Protein Alignment Klp61F and Klp98A

DIOPT Version :9

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_524532.2
• Gene: Klp98A / 43310
• FlyBaseID: FBgn0004387
• Length: 1265
• Species: Drosophila melanogaster
• Alignment Length: 1263
• Identity: 307/1263 - (24%)
• Similarity: 519/1263 - (41%)
• Gaps: 349/1263 - (27%)

  Fly    19 NIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDS------KLTKKFTFDRSF------G 71
            :::|.|||||.||||..:.:..::::...:..:.:..|.|      .....||||.|:      .
  Fly     3 SLKVAVRVRPFNSREIDMDAQLIMEMENKKTRLLKPRLQSIRDAGRDNHHDFTFDYSYWSFDAED 67

  Fly    72 PE-SKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIP 135
            |. :.|..|||.:.:.:::....|||..||||||||:|||.||:|.           .::.|:||
  Fly    68 PHFATQEQVYSDLGNDVVDCAYEGYNACVFAYGQTGSGKTFTMMGT-----------PNNPGLIP 121

  Fly   136 RALSHLFDELRMME---VEYTMRISYLELYNEELCDLLSTDDT---TKIRIFDDSTKKGSVIIQG 194
            |....||..:|:.:   ..|....||||:|||.:.|||:...|   .::|    ..:.....::.
  Fly   122 RICEELFARMRVGQESGTGYRTHASYLEIYNERVKDLLAAQSTGHGLRVR----EHRSLGPYVEN 182

  Fly   195 LEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSI--VVHIRENGIEGEDMLKIGKL 257
            |.:..|...|::.:.:.:|..:|.||:|.||..|||||.:|:|  |..:..|.:..|   .:.|:
  Fly   183 LSQHAVSDFDEIQECIARGNAQRTTASTNMNDTSSRSHAIFTITFVQAVFMNDMPSE---TVSKI 244

  Fly   258 NLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVD--------------------- 301
            :||||||||..:..| ..|.|::|..:||:||:|||.||:||.:
  Fly   245 HLVDLAGSERANATG-ATGQRLKEGAHINKSLVTLGSVISALAEQTGGGHNSSSSALATTPNGAS 308

  Fly   302 -RAPHVPYRESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQK 365
             |..::|||:|.||.||::||||.:||.:||.:||...:..||||||.||:|||||.|||.||:.
  Fly   309 KRVLYIPYRDSILTWLLKDSLGGNSKTIMIAALSPADCNYSETLSTLRYANRAKNIINKPTVNED 373

  Fly   366 LTKKTVLKEYTEEIDKLKRDLMAARDKNGIYLAEETYGEITLKL--ESQNRELNEKMLLLKALKD 428
             |...:::|..|||:|||.  |.|.|.:.:        :.:||:  :.|.:|..||:
  Fly   374 -TNVKLIRELREEINKLKS--MLAGDIHSL--------QPSLKVLADLQKKEAQEKV-------- 419

  Fly   429 ELQNKEKIFSEVSMSLVEKTQELKKTEENLLNTKGTLLLTKK----VLTKTKRRYKEKKELVASH 489
                           |.|:..|..|..:::|..:.:|.|.|.    ||.      .|...|:..|
  Fly   420 ---------------LTEEWTEKWKVAQSILQEQKSLGLRKSGVGVVLD------SEMPHLIGIH 463

  Fly   490 ------------MKTEQVLTTQAQEILAAADLATDDTHQLHGTIERRR---ELDEKIRRSC---- 535
                        .:.|..:.::..::....:||.|.....|.:|..:.   .|.......|
  Fly   464 NDVTTGVTLYSLKEGETRIGSEDADVAQDIELAGDGIRAQHCSIFLKGGVVTLHPWPLAQCWVNA 528

  Fly   536 ---DQFKDRMQDNLEMIGGSLNLYQDQQAALKEQLSQEMVNSSYVSQRLALNSSKSIEMLKEMCA 597
               |:.|...|.::.::|.: |:::....|...:|.:::..|.....||:|.:|....:|  .|:
  Fly   529 HLIDEPKQISQGDIILLGRT-NIFRFNNPAEAAKLRKDLSRSQLDMSRLSLITSSKENLL--TCS 590

