Protein Alignment Klp61F and Klp59D

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Alignment Length: 557
• Identity: 162/557 - (29%)
• Similarity: 262/557 - (47%)
• Gaps: 103/557 - (18%)

  Fly     1 MDISGGNTSRQPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSK--LTK- 62
            :|.:||..         |.|.|.||.||::.:|...::.:::.|.....::. |.|..|  |||
  Fly   224 LDPNGGTV---------QQITVCVRKRPMSRKEENSKNLDIITVPSADSLIV-HELRLKVDLTKF 278

  Fly    63 ----KFTFDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKS 123
                ||.||.:|..|.....||.....|||..:..|.|.|.|||||||:||||||.|....:::
  Fly   279 LEHHKFRFDYTFDEECSNALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFGKVQ- 342

  Fly   124 SWEDDSDIGIIPRALSHLFDEL-----RMMEVEYTMRISYLELYNEELCDLLSTDDTTKIRIFDD 183
                |...||...|...:|:|:     |.|..:.|  .|:.|:|..::.||| ..:...:|:.:|
  Fly   343 ----DCGTGIYAMAARDVFEEVSRPEYRQMGAKIT--CSFFEIYGTKVFDLL-LPNKPMLRVLED 400

  Fly   184 STKKGSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEG 248
            :.::  |::.||.|:||...:||.:|:|.|.:.|.:..|..||:|||||.||.|.:|..::.  |
  Fly   401 ARQQ--VVVVGLTEMPVTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIALHFPDSW--G 461

  Fly   249 EDMLKIGKLNLVDLAGSE-NVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDRAPHVPYRESK 312
            ..    ||.:.|||||:| .......::..|: |...||:|||.|...|.||..::.|:|:|.||
  Fly   462 PH----GKCSFVDLAGNERGADTQSADRQTRI-EGAEINKSLLALKECIRALSRQSSHLPFRGSK 521

  Fly   313 LTRLLQESL--GGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNI---------------QNKP 360
            ||::|::|.  |.:.||.:||.|||....:|.||:||.||.|.|.:               :..|
  Fly   522 LTQVLRDSFVGGKKNKTCMIAMISPSMSCVENTLNTLRYADRVKELIAKEDEHLQSVEGDGEKSP 586

  Fly   361 EVNQKLTKKTVLKEYTEEIDKLKRDLMAARDKNGIYLAEE---TYGEITLKLESQNRELN----- 417
            ::|::...:.:.   .||.|:...|    .|...:.::.|   :|..::..: |.|..||
  Fly   587 DLNEESEPEMMA---DEEGDEEPED----EDNQHLTISSEEASSYNNMSYDM-SFNHTLNILGPS 643

  Fly   418 ----------EKMLLLKALKDELQNKEKIFSEVSMSLVEKTQELKKTEENLLNTKGTLLLTKKVL 472
                      :..||::.|:....|..::          ||.  |:.|:...|::..|:....::
  Fly   644 RNVDIQEVAEQHALLVENLETYAHNFRQL----------KTD--KEIEQYTQNSESALMKLLAMV 696

  Fly   473 TKTKRRYKEKKELVASHMKTEQVLTTQAQEILAAADL 509
            .:|:.        |..:..|:::|..:.|......:|
  Fly   697 NRTRD--------VTHNYNTQKLLKEENQNAYKKGEL 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	132/377 (35%)
		SMC_prok_B	<408..728	CDD:274008	20/117 (17%)
		SMC_prok_B	<651..>921	CDD:274008
		Microtub_bind	923..>1004	CDD:464048
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	128/349 (37%)