Protein Alignment Klp61F and si:dkey-26i13.8

DIOPT Version :9

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: XP_001337836.4
• Gene: si:dkey-26i13.8 / 797363
• ZFINID: ZDB-GENE-090312-134
• Length: 991
• Species: Danio rerio
• Alignment Length: 1111
• Identity: 271/1111 - (24%)
• Similarity: 477/1111 - (42%)
• Gaps: 223/1111 - (20%)

  Fly    12 PQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSKLT--------------- 61
            |.:..:..:.|.:|:||||..|           :.....:..|.:|:::.
Zfish     5 PGEWMDHQLTVALRIRPLNEAE-----------IEEGATIVAHKIDNQMVVLMDPCEDSDNVLRA 58

  Fly    62 -----KKFTFDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAEL 121
                 |.:.||.:|...:.|.|||......||:.|:.|||.||||||.||.||||||:|.
Zfish    59 HRSREKTYMFDLAFDYTATQEDVYVATTKNLIDGVIAGYNATVFAYGPTGAGKTHTMLGL----- 118

  Fly   122 KSSWEDDSDIGIIPRALSHLFDELR--MMEVEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDS 184
                  ||:.||..|.|:.||..:.  ..:::.::.:||:|:|||.:.|||: ..:..:.:.:|.
Zfish   119 ------DSEPGIYIRTLNDLFRAIEDSTEDLDCSVYMSYIEIYNEMIRDLLN-PSSGYLELREDG 176

  Fly   185 TKKGSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGE 249
              ||.:.|.|:.|....:..::..||.||.::|...:|..|..|||||.:..:.|..:....:..
Zfish   177 --KGEIRIAGITEFSTCNAKEIMALLTKGNKQRTQESTAANKTSSRSHAILQVTVKQKSRVKDIN 239

  Fly   250 DMLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDR----APHVPYRE 310
            :.:::|||.:|||||:|..|:..| :|.|::|..:||:|||.|...|.||.::    |..|.||:
Zfish   240 EEVRVGKLFMVDLAGTERASQTQN-RGKRMKEGAHINRSLLALANCINALSEKGGKGAQFVNYRD 303

  Fly   311 SKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTV-LKE 374
            |||||||:::|||.::|.:|..|||...:.||:.:||.||.:||||:.|  |.:.|...:. |.:
Zfish   304 SKLTRLLKDALGGNSRTVMITHISPASSNFEESRNTLVYADKAKNIRTK--VKRNLMNVSYHLAQ 366

  Fly   375 YTEEIDKLKRDLMAARDKNGIYLAEETYGE----ITLKLESQNRELNEKML----LLKALKDELQ 431
            ||..|..|:.::...|.|......::..||    ..::.|.|.....|..|    ||.|.::::
Zfish   367 YTRIIADLRSEIERLRAKIDQQSQDQLKGEKADIRNIQAEVQQYSHGEMALLQEQLLSAFREQM- 430

  Fly   432 NKEKIFSEVSMSLVEKTQELKKTEENL-LNTKGTLLLTKKVLTKTKRRYKEKKELVASHMKT--- 492
                   |:..||:    ||:.....| ::|...||..........|..:||.||......|
Zfish   431 -------EIRRSLM----ELENCNMELHIDTSRHLLTISDWERDRARARREKDELSGQKKHTDKE 484

  Fly   493 --EQVLTTQAQEILAAADLATDDTHQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNL 555
              ::.:..:.|.:.||.:.......:...|:|.:|||:||:                     ||:
Zfish   485 EEQESMPEEPQYVTAAREEIGPLLAEQRKTMELKRELEEKL---------------------LNM 528

  Fly   556 YQDQQAALKEQLSQEMVNSSYVSQRLALNSSKSIEMLKEMC-AQSLQ-DQTNLHNKLI--GEVMK 616
                  .||....:|:     :.:|::....:.|.||  :| ...|: ::|.:.:.::  ..|::
Zfish   529 ------KLKSSKIEEL-----LPKRISNTEQRDILML--LCKVHELELEKTEIQSAVLCKENVLR 580

  Fly   617 ISDQHSQAFVAKLMEQMQQQQLLMSKEIQTNLQVIEENNQRHKAMLDSMQEKFAT--------II 673
            ..|     |:   :::.:||:.|....|.....:||:..   ..:.:.:||.::.        ||
Zfish   581 TKD-----FI---IQRHEQQRTLCDDIIHQQKMLIEDQG---LCVPEGLQELYSLYFGELSDGII 634

  Fly   674 DSSLQ-----SVEEHAKQMHKKLEQLGAMSLPDAEELQN-----LQEELANERALAQQEDALLES 728
            |..|.     :...:|:|:  :|:.:..:...|..|..|     |.:...:..:.....|:....
Zfish   635 DQILNLHTFTTNNLNARQL--RLDVISNLEEADKAEQSNVKFSPLDKHPRDSSSSGLDYDSDTNR 697

  Fly   729 MMMQMEQIKNLRSKNSISMSVHLNK---MEESR---LTRNHRIDDIKSGIQDYQKLGIEASQ--- 784
            :...:.:||..|..:|.|....:.|   :::|.   .|.:...|.::..:.|.:.:.:.|::
Zfish   698 VFKSLSKIKPRRQHHSSSSQTLMRKVCAVKDSTPICPTESVSPDTLREIVSDTKSISVIAAKRRS 762

  Fly   785 SAQAELTSQMEAGMLCLDQGVANCSMLQVHMKNLNQKYEKETNENVGSVRVHHNQVEIICQESKQ 849
            ..||:..|:| |||     |:|......|.|.:|......|:.|...|.:.|...     .:|||
Zfish   763 RLQAKSNSRM-AGM-----GLAAGLKSSVSMDSLVSTLPDESAEVRRSHQRHGGS-----SQSKQ 816

  Fly   850 QLEAVQEKTEVNLEQM-------VDARQQLITEDRQRFIGHATV-----------ATDLVQESNR 896
            ..:..:.:||:..:|.       .:|.::.:.:.||....:..:           |.:::|..|.
Zfish   817 DPKRTEGRTELPEKQQHKKRSRSFEASKRQVQKPRQNASRYPALESISDNHLVRPALNIIQPLNG 881

  Fly   897 QFSEHAEHQRQQLQICEQEL---VRFQQSELKTYAPTGTTPSKRDFVYPRTLVATSPHQEIVRRY 958
            ..:..|.....:::|.....   |:||:.|::     ||.||             :.||:
Zfish   882 GPANPATPPVAKVKIPVSHFTGEVQFQKLEIR-----GTPPS-------------TIHQK----- 923

  Fly   959 RQELDWSDLDTTATIDECSEGEHDVSMHS--VQELSETETIMNSTPIEPVDGVTVKRGCGTTRNS 1021
                 .||......:.:...|:.||...|  :|:....:...|..|.:.......::  ..||..
Zfish   924 -----HSDTKRAQAVYKRQRGQGDVCYPSSLLQQAGNYKKSTNENPKQKAMADVNRK--NETRQR 981

  Fly  1022 NSNALK 1027
            |.:|:|
Zfish   982 NKHAVK 987

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	128/373 (34%)
		Kinesin	25..356	CDD:278646	123/356 (35%)
		Microtub_bind	923..>1009	CDD:290642	16/87 (18%)
si:dkey-26i13.8	XP_001337836.4	KISc	12..356	CDD:214526	128/371 (35%)
		KISc_KIP3_like	12..349	CDD:276821	124/362 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910