Protein Alignment Klp61F and Klp67A

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_523992.2
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Alignment Length: 892
• Identity: 229/892 - (25%)
• Similarity: 381/892 - (42%)
• Gaps: 242/892 - (27%)

  Fly    15 KSNQNIQVYVRVRPLNSRE-----RCI-----RSAEVVD------------VVGPREVVTRHTLD 57
            :.:.||:|.|||||.|.||     |.|     |||.:.|            ...|...:|:
  Fly     4 EQHTNIKVAVRVRPYNVRELEQKQRSIIKVMDRSALLFDPDEEDDEFFFQGAKQPYRDITK---- 64

  Fly    58 SKLTKKFT--FDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAE 120
             ::.||.|  |||.|..::...|::....:||::.|||||||:||.||.||.|||.||:|:|
  Fly    65 -RMNKKLTMEFDRVFDIDNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAGKTFTMLGSE--- 125

  Fly   121 LKSSWEDDSDIGIIPRALSHLFDELRMME--VEYTMRISYLELYNEELCDLLSTDDTTKIRIFDD 183
                    :..|:....:..|||:::...  .::.:.:||||:|||.:.:||:.....|:|  :|
  Fly   126 --------AHPGLTYLTMQDLFDKIQAQSDVRKFDVGVSYLEVYNEHVMNLLTKSGPLKLR--ED 180

  Fly   184 STKKGSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEG 248
            :   ..|::.||...|::|.:::.::|..|...|....|..||:|||||.:|.:.:.|.|   ..
  Fly   181 N---NGVVVSGLCLTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHIRITE---RK 239

  Fly   249 EDMLKIGKLNLVDLAGSENVSKAGNEKGIRVR--ETVNINQSLLTLGRVITALVDRAPHVPYRES 311
            .|..:..||:::||||||   :|.:.|||.||  |..:||:|||.||..|..|.|...|:|||:|
  Fly   240 TDTKRTVKLSMIDLAGSE---RAASTKGIGVRFKEGASINKSLLALGNCINKLADGLKHIPYRDS 301

  Fly   312 KLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKE-- 374
            .|||:|::||||..:|.::|.:|......|:|.:||:||.|||.|:.       ..|:.|||.
  Fly   302 NLTRILKDSLGGNCRTLMVANVSMSSLTYEDTYNTLKYASRAKKIRT-------TLKQNVLKSKM 359

  Fly   375 ----YTEEIDKLKRDLMAARDKNGIYLAEET---------YGEITLK--------LESQNRELNE 418
                |.::||::..:....:::|....|:.|         :..:.||        :.:..|:|.|
  Fly   360 PTEFYVKKIDEVVAENERLKERNKALEAKATQLERAGNSGFDPLELKTWYSKIDAVYAAARQLQE 424

  Fly   419 KMLLLKALKDELQNKEKIFSEVSMSLVEKTQELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKK 483
            .:|   .::.:::|            :...|.|||..|..          :|::...:|..:|..
  Fly   425 HVL---GMRSKIKN------------INYRQTLKKELEEF----------RKLMCVDQRVCQEDF 464

  Fly   484 ELVASHMKTEQVLTTQAQEILAAADLATDDTHQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEM 548
            ...|::|.|   ||:|.                            ||.:.....:..:|:
  Fly   465 RRFANYMST---LTSQM----------------------------EKYKEELPSWLSKME----- 493

  Fly   549 IGGSLNLYQDQQAALKEQLSQEMVNSSYVSQRLALNSSKSIEML-KEMCAQSLQDQTNLHNKLIG 612
                 ..|||.::..:|                 :|.||:.::| ..:..:.|:.|....|
  Fly   494 -----IAYQDLESLKRE-----------------VNKSKAYQILIVYVKYKDLELQLTKQN---- 532

  Fly   613 EVMKISDQHSQAFVAKLMEQMQQQQLLMSKEIQTNLQVIEENNQRHKAMLD--SMQEKFATIIDS 675
                |.:.|..|...:|:|.:.    ||.|..:|..:|:   ||.:..:.|  .:..:...:.:.
  Fly   533 ----IFNNHVNAINQELVENLD----LMRKSFRTACEVL---NQTYDRLEDGQKLTPEIEAVFER 586

  Fly   676 SLQSVEEHAKQMHKKLEQLGAMSLPDAEELQNLQEE----------LANERALAQQEDALLESMM 730
            .|:.:.....:.:.|:.::..:::|.|......:||          ...:|..||.:|.|..||
  Fly   587 LLRKMRFADSEANTKMAEMNPLAVPVALRSSAQEEEEPTCSLTASAKKRQRQAAQSDDDLHLSM- 650

  Fly   731 MQMEQIKNLRSKNSISMSVHLNKMEESRLTRNHRIDDIKSGIQDYQKLG---------IEASQSA 786
                  ::..|:::.|.|..|           ||.......:.:.|.||         ..:|.||
  Fly   651 ------EDFDSQDTESDSEEL-----------HRTFKRPRNLNETQVLGPCSSSSSSSTSSSSSA 698

  Fly   787 QAELTS---------QMEAGMLCLDQGVANCSMLQVHMKNLNQKYEK 824
            :..||:         |.....|..||.|          :..|:|.:|
  Fly   699 RKALTATVTKPRTVQQRLVSDLISDQNV----------RGGNEKIKK 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	136/375 (36%)
		SMC_prok_B	<408..728	CDD:274008	58/340 (17%)
		SMC_prok_B	<651..>921	CDD:274008	38/204 (19%)
		Microtub_bind	923..>1004	CDD:464048
Klp67A	NP_523992.2	KISc_KIP3_like	8..346	CDD:276821	135/364 (37%)