:   |||..
plant   562 LNE--------FKKVEASGNSEIMRLHKM----LENETQQKEKLEGEIATL---HSQLL------ 605

  Fly   632 QMQQQQLLMSKEIQTNLQVIEENNQRHKAMLDSMQEKFATIIDSSLQSVEE--HAKQ--MHKKLE 692
                |..|.:.|.:.||:  :..:::.....||:..:.      .|..:::  :|::  :.:..|
plant   606 ----QLSLTADETRRNLE--QHGSEKTSGARDSLMSQL------RLPQIQDPGNAEKPPVARLFE 658

  Fly   693 QLG---AMSLPDAEE----------LQNLQEELANERALAQQEDALLESMMMQMEQIKNLRSKNS 744
            |:|   .:||.:||:          :.||..|.||::.:.  |...|.|::|.:        ||:
plant   659 QVGLQKILSLLEAEDADVRIHAVKVVANLAAEEANQQQIV--EAGGLTSLLMLL--------KNT 713

  Fly   745 ISMSVH-LNKMEESRLTRNHRIDDIKSGIQDYQKLGIEASQSAQAE--LTSQMEAGM---LCLDQ 803
            ...::| :.....:.|..|....::   |.|...:|:.:|.:|.||  .|.:|.||.   ||.:.
plant   714 EDETIHRVAAGAIANLAMNETNQEL---IMDQGGIGLLSSTAANAEDPQTLRMVAGAIANLCGND 775

  Fly   804 ----------------GVANCS----MLQVHMKNLN-QKYEKETNENVGSVR-----VHHNQVEI 842
                            |:..|.    :.||.....| .|.|...:...|:.|     :....:..
plant   776 KLQTKLRSEGGIAALLGMVRCGHPDVLAQVARGIANFAKCESRASTQAGTKRGKSLLIEDGALSW 840

  Fly   843 ICQESKQQLEAVQEKTEVNLEQMVDARQQLITEDRQRFIGHATVATDLVQESNRQFSEHAEHQRQ 907
            |.|.:|.:..|::...|:.|..:..               |...|.::|:|.  ...|.....|.
plant   841 IVQNAKTETAAIRRHIELALCHLAQ---------------HEGNAKEMVKEG--AMWELVRISRD 888

  Fly   908 QLQICEQELVRFQQSELKTYAPTGTTPSKR 937
                |.:|.:|.......|.:||..|..:|
plant   889 ----CSREDIRSLAHRTLTSSPTFLTELRR 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	135/369 (37%)
		SMC_prok_B	<408..728	CDD:274008	71/337 (21%)
		SMC_prok_B	<651..>921	CDD:274008	62/318 (19%)
		Microtub_bind	923..>1004	CDD:464048	5/15 (33%)
ARK3	NP_001184972.1	Kinesin	76..412	CDD:459720	132/352 (38%)
		EnvC	425..>620	CDD:443969	53/249 (21%)
		armadillo repeat	656..687	CDD:293788	7/30 (23%)
		Arm	693..731	CDD:425727	9/47 (19%)
		armadillo repeat	696..729	CDD:293788	7/42 (17%)
		Syo1_like	697..>883	CDD:474028	42/215 (20%)
		armadillo repeat	736..773	CDD:293788	12/39 (31%)
		armadillo repeat	779..811	CDD:293788	4/31 (13%)