Protein Alignment Klp61F and AT3G12020

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001189866.1
• Gene: AT3G12020 / 820376
• AraportID: AT3G12020
• Length: 1044
• Species: Arabidopsis thaliana
• Alignment Length: 1076
• Identity: 286/1076 - (26%)
• Similarity: 485/1076 - (45%)
• Gaps: 225/1076 - (20%)

  Fly    11 QPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSKLTKKFTFDRSFGPESK 75
            |..::|.:|:.|.||.|||:.||  ||..|.|......|.:.|:  :...|..:.:||.|||.:.
plant    61 QTAQRSKENVTVTVRFRPLSPRE--IRQGEEVAWYADGETIVRN--EHNPTIAYAYDRVFGPTTT 121

  Fly    76 QCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIPRALSH 140
            ..:||.:....::...:.|.|.|:||||.|.:||||||.|           |....||||.|:..
plant   122 TRNVYDIAAHHVVNGAMEGINGTIFAYGVTSSGKTHTMHG-----------DQRSPGIIPLAVKD 175

  Fly   141 LFDELR-MMEVEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVIIQGLEEIPVHSKD 204
            .|..:: ....|:.:||||:|:|||.:.|||:... ..:||.:|  |:|: .::|::|..|.|..
plant   176 AFSIIQETPNREFLLRISYMEIYNEVVNDLLNPAG-HNLRIRED--KQGT-FVEGIKEEVVLSPA 236

  Fly   205 DVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGE-DMLKIGKLNLVDLAGSENV 268
            ....|:..|:|:|...:|..|..||||||:|::.:.....|.:.: :.:.:.:||||||||||:
plant   237 HALSLIAAGEEQRHVGSTNFNLLSSRSHTIFTLTIESSPLGDKSKGEAVHLSQLNLVDLAGSES- 300

  Fly   269 SKAGNEKGIRVRETVNINQSLLTLGRVITALVD-RAPHVPYRESKLTRLLQESLGGRTKTSIIAT 332
            ||. ...|:|.:|...||:||||||.||:.|.| ||.|||||:|||||:||.||.|..:.|:|.|
plant   301 SKV-ETSGVRRKEGSYINKSLLTLGTVISKLTDVRASHVPYRDSKLTRILQSSLSGHDRVSLICT 364

  Fly   333 ISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEIDKLKRDLMAARDKNGIYL 397
            ::|.....|||.:||::|||||:|:.:.|.|:.:.:|:::|:|..||.:||.:|
plant   365 VTPASSSSEETHNTLKFAHRAKHIEIQAEQNKIIDEKSLIKKYQREIRQLKEEL----------- 418

  Fly   398 AEETYGEITLKLESQNRELNEKMLLLKALKD---ELQNKEKIFSEVSMSLVEKTQELKKTEENLL 459
             |:...||....:.::...::.:||.:.|:|   :||::.:...|...:|:.:.|.
plant   419 -EQLKQEIVPVPQLKDIGADDIVLLKQKLEDGQVKLQSRLEEEEEAKAALLSRIQR--------- 473

  Fly   460 NTKGTLLLTKKVLTKTK--------RRYKEKKELVASHMKTEQVLTTQAQEILAAADLATDDTHQ 516
                   |||.:|..||        .|:..::.    |...|:.|   |.......|:..|:...
plant   474 -------LTKLILVSTKNPQASRLPHRFNPRRR----HSFGEEEL---AYLPYKRRDMMDDEQLD 524

  Fly   517 LHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLY----QDQQAALKEQLSQEMVNSS-- 575
            |:.::|...|:.:...|  ::.|.|..       |.||..    :|..::..:|.|....||:
plant   525 LYVSVEGNHEIRDNAYR--EEKKTRKH-------GLLNWLKPKKRDHSSSASDQSSVVKSNSTPS 580

  Fly   576 ---------YVSQRLALNSSKSIEMLKE--MCAQSLQDQTNLHNKLIGEVM-KISDQHSQAFVAK 628
                     :...||: ..|..:|.|.|  ...::|:|.:  |...|.|.. |:||:
plant   581 TPQGGGSHLHTESRLS-EGSPLMEQLSEPREDREALEDSS--HEMEIPETSNKMSDE-------- 634

  Fly   629 LMEQMQQQQLLMSKEIQTNLQVI-------------EENNQRHKAMLDSMQEKFATIIDSSLQSV 680
             ::.:::|:.::|:|....|..:             ||.|:..|.:.|.::.|...|.....| :
plant   635 -LDLLREQKKILSEEAALQLSSLKRMSDEAAKSPQNEEINEEIKVLNDDIKAKNDQIATLERQ-I 697

  Fly   681 EEHAKQMHKKLEQLGAMSLPDAEELQNLQEELANERALAQQEDALLESMMMQMEQI-KNLRSKNS 744
            .:.....|:.|::...|     :.:..|:::| ||::...:...|.  :.||...| ..:|...:
plant   698 MDFVMTSHEALDKSDIM-----QAVAELRDQL-NEKSFELEVIELF--LFMQFFFIYAEVRDGFA 754

  Fly   745 IS-----------MSVHLNKMEESRLTRNHRIDDIKSGIQDYQKLGIEASQSAQAELTSQMEAGM 798
            |:           :|.:|||:....:.:           ..|.|        .|..||.::   |
plant   755 IAWIRLFILAQYYLSSYLNKVSSVYIIK-----------YQYSK--------RQTILTMKL---M 797

  Fly   799 LCLDQGVANCSMLQVHMKNLNQKYEKETNENVGSVRVHHNQVEIICQESKQQLEAVQEKTEVNLE 863
            :|......:.|.|||...: |:..::..||......|...:|..:.|:..:.||..|......|:
plant   798 VCSTLFSHSSSCLQVKAAD-NRIIQQTLNEKTCECEVLQEEVANLKQQLSEALELAQGTKIKELK 861

  Fly   864 QMVDARQQLITEDRQRFIGHATVATDLVQESNRQFSEHAEHQR-------QQLQICEQELVRF-- 919
            |  ||::  ::|.:::           ::..||:.:|.:.:.:       .:|:...:|:.:.
plant   862 Q--DAKE--LSESKEQ-----------LELRNRKLAEESSYAKGLASAAAVELKALSEEVAKLMN 911

  Fly   920 -----------QQSELKTYAPTGTTPSKRDFVYPRTLVA----TSPHQEIVRRYR----QELDWS 965
                       |:|.:.....||||.:.|:.....:|..    .||..|:.|..|    :||.:
plant   912 QNERLAAELATQKSPIAQRNKTGTTTNVRNNGRRESLAKRQEHDSPSMELKRELRMSKERELSY- 975

  Fly   966 DLDTTATIDECSEGEHDVSMHSVQELSETETIMNST 1001
                     |.:.||.:      |..:|.|.|:..|
plant   976 ---------EAALGEKE------QREAELERILEET 996

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	141/350 (40%)
		SMC_prok_B	<408..728	CDD:274008	70/361 (19%)
		SMC_prok_B	<651..>921	CDD:274008	55/314 (18%)
		Microtub_bind	923..>1004	CDD:464048	21/87 (24%)
AT3G12020	NP_001189866.1	KISc_CENP_E	69..388	CDD:276825	138/339 (41%)
		SMC_prok_B	<372..>1041	CDD:274008	156/744 (21%)