Protein Alignment Klp61F and Stard9

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: XP_017447698.1
• Gene: Stard9 / 691920
• RGDID: 1593360
• Length: 4604
• Species: Rattus norvegicus
• Alignment Length: 1264
• Identity: 308/1264 - (24%)
• Similarity: 492/1264 - (38%)
• Gaps: 322/1264 - (25%)

  Fly    19 NIQVYVRVRPLNSRE-----RCIRSAEVVDVVGP-REVVTRHTLDS-----KLTKKFTFDR---S 69
            |:||.||||||:.||     |.|  .||.|.|.. |.|.....|:|     :....|.||.   |
  Rat     3 NVQVAVRVRPLSKRETKEGGRII--VEVDDKVAKVRNVKVNSRLESFGDTREKVVAFGFDYCYWS 65

  Fly    70 FGPESKQCDVYSVVVSPLIEEVLN----GYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSD 130
            ..||........||...|..|||:    |||..:|||||||:|||:||:|.           .:.
  Rat    66 VNPEDPHYASQEVVFRDLGTEVLSGASKGYNICLFAYGQTGSGKTYTMLGT-----------PAS 119

  Fly   131 IGIIPRALSHLF---DELRMMEVEYTMRISYLELYNEELCDLLSTDDTTK---IRIFDDSTKKGS 189
            :|:.||....||   |:...|....::::|:||:|||.:.|||...:..|   :|: .:..:.|.
  Rat   120 VGLTPRICEGLFIREDDCASMPYSRSIKVSFLEIYNERVRDLLKQSNQNKSYTLRV-REHPEMGP 183

  Fly   190 VIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIR----ENGIEGED 250
             .:|||.:..|.|...|.:|||:|...|.||.|.::..|||||.:|:|  |..    :|.:..|
  Rat   184 -YVQGLSQHAVTSYQQVLQLLEEGIANRITAATHVHEASSRSHAIFTI--HCTQATLQNNLPSE- 244

  Fly   251 MLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVD-------------- 301
              ...|:|||||||||....:..:.  |:.|..|||:||:|||.||:.|..
  Rat   245 --TASKINLVDLAGSERADPSYCKD--RITEGANINKSLVTLGIVISTLAQNSQVFSSCQSLSSA 305

  Fly   302 ------------------------RAPHVPYRESKLTRLLQESLGGRTKTSIIATISPGHKDIEE 342
                                    |..::|||:|.||.||:|||||.:||.::||:||.|....|
  Rat   306 ASSGGDSGIPSTTSGTSSGGGPARRQSYIPYRDSVLTWLLKESLGGNSKTIMVATVSPAHTSYSE 370

  Fly   343 TLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEIDKLKRDLMAARDKNGIYL---AEETYGE 404
            |:||:.||..||||.|||:||:....| :::|..|||::||..|:....:|...|   .:|:..|
  Rat   371 TMSTMRYASNAKNIINKPQVNEDANVK-LIRELREEIERLKAMLLNFELRNFSSLNDDLDESLQE 434

  Fly   405 IT----LKLESQNRELNEKMLLLKALKDEL-----QNKEKIFSEVSMSLVEKTQELKKTEENLLN 460
            :.    ||:::..:...:|....:||.:..     :|:.::..:.|:      ..|...|:::|:
  Rat   435 LVFQNDLKIDTLTQHWTQKPNNRQALMEHYGVGINRNRARVVIDSSL------PHLMALEDDVLS 493

  Fly   461 TKGTLLLTKKVLTKTKR-RYKEKKELVASHMKTEQ----VLTTQAQEILAAADLATDDTHQLHGT 520
            |...|...|:..|:..| ...:::::|......|:    :.:|....||..:..|       ..|
  Rat   494 TGIVLYHLKEGTTRIGRIDSDQEQDIVLQGQWIERDHCTITSTCGVVILRPSQGA-------RCT 551

  Fly   521 IERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKEQLSQEMVNSSYVSQRLALNS 585
            :..|     ::..||     |:.....:..|....::....|....|.||.:....|     |.|
  Rat   552 VNGR-----EVTASC-----RLTQGAVITLGKAQKFRFNHPAEAAALRQERLKVGEV-----LGS 601

