Protein Alignment Klp61F and MRH2

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001326426.1
• Gene: MRH2 / 824652
• AraportID: AT3G54870
• Length: 1051
• Species: Arabidopsis thaliana
• Alignment Length: 1093
• Identity: 280/1093 - (25%)
• Similarity: 486/1093 - (44%)
• Gaps: 204/1093 - (18%)

  Fly     6 GNTSRQPQKKSNQN------IQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTL--DSKLTK 62
            |...|:.|.|...:      ::|.|||||.|. |..|..|:..|:|..:..:.|..|  ::..::
plant    85 GTPVRRSQSKDFDDDNDPGRVRVSVRVRPRNG-EELISDADFADLVELQPEIKRLKLRKNNWNSE 148

  Fly    63 KFTFDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWED 127
            .:.||..|...:.|..||..|..|::|.||:|||.|:.||||||||||:| ||      |...:|
plant   149 SYKFDEVFTDTASQKRVYEGVAKPVVEGVLSGYNGTIMAYGQTGTGKTYT-VG------KIGKDD 206

  Fly   128 DSDIGIIPRALSHLFDELRMMEVEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVII 192
            .::.||:.|||..:.  |.......::.||||:||.|.:.|||: .:...|.|.:|: |.|.|.:
plant   207 AAERGIMVRALEDIL--LNASSASISVEISYLQLYMETIQDLLA-PEKNNISINEDA-KTGEVSV 267

  Fly   193 QGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIREN-----------GI 246
            .|...:.:...|...::|:.|:..|..|.|.||.:|||||.:.::.|....|           |.
plant   268 PGATVVNIQDLDHFLQVLQVGETNRHAANTKMNTESSRSHAILTVYVRRAMNEKTEKAKPESLGD 332

  Fly   247 EGEDMLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDRAPHVPYRES 311
            :....::..||.:|||||||.::|:|.: |..:.|...||.||.:||:.|.||.:.:.|:|.|:|
plant   333 KAIPRVRKSKLLIVDLAGSERINKSGTD-GHMIEEAKFINLSLTSLGKCINALAEGSSHIPTRDS 396

  Fly   312 KLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYT 376
            ||||||::|.||..:||:|.||.|..:...||.||:.:..||..|.|..::.::...:::.::..
plant   397 KLTRLLRDSFGGSARTSLIITIGPSARYHAETTSTIMFGQRAMKIVNMVKLKEEFDYESLCRKLE 461

  Fly   377 EEIDKLKRDLMAARDKNGIYLAEETYGEITLKLESQNRELN-EKMLLLKALKDELQNKEKIFSEV 440
            .::|.|                       |.::|.||:..| ||..|.|.|: |.:|.   |:|.
plant   462 TQVDHL-----------------------TAEVERQNKLRNSEKHELEKRLR-ECENS---FAEA 499

  Fly   441 SMSLVEKTQELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKKEL-----VASHMKTEQVLTTQA 500
            ..:.|.:::.|:|.     ||:  |.|:.|.|.|..:..|::.:|     :...||.:.....|.
plant   500 EKNAVTRSKFLEKE-----NTR--LELSMKELLKDLQLQKDQCDLMHDKAIQLEMKLKNTKQQQL 557

  Fly   501 QEILAAADLATDDTHQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKE 565
            :.....|.||  ||.|::     .:::.|.::|..|: :.|..:....:....|:...||.::.|
plant   558 ENSAYEAKLA--DTSQVY-----EKKIAELVQRVEDE-QARSTNAEHQLTEMKNILSKQQKSIHE 614

  Fly   566 QLSQEMVNSSYVSQRLALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVM-KISDQHSQAFVAKL 629
               ||..|..|  ||                  .|.:.|:.:...|.|:. |:..:::::..|:
plant   615 ---QEKGNYQY--QR------------------ELAETTHTYESKIAELQKKLEGENARSNAAE- 655

  Fly   630 MEQMQQQQLLMSKEIQTNLQVIEENNQRH---KAMLDSMQEKFATIIDSSLQSVEEHAKQMHKKL 691
             :|::|.:.|:|     :.|||.:.|:..   |..|:.:.:.:.:.:| .||:|:.....:.::.
plant   656 -DQLRQMKRLIS-----DRQVISQENEEANELKIKLEELSQMYESTVD-ELQTVKLDYDDLLQQK 713

  Fly   692 EQLGAMSLPDAEELQNLQEELANERALAQQEDALLESMMMQMEQIKNLRSKNSISMSVHLNKMEE 756
            |:||       ||:::::|.|..|....:|    :||.:.:::  ||||...        |.:||
plant   714 EKLG-------EEVRDMKERLLLEEKQRKQ----MESELSKLK--KNLRESE--------NVVEE 757

  Fly   757 SRLTRNHRIDDIKSG-IQDYQKLGIEASQSAQAELTSQMEA-GMLCLDQGVANCSMLQVHMKNLN 819
            .|..:    :|:..| .:...:.|.:.||..:..|:.|... ..||.:.|:         .|.|.
plant   758 KRYMK----EDLSKGSAESGAQTGSQRSQGLKKSLSGQRATMARLCEEVGI---------QKILQ 809

  Fly   820 QKYEKETNENVGSVRVHHNQVEIICQESKQQLEAVQEKTEVNLEQMVDARQQ------------- 871
            ....::....:.:|:|..|    :..|...|::.|:|.....|..:|.:.|.
plant   810 LIKSEDLEVQIQAVKVVAN----LAAEEANQVKIVEEGGVEALLMLVQSSQNSTILRVASGAIAN 870

  Fly   872 -LITEDRQRFI---GHATVATDLVQESNRQFSEHAEHQRQQL------QIC--EQELVRFQQSE- 923
             .:.|..|..|   |.|.:...:|.:::       :.|..::      .:|  |:.|...::.|
plant   871 LAMNEKSQDLIMNKGGAQLLAKMVTKTD-------DPQTLRMVAGALANLCGNEKFLKLLKEEEG 928

  Fly   924 ---LKTYAPTGTTPSKRDFVYPRTLVATSPHQEIVRRYRQ---------ELDWSDLDTTATIDEC 976
               |.|.|.:|...............|....:||::..|:         .|:|  |.:.:.||..
plant   929 IKGLLTMAQSGNIDIIAQVARGMANFAKCETREIMQGRRKGRSLLLEEGVLEW--LTSNSHIDSA 991

  Fly   977 SEGEH-DVSM-HSVQELSETETIMNSTPIEPVDGVTVKRGCGTTRNSNSNALK 1027
            |...| :::: |..|..........:..:..:..::|:......|:.....||
plant   992 STQRHIELALCHLAQNEENANDFKRTGSVTEIVRISVESSRDDIRSLAKKILK 1044

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	132/366 (36%)
		SMC_prok_B	<408..728	CDD:274008	77/329 (23%)
		SMC_prok_B	<651..>921	CDD:274008	59/299 (20%)
		Microtub_bind	923..>1004	CDD:464048	18/95 (19%)
MRH2	NP_001326426.1	KISc	121..439	CDD:276812	120/329 (36%)
		Smc	<476..>757	CDD:440809	81/351 (23%)
		SRP1	718..>914	CDD:227396	45/233 (19%)
		armadillo repeat	804..829	CDD:293788	5/37 (14%)
		armadillo repeat	836..873	CDD:293788	6/36 (17%)
		Arm	839..873	CDD:425727	5/33 (15%)
		armadillo repeat	878..913	CDD:293788	6/41 (15%)