Protein Alignment Klp61F and POK2

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_188535.4
• Gene: POK2 / 821439
• AraportID: AT3G19050
• Length: 2771
• Species: Arabidopsis thaliana
• Alignment Length: 1156
• Identity: 301/1156 - (26%)
• Similarity: 515/1156 - (44%)
• Gaps: 293/1156 - (25%)

  Fly    17 NQNIQVYVRVRPLNSRE-------RCIR--SAEVVDVVGPREVVTRHTLDSKLTKKFTFDRSFGP 72
            :.|:|:.:|||||||.|       ||::  |::.|..:||.|.            :|.||.....
plant   191 DHNVQILIRVRPLNSMERSINGYNRCLKQESSQCVAWIGPPET------------RFQFDHVACE 243

  Fly    73 ESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIPRA 137
            ...|..::.|...|::|..|:|||..:|||||||:|||:||:| |..:|:  ::...:.|::||.
plant   244 TIDQETLFRVAGLPMVENCLSGYNSCIFAYGQTGSGKTYTMLG-EVGDLE--FKPSPNRGMMPRI 305

  Fly   138 LSHLFDELRMME-------VEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVIIQGL 195
            ...||..::..|       ::|..:.|:||:|||::.|||. ..:|.:::.:|.  |..|.::.|
plant   306 FEFLFARIQAEEESRRDERLKYNCKCSFLEIYNEQITDLLE-PSSTNLQLREDI--KSGVYVENL 367

  Fly   196 EEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGEDMLKIGKLNLV 260
            .|..|.|..|:..|:.:|...|:...|.||.:|||||:||:.|:..|.......:| :..:||||
plant   368 TECEVQSVQDILGLITQGSLNRRVGATNMNRESSRSHSVFTCVIESRWEKDSTANM-RFARLNLV 431

  Fly   261 DLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVD----RAPHVPYRESKLTRLLQESL 321
            ||||||....:|.| |.|::|..:||:||.|||.||..|||    :..|:|||:|:||.|||:||
plant   432 DLAGSERQKTSGAE-GDRLKEAASINKSLSTLGHVIMVLVDVANGKPRHIPYRDSRLTFLLQDSL 495

  Fly   322 GGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQK-----LTKKTVLKEYTEEIDK 381
            ||.:||.|||..||......|||:||::|.|||.|||...||:.     |..:..::...||:..
plant   496 GGNSKTMIIANASPSVSCAAETLNTLKFAQRAKLIQNNAVVNEDSNEDVLELRRQIRLLKEELSL 560

  Fly   382 LKRDLMA---------------------------ARDKNGIYLAEETYG------------EITL 407
            |||..::                           .:.:.|..|..|:.|            ||||
plant   561 LKRQNISRALSFGSATANFAESQVDSPSSVMHETGQQQAGNLLVYESGGCVRMSRKQLKSLEITL 625

  Fly   408 ---------------KLESQNRELNEKM-----------LLLKALKDELQNKEKIF-SEVSMS-- 443
                           |||::...||..:           ::|:..:|::|..|.:. :.:|..
plant   626 AGSLRREHVADASIKKLEAEIEHLNRLVRQREEDTRSTKMMLRFREDKIQRLESLLGNHISADSF 690

  Fly   444 LVEKTQELKKTEENLLNTKGTLL---------LTKKVLTKTK-----RRYKE-----KKELVASH 489
            |:|        |.|:|:.:..||         ||:..|...:     ||::|     ::|::...
plant   691 LLE--------ENNVLSEEIQLLQAKIDKNPELTRFALENIRLLDQLRRFQEFYEEGEREILLGE 747

  Fly   490 MKTEQVLTTQAQEIL---AAADLATDDTHQLHGTIERRRE---LDEKIRRSCDQFKDRMQDNLEM 548
            :..   |..|..:.|   :......||..:..|.....:|   |.|:::::|.:        ||.
plant   748 VSN---LRNQLFQFLDENSDWQKHVDDGIEPQGASRMSKENCSLQEELKKTCYE--------LEK 801

