Protein Alignment Klp61F and kif11

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001016116.2
• Gene: kif11 / 548870
• XenbaseID: XB-GENE-978999
• Length: 1067
• Species: Xenopus tropicalis
• Alignment Length: 1076
• Identity: 384/1076 - (35%)
• Similarity: 578/1076 - (53%)
• Gaps: 144/1076 - (13%)

  Fly     8 TSRQPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHT--LDSKLTKK-FTFDRS 69
            :|::..|  .:||||.||.||.|..||...|..|::...||:.|...|  ::.||.|| :|||..
 Frog     9 SSKKDDK--GKNIQVVVRCRPFNQLERKASSHSVLECDAPRKEVCVRTGGINDKLGKKTYTFDMV 71

  Fly    70 FGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGII 134
            |||.:||.|||..||.|:::||:.|||||||||||||||||.||.|..:|:.:.:||.|...|||
 Frog    72 FGPAAKQIDVYRSVVCPILDEVIMGYNCTVFAYGQTGTGKTFTMEGERSADEEFTWEQDPLAGII 136

  Fly   135 PRALSHLFDELRMMEVEYTMRISYLELYNEELCDLL--STDDTTKIRIFDDSTKKGSVIIQGLEE 197
            ||.|..:|::|.....|:::::|.||:|||||.|||  |.|...::::|||...|..|||:||||
 Frog   137 PRTLHQIFEKLSENGTEFSVKVSLLEIYNEELFDLLSPSPDVGERLQMFDDPRNKRGVIIKGLEE 201

  Fly   198 IPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGEDMLKIGKLNLVDL 262
            :.||:||:||.:||:|..|||||:|||||.|||||:|||:.:|::|..::||:::||||||||||
 Frog   202 VSVHNKDEVYHILERGAARRKTASTLMNAYSSRSHSVFSVTIHMKETTVDGEELVKIGKLNLVDL 266

  Fly   263 AGSENVSKAGN-EKGIRVRETVNINQSLLTLGRVITALVDRAPHVPYRESKLTRLLQESLGGRTK 326
            |||||:.::|. :|  |.||..|||||||||||||||||:||||:|||||||||:||:|||||||
 Frog   267 AGSENIGRSGAVDK--RAREAGNINQSLLTLGRVITALVERAPHIPYRESKLTRILQDSLGGRTK 329

  Fly   327 TSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEIDKLKRDLMAARD 391
            ||||||:||...::|||:||||||:|||||.|||||||||||:.::|||||||::|||||..||:
 Frog   330 TSIIATVSPASINLEETVSTLEYANRAKNIMNKPEVNQKLTKRALIKEYTEEIERLKRDLATARE 394

  Fly   392 KNGIYLAEETYGEITLKLESQNRELNEKMLLLKALKDELQNKEKIFSEVSMSLVE-------KTQ 449
            |||:||:.|.|.::..|:.||...:.|....:.|:::|::...::|:|....|.|       |.:
 Frog   395 KNGVYLSNENYEQLQGKVLSQEEIITEYTEKITAMEEEIKRINELFAENKKELEECTTILQCKEK 459

  Fly   450 ELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKKELVASHMKTEQVLTTQAQEILAAADLATDDT 514
            ||::|::||..:|..|.....|:|..:              .||:.|...|.::|......:.|.
 Frog   460 ELEETQKNLHESKEQLAQEAFVVTALE--------------TTEKKLHGTANKLLTTVRETSKDV 510

  Fly   515 HQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKE----QLSQEMVNSS 575
            ..||..::|:|.:|:...:..:.|.::|.....:|..|::.|..:|..:.:    .:...:..||
 Frog   511 SGLHAKLDRKRAVDQHNTQVHENFAEQMNKRFSVIERSVDEYSVKQQGMLDFYTNSIDDLLGASS 575

  Fly   576 YVSQRLALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVMKISDQHSQA--FVAKLM-------E 631
            ......|...:||...::|..::.:.     |:  :.|::|.....|||  .:.|||       |
 Frog   576 AALSVTATAVAKSFTSVQETVSEKVS-----HS--VDEILKQETLSSQAKDDLQKLMAAHRTGLE 633

  Fly   632 QMQQQQLL------------MSKEIQTNLQVIEENNQRHKAMLDSMQEKFATIIDSSLQSVEEHA 684
            |..:..||            :|..:| |.|.:.:....||..::|    |.|          ||:
 Frog   634 QALRTDLLPVVTAVLNLNSHLSHCLQ-NFQAVADKIDSHKEEMNS----FFT----------EHS 683

  Fly   685 KQMHK-KLEQLGAMSLPDAEELQNLQEELANERALAQQEDALLESMMMQMEQIKNL-----RSKN 743
            :.:|: :|:...|:|     .:|:..|.|..|...||.         |..|.:.||     ...|
 Frog   684 RSLHRLRLDSGSALS-----SIQSEYESLKVEIETAQS---------MHSEGVNNLIGSLQNQLN 734

  Fly   744 SISMSVHLN---------KMEESRLTRNHRIDDIKSGIQDY------------QKLGIEASQSAQ 787
            .::|....|         |:::|.......:|.|.|...::            |.:.:|..|.|.
 Frog   735 LLAMETQQNFSGFLAKGGKLQKSVGCLQQDLDSISSDAIEHTSSHHDKFAGQSQDIAVEIRQLAA 799

  Fly   788 AELTSQMEAGMLC--LDQGVANCSMLQVH-MKNLNQKYEKETNENVGSVRVHHNQVEIICQESKQ 849
            :.:.:..|:...|  |...:...|....| .::.:|:.:....|.|..:|.           ||:
 Frog   800 SNMGTLEESSKQCEKLTGSINAISRESQHWCESASQQIDSLLEEQVCYLRT-----------SKK 853

  Fly   850 QLEAVQEKTEVNLEQMVDARQQLITEDRQRFIGHATVATDLVQESNRQFSEHAEHQRQQLQICEQ 914
            .|:::|:..||.....|....:.:...||......|...:.|::......|......:|:|..:.
 Frog   854 HLQSLQKDVEVGCGASVVEITEHVNAQRQAEEKALTSLVEQVRDDKEMLGEQRLELHEQVQSGQN 918

  Fly   915 ELVRFQQSELKTYAPTGTTPSKRDFVYPRTLVATSPHQEIVRRYRQELDWSDLDTTATIDECSEG 979
            ::..:...||:...||||||.:||:|||..||.|.|...::.::||:.           .|..|.
 Frog   919 KVNSYLNEELRNDVPTGTTPQRRDYVYPSLLVRTKPRDVLLEQFRQQQ-----------QEYLES 972

  Fly   980 EHDVSMHSVQELSETETIMNSTPIEPVDGVTVKRGC 1015
            ...|...:|:...|.:::.:..|:...|.|..::.|
 Frog   973 ISSVISEAVEPPVEQDSLEDEPPVAVNDSVMSEKSC 1008

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	212/353 (60%)
		SMC_prok_B	<408..728	CDD:274008	77/352 (22%)
		SMC_prok_B	<651..>921	CDD:274008	56/299 (19%)
		Microtub_bind	923..>1004	CDD:464048	25/80 (31%)
kif11	NP_001016116.2	KISc_BimC_Eg5	16..368	CDD:276815	212/353 (60%)
		SMC_prok_B	376..>635	CDD:274008	74/279 (27%)
		sbcc	406..>915	CDD:129705	115/569 (20%)
		Microtub_bind	927..1066	CDD:464048	28/93 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1048..1067