Protein Alignment Klp61F and FRA1

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_199593.2
• Gene: FRA1 / 834833
• AraportID: AT5G47820
• Length: 1035
• Species: Arabidopsis thaliana
• Alignment Length: 1132
• Identity: 294/1132 - (25%)
• Similarity: 485/1132 - (42%)
• Gaps: 299/1132 - (26%)

  Fly    19 NIQVYVRVRPLNSRERCIRSAEVVDVV--GPREVVTRHTLDSKLTKKFTFDRSFGPE-SKQCDVY 80
            :::|.|.:|||...||.....:.|.||  .|:..:..|:        ||||..:|.. |...::|
plant    11 SVKVAVHIRPLIGDERIQGCQDCVTVVTGKPQVQIGSHS--------FTFDHVYGSSGSPSTEMY 67

  Fly    81 SVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIPRALSHLFDEL 145
            ....:||::.:..|||.||.||||||:|||:||        .:...|.|..||||:.::.||.::
plant    68 EECAAPLVDGLFQGYNATVLAYGQTGSGKTYTM--------GTGCGDSSQTGIIPQVMNALFTKI 124

  Fly   146 RMM--EVEYTMRISYLELYNEELCDLL--------STDDT--------------TKIRIFDDSTK 186
            ..:  ::|:.:.:|::|::.||:.|||        .|::|              .:||    .|.
plant   125 ETLKQQIEFQIHVSFIEIHKEEVQDLLDPCTVNKSDTNNTGHVGKVAHVPGKPPIQIR----ETS 185

  Fly   187 KGSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVV-HIRE------- 243
            .|.:.:.|..|:.|.:..::...|::|...|.|.:|.||.||||||.:|:|.| .:|:
plant   186 NGVITLAGSTEVSVSTLKEMAACLDQGSVSRATGSTNMNNQSSRSHAIFTITVEQMRKINTDSPE 250

  Fly   244 ----NGIEGEDMLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDR-- 302
                ||...|:.| ..||:||||||||...:.|:: |:|.:|.|:||:.||.||.||:||.|.
plant   251 NGAYNGSLKEEYL-CAKLHLVDLAGSERAKRTGSD-GLRFKEGVHINKGLLALGNVISALGDEKK 313

  Fly   303 ---APHVPYRESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQ 364
               ..|||||:||||||||:||||.::|.:||.|||...:.||||:||:||:||:||:|||.||:
plant   314 RKDGAHVPYRDSKLTRLLQDSLGGNSRTVMIACISPADINAEETLNTLKYANRARNIRNKPVVNR 378

  Fly   365 KLTKKTVLKEYTEEIDKLKRDLMAARDKNGIYLAE-ETYGEITLKLESQNRELNEKMLLLKALKD 428
            ......:|| ..::::.|:.:|  :....|...|| :...|..:.||:.|.||..::...::...
plant   379 DPVSSEMLK-MRQQVEYLQAEL--SLRTGGSSCAEVQALKERIVWLETANEELCRELHEYRSRCP 440

  Fly   429 ELQNKEKIFSEV------------------------SMSLVEKT--------QELKKTEENLLNT 461
            .:::.||.|.::                        :..:||.|        :|.|:.|..||..
plant   441 GVEHSEKDFKDIRADDIVGSVRPDGLKRSLHSIESSNYPMVEATTGDSREIDEEAKEWEHKLLQN 505

  Fly   462 KGTLLLTKKVLTKTKRRYKEKKELVASHMKTEQVLTTQAQEILAAADLATDDTHQLHGTIERRRE 526
            .     ..|.|.:..||.:||:    |.||           :....|.|....|  .|  ::..|
plant   506 S-----MDKELYELNRRLEEKE----SEMK-----------LFDGYDPAALKQH--FG--KKIAE 546