  Fly   598 ----------------------------QSLQDQT--------NLHNKLIGEVMKISDQHSQAFV 626
                                        ..|||:.        |...:|..|.:::.||: :..|
  Fly   591 IYSDEDGASPYKRPERQYYPQRPMSRDDPELQDENRKILDTIENALKQLNVERVQMHDQY-KTKV 654

  Fly   627 AKL--------MEQMQQQQLLMSKE----IQTNLQVIEENNQR------------HKAMLDSMQE 667
            .||        .|:|...|||..:|    .:.::.:.|:||::            .:..|||.:.
  Fly   655 RKLTEELIRLEQEEMDGLQLLNCREQELIARKDMLLWEKNNEKVQIDIVCRQISAFQTQLDSKKR 719

  Fly   668 KFATIIDSSLQSVEEHAK--QMHKKLEQ------------------LGAMSLPDA-----EELQN 707
            .|:..:...||.:::..|  :|..|:|:                  ..|..:.|.     ||::.
  Fly   720 DFSEYVAKELQELQDCGKLDEMGMKIEEGTPLNDELLLQVSDSLDLFAAQFIKDTVRRNNEEIRK 784

  Fly   708 LQEELA-NERAL-------AQQEDALLESMMMQMEQIKNLRSKNSI----------SMSVHLNKM 754
            |.|::| .||.|       |:.::.:|| :..|:|:::..|:::..          :|.:.|...
  Fly   785 LDEQIAEKERILNASTTKIAKVDETMLE-IQAQLERLRLERAESEAESQAMRAKKQNMKLQLGNK 848

  Fly   755 EESRLTRNHRIDDIKSGIQDYQKLGIEASQSAQAELTSQMEAGMLCLDQ--GVANCS------ML 811
            ..|..|..:..||: |....|:.  .:...:||:.| |.:.:..:...|  .::|||      ..
  Fly   849 SMSTSTSTNEADDV-SKSDTYET--CDTFHTAQSNL-SLVSSPTITEGQQSPLSNCSCDAEDEAE 909

  Fly   812 QVHMKNLNQKYEK---------ETNENVGSVRVHHNQVEIICQESKQQLEAVQEKTEVNLEQMVD 867
            .....:|:...|:         .:....|||.:..:.....|..|.|   |:...:.|.|    |
  Fly   910 DTRKDDLSGSSEETSRTCTAGPSSGSGSGSVGIGGSGSAPSCTPSSQ---AIMSDSGVCL----D 967

  Fly   868 ARQQLITEDRQRFIGHATVATDLVQESNRQFSEHAEHQRQQLQICEQELVRFQQSEL-------K 925
            :|.|.|.:                       :.|..:.:|.::..:::.......||       :
  Fly   968 SRNQAILQ-----------------------NGHLNNYKQAVRTSDEDTGSCSSCELGRHSDVAR 1009

  Fly   926 TYAPTGTTPSKRDFVYPRTLVATS-----------PH----QEIVRRY---RQELDWS--DLDTT 970
            .|.|..:.  :|.....:.|:..:           .|    |::.|||   .||:..|  ||:..
  Fly  1010 PYCPLHSL--RRKIAAQKALIMKNLETDLNKAQLDEHIADLQDLQRRYIQMEQEMLQSVQDLEAH 1072

  Fly   971 ATIDECSEGEHDVSMHSVQELSETETIMNSTPIEPVDGVTVKRGCGTTRNSNSNALKPPVATGGK 1035
            |   :|...|.. .|....||:  .:||.|:.:.|           |:...:::.:..|
  Fly  1073 A---QCCADERS-GMERQYELA--SSIMRSSVMSP-----------TSMEESTSQIYSP------ 1114

  Fly  1036 RSSSLSRSLTPSKTSPRGS-----PAFV 1058
               |::||....:..|.|.     |:||
  Fly  1115 ---SMTRSCPSMREFPEGEHFITIPSFV 1139

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	140/388 (36%)
		Kinesin	25..356	CDD:278646	131/373 (35%)
		Microtub_bind	923..>1009	CDD:290642	26/112 (23%)
Klp98A	NP_524532.2	KISc_KIF1A_KIF1B	2..371	CDD:276816	138/386 (36%)
		KISc	3..371	CDD:214526	138/386 (36%)
		Kinesin_assoc	370..478	CDD:292801	32/147 (22%)
		FHA	456..555	CDD:238017	15/99 (15%)
		PX_KIF16B_SNX23	1131..1259	CDD:132784	3/9 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437724
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D24620at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.850