  Fly   549 IGGSLNLYQDQQAALKEQLS--QEMVNS---------SYVSQRLALNSSKSIEMLKEM-CAQSLQ 601
            ...:|....::.|.|..:::  |.||:.         |.|:::.||..:::.|..:.: |.|:..
plant   802 CRSNLGSCLEENAKLSREINDLQAMVSDIRACTPDEHSSVNKQKALLGTQNFEPHETLACEQANY 866

  Fly   602 DQTNLHNKLIGEVMKI---------SDQHSQAFVAKL-MEQMQQQQLLMSKEIQTNLQVIEENNQ 656
            .:..:..:|..:|.||         .|..:||...|. :|.::.|.||:||: |.|  |..|..:
plant   867 VEEIIKLQLDLDVQKIILDEERTLRGDTEAQAVRLKFDIEVLKDQLLLISKQ-QKN--VYSELGE 928

  Fly   657 RHKAMLDSMQEKFATIIDSS--LQSVEEHAKQMHKKLEQLGAMSLPDAEELQNLQEELANERALA 719
            . |:.:.:::.:...:|..:  |:.::|:..::.||.|    :.:|..:..|  .:|..:..|..
plant   929 T-KSAVAALESQNIILIQEAVELRRIKENYFELLKKQE----LDIPAMKSKQ--CDEFKDNPAED 986

  Fly   720 QQEDALLESMMMQMEQIK--NLRSKNSISMSVHLNKMEESRLTRNHRIDDIKSGIQDYQKLGIEA 782
            .:.|...:.|...:|:.|  |:..|:.|:          |:...:..:|::           .:.
plant   987 SEIDTKFKKMQASLEKAKRLNMLYKSDIA----------SKACGDEEMDEV-----------CKQ 1030

  Fly   783 SQSAQAELTSQMEAGMLCLDQGVANCSMLQVHMKNLNQKYEKETNENVGSVRVHHNQVEIICQES 847
            :::|.||:       ::||.      :.|:|..|.:|....||        .|...||||:
plant  1031 AEAATAEV-------IVCLQ------NELEVLQKEVNDFQSKE--------NVTEKQVEIL---- 1070

  Fly   848 KQQLEAVQEK---TEVNLEQMVDARQQLITEDRQRFIGHATVATDLVQESNRQFSEHAEHQRQQL 909
            :.|:|.:|:|   |.::.||:   ::||..:|.:..|    ::.::                 :|
plant  1071 ETQMEELQDKLRDTTMDNEQL---QEQLRGKDMELLI----ISNEM-----------------EL 1111

  Fly   910 QICEQELVRFQQSELKTYA------PTGTTPSKRDFVYPRT--LVATSPHQEIV----------- 955
            ...|.|.:....:|..|.|      .:|:.|.||.::..:.  |:.|...:|::
plant  1112 LTSELEEILLNGNEGLTDACYQADLISGSLPDKRIWISEQVGGLIRTLSERELMIEDLESCLEDA 1176

  Fly   956 --RRYRQELDWSDLDTTATI------DECSEGEHDVSMHSVQELSETETIM 998
              :|...|.....|...|.:      .|..|.|.||.:...|..::||||:
plant  1177 NKKRCDIESMLKSLKGAAIVMNEAHQREFEEKETDVLLLKSQLCTKTETIL 1227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	146/367 (40%)
		SMC_prok_B	<408..728	CDD:274008	79/382 (21%)
		SMC_prok_B	<651..>921	CDD:274008	51/276 (18%)
		Microtub_bind	923..>1004	CDD:464048	24/103 (23%)
POK2	NP_188535.4	Motor_domain	192..540	CDD:473979	146/367 (40%)
		PLN03188	<614..>763	CDD:215621	31/159 (19%)
		SMC_prok_B	615..>1344	CDD:274008	145/712 (20%)
		SMC_N	<1262..1598	CDD:481474
		SMC_prok_B	<1674..2384	CDD:274008
		Smc	<2131..>2674	CDD:440809