  Fly   527 LDEKIRRSCDQFKDRMQDNLEMIG--GSLNLYQDQQAALKEQLSQEMVNSSYVSQRLALNSSKSI 589
            :::: :||..:.::|:...:|.:.  |.....||..|...:.|..::::       |.......:
plant   547 VEDE-KRSVQEERNRLLAEIENLASDGQAQKLQDVHAQNLKALEAQILD-------LKKKQESQV 603

  Fly   590 EMLKEM-----CAQSLQDQTNLHNKLIGEVMKISDQHSQAFVAKLMEQMQQQQLLMSKEIQTNLQ 649
            ::||:.     .|:.|||:....     :..|:..||.....|   ||.:|.:....||:   ||
plant   604 QLLKQKQKSDDAARRLQDEIQSI-----KAQKVQLQHRMKQEA---EQFRQWKASREKEL---LQ 657

  Fly   650 VIEENN----QRHKAMLDSMQEKFATIIDSSLQSVEEHAKQMHKKLEQL--GAMSLPDAEELQNL 708
            :.:|..    :|||....:.::|..      ||...|.|....|:|::|  ...|.|
plant   658 LRKEGRKSEYERHKLQALNQRQKMV------LQRKTEEAAMATKRLKELLEARKSSP-------- 708

  Fly   709 QEELA-----------NERALAQQEDALLESMMMQMEQIKNLRSKNSISMSVHLNKMEESRLTRN 762
            :|..|           ||::|.:..|..|| :|:.:.::::...|.|     |:.......|...
plant   709 REHSAGTNGFGTNGQTNEKSLQRWLDHELE-VMVNVHEVRHEYEKQS-----HVRAALAEELAVL 767

  Fly   763 HRIDDI----------KSGIQDYQKLGIEASQSAQAELTSQMEAGMLCLDQG--VANCSMLQVHM 815
            .::|:.          |:|......|    |.:|:....|.:| .||.:...  ||..|.|.
plant   768 RQVDEFAVKGLSPPRGKNGFARASSL----SPNARMARISSLE-NMLVISSNSLVAMASQLS--- 824

  Fly   816 KNLNQKYEKETNENVGSVRVHHNQVEIICQESKQQLEAVQEKTEVNLEQMVDARQQLITEDRQRF 880
                   |.|..|...:.|...||:..: .|:|..|:.:       ...:.:.|.||..:|.:
plant   825 -------EAEERERAFTNRGRWNQLRSM-GEAKNLLQYM-------FNSLAETRCQLWEKDVE-- 872

  Fly   881 IGHATVATDLVQESNRQFSE------HAEHQR----QQLQICEQEL----------VRFQQSELK 925
                      ::|...||.|      .:|.:|    ::|::.||.:          |:....:|.
plant   873 ----------IKEMKDQFKEIVGLLRQSELRRKEAEKELKLREQAIATSLGTPPSSVKHVAEDLS 927

  Fly   926 TYAPTGTTPSKRDFVY-----------PRTLVAT------------------------------S 949
            |.:|. |.|:::...:           |...:.|                              |
plant   928 TPSPM-TVPAQKQLKFTPGIANGKVRGPAAFLDTNKKMVPMGQVSMRKLSAVGKQGGRLWRWKRS 991

  Fly   950 PHQEIVR-RYRQELDWSDLDTTATIDE 975
            .||.||: :::.:..|...:...|.||
plant   992 HHQWIVQFKWKWQKPWRLSEWIRTSDE 1018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	149/389 (38%)
		SMC_prok_B	<408..728	CDD:274008	78/375 (21%)
		SMC_prok_B	<651..>921	CDD:274008	64/318 (20%)
		Microtub_bind	923..>1004	CDD:464048	16/95 (17%)
FRA1	NP_199593.2	KISc_KIF4	10..371	CDD:276823	143/381 (38%)
		PRK03918	<384..909	CDD:235175	128/625 (20%)
		GumC	<480..>705	CDD:442439	61/273 (22%)