Protein Alignment Klp61F and zgc:56231

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_998353.1
• Gene: zgc:56231 / 406257
• ZFINID: ZDB-GENE-040426-1914
• Length: 810
• Species: Danio rerio
• Alignment Length: 858
• Identity: 199/858 - (23%)
• Similarity: 357/858 - (41%)
• Gaps: 246/858 - (28%)

  Fly     2 DISGGNT----SRQPQKKSNQNIQVYVRVRPL-------NSRERCI--RSAEVVDVVGPREVVTR 53
            ::||.::    |...:....|.::||::|||.       |..:.|:  ..:|.:.:..|:...:.
Zfish    30 ELSGVSSITSQSENAEIHEQQQLRVYLKVRPFSVEELKNNEDQGCVVLEDSETIVLHAPKGSASM 94

  Fly    54 HTLDSKLTK---KFTFDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVG 115
            .:.:..:.:   ||:|.:.|||...|.:.:...:|..::..|:|.|..||:||.|..|||:|:.|
Zfish    95 KSSEKGIGQQVYKFSFSQIFGPNCNQTEFFEGTISSQVQAFLHGKNALVFSYGVTNAGKTYTIQG 159

  Fly   116 NETAELKSSWEDDSDIGIIPRALSHLFDEL-----------------------RMMEVE------ 151
            :           ..|.||:||||..||..:                       .::::|
Zfish   160 S-----------PKDPGILPRALEVLFKHIGGRQYEHMDLKPYLSSDVQKLDSELVKLERNAKAA 213

  Fly   152 --------------------------------------------------YTMRISYLELYNEEL 166
                                                              |::.:::.|:|||.:
Zfish   214 LFSLLKEDPEPTKLRKRSSTSSINSLSFSNVSYDHTVDSADGMADEAHCFYSVWVAFYEIYNEHV 278

  Fly   167 CDLLSTDDTTK------IRIFDDSTKKGSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMN 225
            .|||....::|      :|:.:|||  ||..|:.|..:.|.:.::..|:|..|.:.|..|.|.||
Zfish   279 YDLLQPAQSSKTKRRAALRVCEDST--GSSYIRDLRWVNVQNTEEFSKVLRVGNKNRSAAATKMN 341

  Fly   226 AQSSRSHTVFSIVVHIRENGIEGEDMLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLL 290
            ..|||||::|:|.: ||   |||.|:..:.:|:|.||||||..:|. ...|.|::|..|||.|||
Zfish   342 QSSSRSHSIFTIKL-IR---IEGADVQALSELSLCDLAGSERCNKT-KTFGDRLKEAGNINNSLL 401

  Fly   291 TLGRVITALVDR-----APHVPYRESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYA 350
            .||:.|.||.:.     ..:||:||||||||.|....||.:.|:|..|:......:|||..::::
Zfish   402 ILGKCIAALRNNQGFRTKSYVPFRESKLTRLFQGMFCGRGRASMIVNINQCASTYDETLHVMKFS 466

  Fly   351 HRAKNIQN--KPEVNQKLTKKTVLKEYTEEIDKLKRDLMAARDKNGIYLAEETYGEITLKLESQN 413
            ..||.:..  .|...:.|..:.|      .:|  .:.|:    |||:             ::.|
Zfish   467 AVAKQVLQVIPPRSLESLAPRIV------GLD--GKPLL----KNGV-------------IDDQ- 505

  Fly   414 RELNEKMLLLKALKDELQNKEKI-FSEVSMSLVEKTQELKKTEENLLNTKGTLLLTKKVLTKTKR 477
                       |:.|.|..:|.: ..|..||::        .:|.|:|...:|        :.|.
Zfish   506 -----------AVDDYLSEEELLDGDEADMSIL--------PQEELVNLVESL--------RVKL 543

  Fly   478 RYKEKKELVASHMKTEQVLTTQAQEILAAADLATDDTHQLHGTIERRRELDEKIRRSCDQFKDRM 542
            ..:.:|.|:......:::.....|:|:.|        .:||.     |:: |.::.|   ::::|
Zfish   544 LAERRKNLLQEIQIRKEMGDAMLQQIMEA--------EELHS-----RQM-EDLKES---YEEKM 591

  Fly   543 QDNLEMIGGSLNLYQDQQAALKE---QLSQEMVNSSYVSQRLALNSSKSIEML-KEMCAQSLQDQ 603
            ....||       |::   ||||   |.:.|.:...|:.........:.:|:| |.:|  .|:.:
Zfish   592 DSTFEM-------YKE---ALKEHAYQCALERLEEDYIPIEEYKEEQERVEVLEKRVC--ELEQK 644

  Fly   604 TNLHNKLIGEVMKISDQHSQAFVAKLMEQMQQQQL-LMSKEIQTNLQVIEENNQRHKAMLDSM-- 665
            .    :..|.:..:.|...|.......|....::. |:.||               |..::::
Zfish   645 C----RCSGPLPNVQDNSMQTNALPTTEASGAERFKLLYKE---------------KCAVENLCV 690

  Fly   666 -QEKFATIIDSSLQSVEEHAKQMHKKLEQLGAMSLPDAEELQNLQEELANERALAQQEDALLESM 729
             :::|       :.|:|:...:::..|::.|...:....|:||||..|:...   |:.:.|..::
Zfish   691 EKQEF-------IMSLEQRIGELNDTLQEAGESYMEKLAEVQNLQNRLSTRE---QEIECLQSNI 745

  Fly   730 MMQMEQIKNLRSK 742
            |.:.::|..||.:
Zfish   746 MAKEKEITGLREE 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	125/451 (28%)
		SMC_prok_B	<408..728	CDD:274008	60/328 (18%)
		SMC_prok_B	<651..>921	CDD:274008	18/95 (19%)
		Microtub_bind	923..>1004	CDD:464048
zgc:56231	NP_998353.1	KISc_KIF23_like	50..470	CDD:276819	122/437 (28%)
		SMC_N	<464..>762	CDD:481474	74/406 (18%)