Protein Alignment Klp61F and KINESIN-12B

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_189009.2
• Gene: KINESIN-12B / 821947
• AraportID: AT3G23670
• Length: 1313
• Species: Arabidopsis thaliana
• Alignment Length: 1125
• Identity: 270/1125 - (24%)
• Similarity: 459/1125 - (40%)
• Gaps: 269/1125 - (23%)

  Fly    16 SNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSKLT---KKFTFDRSFGPESKQC 77
            |:..::|.||::|.:..|.             .|::.:...:..||   :.||||....|||.|.
plant    93 SDSGVKVIVRMKPPSKGEE-------------EEMIVKKISNDALTINEQTFTFDSIADPESTQD 144

  Fly    78 DVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIPRALSHLF 142
            :::.:|.:||:|..|.|:|.:||||||||:|||:||.|.....|:.....|.. |:.||....||
plant   145 EIFQLVGAPLVENCLAGFNSSVFAYGQTGSGKTYTMWGPANGLLEEHLSGDQR-GLTPRVFELLF 208

  Fly   143 DEL-------RMMEVEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVIIQGLEEIPV 200
            ..|       ...:::|..|.|:||:|||::.|||  |.:.|..:..:..|.| |.::.|.|..|
plant   209 ARLSEEQAKHAERQLKYQCRCSFLEIYNEQITDLL--DPSLKNLMIREDVKSG-VYVENLTEEYV 270

  Fly   201 HSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGI-EGEDMLKIGKLNLVDLAG 264
            .:..|:.|||.||...|:|..|.:||:|||||.||:.||......: :|....|..::|||||||
plant   271 KNLKDLSKLLVKGLANRRTGATSVNAESSRSHCVFTCVVESHCKSVADGLSSFKTSRINLVDLAG 335

  Fly   265 SENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVD-----RAPHVPYRESKLTRLLQESLGGR 324
            ||. .|.....|.|::|..|||:||..||.:|..|.:     :..|:|||:|:||.||||||||.
plant   336 SER-QKLTGAAGDRLKEAGNINRSLSQLGNLINILAEISQTGKQRHIPYRDSRLTFLLQESLGGN 399

  Fly   325 TKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTK-----KTVLKEYTEEIDKLK- 383
            .|.:::..:||......||.|||.:|.|||.||||..||:.:..     :.|:::..:|:.::|
plant   400 AKLAMVCAVSPSQSCRSETFSTLRFAQRAKAIQNKAIVNEVMQDDVNFLREVIRQLRDELQRVKD 464

  Fly   384 --------------------RDLMAAR-------------DKNG---IYLAEETYGEITLKL--- 409
                                |.|...|             |.:|   :.:.||....:..::
plant   465 DKGNNPTNPNAAYTTSWNARRSLSLLRSFGLGHPKSLPNGDDDGDTEMEIDEEAVERLCAQMGLS 529

  Fly   410 ---ESQNRELN--EKM---LLLKALKDELQNKEKIFSEVSMSLVEKTQELKKTEENLLNTKGTLL 466
               |..|:|::  ||:   |....||||..|...:.|..:.. |.......:||.|...|...|.
plant   530 PPAEDNNQEMSRVEKINSSLQTVVLKDESYNNSHLKSSEATD-VNMEDACCQTENNGSETDNALT 593

  Fly   467 LTKKV----------LTKTKRRYKEKKELVASHMKTEQVLTTQAQEILAAADLATDDTHQLHGTI 521
            :.:.:          :|.:............|..|.|.:  ...|:::..||::.
plant   594 VAETMDDGSSVQPDSITNSLHSCISDTNQGNSPSKAENI--PSCQDLVIEADVSA---------- 646

  Fly   522 ERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAAL----KEQLSQEMVNS--SYVSQR 580
                     |....|...:..|.::..:...|::.....:.:    .|..|.::.||  |..:..
plant   647 ---------IVSVADTSNNTEQVSVNPVSPCLSVAPVSVSPVLIPPTESASPKIRNSRKSLRTTS 702

  Fly   581 LALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVMKISDQHSQAFVAKLMEQMQQQQLLMSKEIQ 645
            ::..|.|.||...::..:.::....:..:::.....:|.:.|:||      .:..:||..|
plant   703 MSTASQKDIERANQLTPEVVEPSPAMSTEVLNLYSALSTKKSEAF------PVPTRQLAAS---- 757

  Fly   646 TNLQVIEENNQRHKAM--LDSMQEKFA---TIIDSSLQSVEEHAKQMHKKLEQLGAMSLPDAEEL 705
                       .|:.|  |||.::..|   :....|.:::|.....:..|.: :|..:.|.|:|:
plant   758 -----------LHRGMKLLDSYRQSTALRRSTFRLSYKALECKPSTVLSKAD-VGVQTYPQADEI 810

  Fly   706 --QNLQEELANERALAQQEDA--LLESMMMQMEQIKNLRSKNSISMSVHLNKMEESRLTRNHRID 766
              .|.:|.|.:......:.||  :.::..:|:..|.|  |:.|...:..:.|..|..|..:.|
plant   811 AEDNSKEVLCSRCKCRAECDAQEISDTSNLQLVPIDN--SEGSEKSNFQVPKAVEKVLAGSIR-- 871

  Fly   767 DIKSGIQDYQKLGIEASQSAQAELTSQMEAGMLCLDQGVANCSMLQVHMKNLNQKYEKETNENVG 831
                     :::.:|...:.||...||:.             .::|.:      |:|:|.|..:|
plant   872 ---------REMAMEEFCTKQASEISQLN-------------RLVQQY------KHERECNAIIG 908

  Fly   832 SVRVHHNQVEIICQESKQQLEAVQEKTEVNLEQMVD---ARQQLITEDRQRFIGHATVATDLVQE 893
            ..|                     |...|.||.::|   ::...:.|:....:....:..|:
plant   909 QTR---------------------EDKIVRLESLMDGVLSKDDFLDEEFASLMHEHKLLKDM--- 949

  Fly   894 SNRQFSEHAE--HQRQQLQICEQELVRFQ-------------------QSELKTYAPTGTTPSKR 937
                :..|.|  ..|.:|:..::||..|:                   :::|:.|..:..|.::|
plant   950 ----YENHPEVLQTRIELKRVQEELESFKNFYGDMGEREVLLEEIHDLKAQLQCYTDSSLTSARR 1010

  Fly   938 DFVYPRTLVATSPH---------------------QEIVRRYRQELDW--------SDLDTTATI 973
            .....:...|..|:                     ||.:|....|.:|        ::|||...:
plant  1011 RGSLLKLTYACDPNQAPQLNTIPESVDEGPEKTLEQERLRWTEAESNWISLAEELRTELDTNRLL 1075

  Fly   974 DECSEGEHDVSMHSVQELSE 993
            .|..:.|.|......:||:|
plant  1076 MEKQKRELDTEKRCAEELTE 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	141/363 (39%)
		SMC_prok_B	<408..728	CDD:274008	63/355 (18%)
		SMC_prok_B	<651..>921	CDD:274008	53/302 (18%)
		Microtub_bind	923..>1004	CDD:464048	20/100 (20%)
KINESIN-12B	NP_189009.2	PLN03188	1..1313	CDD:215621	270/1125 (24%)