Protein Alignment Klp61F and pav

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_477025.1
• Gene: pav / 38515
• FlyBaseID: FBgn0011692
• Length: 887
• Species: Drosophila melanogaster
• Alignment Length: 978
• Identity: 217/978 - (22%)
• Similarity: 382/978 - (39%)
• Gaps: 308/978 - (31%)

  Fly    10 RQPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVD----VVGPREVVTRHTL---DSKLTKKFTFD 67
            |....|:...:.|:.|||||.| :..:.|..|.:    .:.|::.:.:|..   .::...::.|.
  Fly    27 RDTSDKARDPVNVFCRVRPLQS-DADLTSLRVKNSTTIALNPQDQLLQHHKPHNGAQREVQYIFK 90

  Fly    68 RSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIG 132
            ..|.|::.|.|||:.|..||:|.:|.|.|..:|.||.||:|||:||.||    |:..       |
  Fly    91 HVFQPDATQQDVYAAVAQPLVENLLKGRNSLLFTYGVTGSGKTYTMTGN----LRHR-------G 144

  Fly   133 IIPRALSHLF---------------DELRMMEV-------------------------------- 150
            |:||.|..||               |:|...|:
  Fly   145 IMPRCLDVLFRTISDYQAKKFVFKPDKLNGFEILSEEDALLERQHEMNQRFAGSGRFAFRHKDSD 209

  Fly   151 ---------------------EYTMRISYLELYNEELCDLL---STDDTTKIRIFDDSTKKGSVI 191
                                 .|::.::|:|:||..:.|||   ....|.:.:|..:...: .:.
  Fly   210 PEIASQASVEPIPLLGLDEDNMYSVFVTYIEIYNNSVYDLLEDSGIQKTLQSKIIREDANR-HMF 273

  Fly   192 IQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGEDMLK--- 253
            :.|:.|:.|.:.:|..::.:.|::|::...|::||:|||||:||:|.:.......:||::::
  Fly   274 VHGVTEVEVKTVEDALEVFQMGQKRKRMGHTVLNAESSRSHSVFNIRLVQAPTDSQGENVVQDRQ 338

  Fly   254 ---IGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDR--------AP-HV 306
               :.:|:||||||||..|:..| .|:|:||..|||.||:||...:..|.:.        || .|
  Fly   339 NITVSQLSLVDLAGSERSSRTKN-TGVRLREAGNINNSLMTLRTCLEYLRENQLAASNGLAPKKV 402

  Fly   307 PYRESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTV 371
            |||:||:|.:.:....|..:.|:|..|:|..:|.:|.:..:::|...:.:|        :.:.|
  Fly   403 PYRDSKITHMFKNYFDGEGQVSMIVCINPRIEDYDENMQVMKFAEMTQEVQ--------IARAT- 458

  Fly   372 LKEYTEEIDKLKRDL---MAARDKNGIYLAEETYGEITLKLESQNRELNEKMLLLKALKDELQNK 433
                     .:|:||   ...|..|.::           |:...|  |||  |.:...||
  Fly   459 ---------PMKQDLGLTPGRRKANKLF-----------KIAVNN--LNE--LGIPEAKD----- 494

  Fly   434 EKIFSEVSMSLVEKTQELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKKELVASHMKTEQVLTT 498
                .||.:.||                                 |....:..|..|.:.:. ..
  Fly   495 ----LEVDVGLV---------------------------------YSLGPDFPAYEMDSPEA-QI 521

  Fly   499 QAQEILAAADLATDDTHQLHGTIERRRELDEKIRRSCDQFKDRM----QDNLEMIGGSLNLYQDQ 559
            :.:|::          |.|...||:|::|...:...||.|:..:    :|||::        :.:
  Fly   522 KIRELM----------HYLEQRIEKRKKLRANLDIKCDSFRQMLMNLDRDNLQL--------RTE 568

  Fly   560 QAALKEQLSQEMVNSSYVSQRLALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVMKISDQHSQA 624
            .|:||....||...|:.:.:::.::.| ||::              |:|.|..:..:|.:
  Fly   569 LASLKAVYKQERDRSAALEKKVRIHES-SIDV--------------LNNTLSKQERQIEE----- 613

  Fly   625 FVAKLMEQMQQQQLLMSKEIQTNLQVIEENNQRHKAMLDSMQEKFATIIDSSLQSVEEHAKQMHK 689
            ...||.|   ::.:|..||       .|:..|:.|     ...|.|...|.:.:..|...::...
  Fly   614 LTFKLNE---KENMLTQKE-------HEKEKQKKK-----FSSKLAVESDKNKREFELKLREQRV 663

  Fly   690 KLEQLGAMSLPDAEELQNLQEELANERALAQQEDALLESMMMQMEQIKNL-RSKNSISMSVHLNK 753
            ||:                      ||...:.|...|.|.::|.|.:.:| ||::|.::   ||:
  Fly   664 KLQ----------------------ERMRIKDEKLRLVSNILQSEDLPSLPRSQSSENI---LNE 703

  Fly   754 MEESRLTRNHRIDDIKSGIQDYQKLGIEASQSAQAELTSQMEAGMLCLDQGVAN----CSMLQVH 814
            .:....|.......:.:...|........:.:|.........||...|:...||    .:::|.:
  Fly   704 KDRGAYTARTEESSVPATRTDIYATPRHGAAAANNRHRRSRSAGDKWLEHRAANPVPLGTIMQPY 768

  Fly   815 MKNLNQ----------------KY-----EKETNENV--------------GSVRVHHNQVEIIC 844
            :||...                ||     :.:|:.:|              |..:|..|.||.:.
  Fly   769 LKNRKSVTKLTDLKELTAHGTTKYCLVSQDADTDGDVETKLYKGNVIPTCGGGAQVVFNDVECLK 833

  Fly   845 QES 847
            |:|
  Fly   834 QKS 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	118/440 (27%)
		SMC_prok_B	<408..728	CDD:274008	60/323 (19%)
		SMC_prok_B	<651..>921	CDD:274008	44/237 (19%)
		Microtub_bind	923..>1004	CDD:464048
pav	NP_477025.1	KISc_KIF23_like	35..450	CDD:276819	117/428 (27%)
		PRK03918	<522..>687	CDD:235175	47/239 (20%)
		MKLP1_Arf_bdg	734..840	CDD:465166	20/103 (19%)