Protein Alignment Klp61F and sub

DIOPT Version :9

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001286548.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Alignment Length: 600
• Identity: 167/600 - (27%)
• Similarity: 264/600 - (44%)
• Gaps: 163/600 - (27%)

  Fly    21 QVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDS------KLTKKFTFDRSFGPESKQCDV 79
            ||::|:||:....:....:|..:|     ::|...:||      ::.|.|.|...|.....|.|:
  Fly    89 QVFLRLRPVKDASKAYIVSEEANV-----LITSCKVDSTSNNVNRMEKHFGFTSIFDSTVGQRDI 148

  Fly    80 YSVVVSPLIEEVLNGYNC-TVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIPRAL----- 138
            |...|.|.|.|    ..| |:..||.:|:|||:|::|           ||...|||||||
  Fly   149 YDTCVGPKIME----EECVTIMTYGTSGSGKTYTLLG-----------DDVRAGIIPRALENIFT 198

  Fly   139 ---------------------------------------------------------SHLFDELR 146
                                                                     .|:|:...
  Fly   199 IYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFETKA 263

  Fly   147 MMEVEYTMRISYLELYNEELCDLLSTD---------DTTKIRIFDDSTKKGSVIIQGLEEIPVHS 202
            ..:|...:.:|::|:|||.:.|||:..         ....::|..:   ||.|.|:||..:.|.|
  Fly   264 STDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGN---KGHVFIKGLTSVFVTS 325

  Fly   203 KDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSI-VVHIRENGIEGEDMLKIGKLNLVDLAGSE 266
            .::..:||..|::|...|:|.:||.|||||.||:: ::....:||..:...|     ..||||||
  Fly   326 SEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQSSYK-----FCDLAGSE 385

  Fly   267 NVSKAGNEKGIRVRETVNINQSLLTLGRVITAL-----VDRAPHVPYRESKLTRLLQESLGGRTK 326
            .|:..|. .|:|::|..|||.||:.|||.:.|.     ...|..:|||:||||.|||.:|.|:.|
  Fly   386 RVNNTGT-SGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLGKEK 449

  Fly   327 TSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYT------EEIDKLKRD 385
            .::|.|::|..|..||.|:.|.:|..||||         :.|:.|:|::.      .|..|:.
  Fly   450 LAMIVTVTPLDKYYEENLNVLNFASIAKNI---------IFKEPVIKQHRVSYCGFMEFSKMS-- 503

  Fly   386 LMAARDKNGIYLAEETYGEITLKLESQNRELNEKMLLLK---ALKDELQNKEKIFSEVSMSLVEK 447
                       ..|.  |:.|.:||.:|..|..::..||   .|:.:|. :||:..|::.:..|.
  Fly   504 -----------TCEG--GDYTKELEDENVRLQLEIEQLKYDHVLQMQLL-EEKLRRELTATYQEI 554

  Fly   448 TQELKKTEENLLNTKGTLLLTKK----VLTKTKRRYKEKKELVASHMKTE-QVLTTQAQEILAAA 507
            .|..||..|:....|  ||:.::    :|:..:|||:|:.|    .:|.| :.|...|.:    .
  Fly   555 IQNNKKQYEDECEKK--LLIAQRESEFMLSSQRRRYEEQIE----DLKDEIEELKNPASD----T 609

  Fly   508 DLATDDTHQLHGTIE 522
            |: :||.::....||
  Fly   610 DI-SDDPNESKSPIE 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	125/427 (29%)
		Kinesin	25..356	CDD:278646	121/414 (29%)
		Microtub_bind	923..>1009	CDD:290642
sub	NP_001286548.1	KISc	89..477	CDD:276812	121/416 (29%)
		Kinesin	93..479	CDD:278646	121/414 (29%)
		GBP_C	<512..603	CDD:303769	27/97 (28%)
		coiled coil	576..586	CDD:293879	1/9 (11%)
		coiled coil	592..603	CDD:293879	3/14 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437844
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840