  Fly   586 SKSIEML------------------KE---MCAQSLQDQTNLHNKLIGEVMKISDQHSQAFVAKL 629
            |.|:|.|                  ||   :..||.:||..|.|..|.  .:...:..|..|..|
  Rat   602 SGSLEWLDLDGDVSASRLGLCPVLRKERRVLEEQSDKDQQPLRNGKIS--YRAQTEQQQCHVEAL 664

  Fly   630 MEQMQQQQLLMSKEI---QTNL-QVIEENNQ---RHKAMLDSMQEKFATIIDSSLQSVEEHAKQM 687
            .:|.::.|..:.||:   ||:: :.|.:|.|   |.:..|.:::|           :.:|.....
  Rat   665 KQQAKEGQSRVQKELKLDQTHINRKITDNQQWLLREETWLSNLRE-----------TQQEGDCGE 718

  Fly   688 HKKLEQLGAMSLPDA----------EELQNLQEELANERALAQ---------------------- 720
            .|:||   |...|||          ..|...|:.:...|.|.:
  Rat   719 EKELE---AFVAPDAWLPTVPQTPPSPLVQSQKRVVQPRCLRKHTSRATVWNIRQKKVSFQLERI 780

  Fly   721 -QEDALLESMMMQMEQIKNL---------------------------RSKNSISMSVHLNKMEES 757
             ::..|||: ..::||:..|                           ||:.:...|:.|.::...
  Rat   781 IKKRRLLEA-QRRLEQLNALFWIQDNGTSKAPSWASSSNTTGSGSQRRSRWTTCSSLSLQRLCSQ 844

  Fly   758 RLTRNHRIDDIKSGIQDYQKLGIEASQSAQAELTSQMEAGMLCLD---QGVA-----NC-SMLQV 813
            ||::      ::|.:.::..   .|......:||.||....|..|   |..|     .| ....:
  Rat   845 RLSQ------LRSAVMNWDP---SAMSPPVPDLTQQMPEKTLSTDTVPQATACPPRTGCLGRNSL 900

  Fly   814 HMKNLNQKYEKETNENVGSVRVHHNQVEIICQESKQQLEAVQEK--------------------T 858
            |.... :|:......:|.|.::.....: .||.|.|.....::|                    .
  Rat   901 HSSRW-RKFSPARGASVSSQKIESFGKQ-SCQMSSQGQSTKKQKPTDGSRIFTPAAQTKAKGLVA 963

  Fly   859 EVNLEQMVDARQQLIT--------------EDRQRFIGHATVATDLVQESNRQFSEHAEHQRQQL 909
            .||.:.:....:...|              ...::..||..|....:.||.......|..:.|::
  Rat   964 SVNTQTVWQKEESCATYKAPKETTSHPTYLSGSEQVAGHRKVVKTSLAESKPPPPSRASKKHQRV 1028

  Fly   910 QICEQELVRFQQSELKTYAPTGTTPSKRDFVYPRTLVATSPHQEIVRRYRQELDWSDLDTTATID 974
            .......:..:.|.|....|....||..|   |.:...:.|..:.||  .::.|.||.:::.::|
  Rat  1029 LAARARDIAKKFSRLSCGCPLKKQPSAED---PTSFTDSRPIMDHVR--EEDKDLSDTESSYSVD 1088

  Fly   975 ECSEGEHDVSMHSVQELSETETIMNSTPIEPVDGVTVKRGCGTTRNSNSNALKPPVATGGKRS-- 1037
            ..|.    :.....:||.:.|.:.....:...|         .:.:.||...:..:|..|.:|
  Rat  1089 SLSY----IYAKVPKELLKPEELQGKWDLPDPD---------NSESGNSQISEDSLAGKGHQSLP 1140

  Fly  1038 ---------SSLSRSLTPSKTSPRGSPAF 1057
                     .....|......|.||.|.:
  Rat  1141 ENSAGEYSMKDYGHSRARPSASVRGLPMY 1169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	151/411 (37%)
		SMC_prok_B	<408..728	CDD:274008	75/390 (19%)
		SMC_prok_B	<651..>921	CDD:274008	60/375 (16%)
		Microtub_bind	923..>1004	CDD:464048	17/80 (21%)
Stard9	XP_017447698.1	KISc_KIF1A_KIF1B	2..391	CDD:276816	149/409 (36%)
		Kinesin_assoc	390..504	CDD:465047	27/120 (23%)
		FHA	475..592	CDD:469597	24/139 (17%)
		AtpF	<4207..>4247	CDD:440475
		SRPBCC	4378..4552	CDD:472699