Protein Alignment Klp61F and Klp54D

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Alignment Length: 658
• Identity: 191/658 - (29%)
• Similarity: 300/658 - (45%)
• Gaps: 114/658 - (17%)

  Fly     3 ISGGNTSRQPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTR---------HTLDS 58
            ::..:|..:.......||.|.|||||||.:|:..|....:...|..:|:..         |..||
  Fly   150 VASKSTGSEECSTPEDNINVVVRVRPLNDKEKRDRHGSTLQFPGNGQVILEGNDVGQKRSHNRDS 214

  Fly    59 KLTKKFTFDRSFGPESKQCDV--YSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAEL 121
              .:.||::..|.|.:.|.|:  || .:..:||..:.|::||.|.|||||:|||||:.|.....:
  Fly   215 --VRVFTYNVVFEPGATQEDILDYS-GIKRIIEMGIEGFSCTAFCYGQTGSGKTHTLTGPPDLFV 276

  Fly   122 KSSWEDDSDIGIIPRALSHLFDELR-MMEVEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDST 185
            ......|...|:|.|:..:||..:: ..:|.|.::.|::|:|||.:.|||:.....|......|.
  Fly   277 GKPNPKDPRHGLIFRSFLYLFQLIKNRKDVNYVLKASFMEIYNERVIDLLNPGSARKPLAVRWSK 341

  Fly   186 KKGSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHI----RENGI 246
            |.|...::.|..:.....||:..:||:|...|...:..||..||||||:  :.|||    :.:|
  Fly   342 KSGGFFVENLFTVDCEELDDLLAVLEEGMRNRAVGSHAMNDHSSRSHTI--LTVHILSDQQTDG- 403

  Fly   247 EGEDMLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVD---RAPHVPY 308
             |..:.|.||:|.|||||||...|..:| |..:.|..|||:||:.||..|::|.|   |..|:||
  Fly   404 -GVFLSKHGKINFVDLAGSELTKKTMSE-GKTLEEANNINKSLMVLGYCISSLSDSKKRTGHIPY 466

  Fly   309 RESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLK 373
            |:|:||:||.:||.|...|.:||.:||.|.:..|||:||.||.|||.|:.||.:.....:..:|
  Fly   467 RDSQLTKLLADSLAGNGVTLMIACVSPAHYNHAETLNTLRYASRAKRIRTKPVIKMDPREALIL- 530

  Fly   374 EYTEEIDKLKRDLMAARDKNGIYLAEETYGEITLKLESQ---NRELNEKMLLLK----------- 424
                   .||||:.|.:       .|..:.:..|.|..|   |....|.:|.|:
  Fly   531 -------SLKRDIHALQ-------MENDHLKAALNLHHQAAPNGGPVENLLELQLDRVSSGGGVP 581

  Fly   425 ALKDELQNKEKIFSEVSMSLVE----KTQELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKKEL 485
            ..|.:||...::.......||:    :.:.|::...:|...:.|:|..::::.:...|..:|.|.
  Fly   582 VPKVDLQRLPELDGSELAELVKLYMVENESLRQENNHLFTVRETILRDQEIVCRENERLLKKLED 646

  Fly   486 VASHMKTEQVLTTQAQEILAAADLATDDTHQLHGT------------------IERRRELDEKIR 532
            |       ..:..::..|.|...::.....:..||                  ||:|  :.|...
  Fly   647 V-------NKVCVRSPLIPARPAISPTTGKETPGTEIWTNPEPLQSPPGPDLPIEQR--MSENAN 702

  Fly   533 RSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKEQLSQEMVNS-----SYVSQRLALN-----SSK 587
            |..|..:.|:               ||:...|..|.  |.|:     |.:::.|.||     :.:
  Fly   703 RRTDTAQKRI---------------DQKRIAKNILI--MANAFRKPDSDITKELNLNPEEAHAKQ 750

  Fly   588 SIEMLKEM 595
            |.|.:.:|
  Fly   751 STEFMPDM 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	139/366 (38%)
		SMC_prok_B	<408..728	CDD:274008	43/234 (18%)
		SMC_prok_B	<651..>921	CDD:274008
		Microtub_bind	923..>1004	CDD:464048
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	139/361 (39%)