DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klp61F and Klp59C

DIOPT Version :10

Sequence 1:NP_476818.1 Gene:Klp61F / 38135 FlyBaseID:FBgn0004378 Length:1066 Species:Drosophila melanogaster
Sequence 2:NP_611759.1 Gene:Klp59C / 37671 FlyBaseID:FBgn0034824 Length:626 Species:Drosophila melanogaster


Alignment Length:470 Identity:144/470 - (30%)
Similarity:226/470 - (48%) Gaps:72/470 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 ISGGNTSRQPQKKSNQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSKLTKK---- 63
            :..|.|:   ::.:...|.|.||.|||..:|...|..:||      .:.::|||.....:|    
  Fly   174 VRSGTTN---ERINCHQIMVCVRKRPLRRKELADREQDVV------SIPSKHTLVVHEPRKHVNL 229

  Fly    64 --------FTFDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAE 120
                    |.||..|..|.....||.....|||:.:.:|...|.|||||||:|||:||.|.....
  Fly   230 VKFLENHSFRFDYVFDEECSNATVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGR 294

  Fly   121 LKSSWEDDSDIGIIPRALSHLFDELRMM---EVEYTMRISYLELYNEELCDLLSTDDTTKIRIFD 182
            .:||.:     ||...|...:|..|:.:   ::...:..|:.|:|...:.||| .....::|:.:
  Fly   295 HQSSMD-----GIYAMAAKDVFSTLKTVPYNKLNLKVYCSFFEIYGTRVFDLL-MPGKPQLRVLE 353

  Fly   183 DSTKKGSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIE 247
            |..::..|:  ||.:.||.:..:|..|||.|...|.:..|..|::|||||.||.||:    ....
  Fly   354 DRNQQVQVV--GLTQNPVQNTAEVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVL----RSAA 412

  Fly   248 GEDMLKIGKLNLVDLAGSE-NVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDRAPHVPYRES 311
            ||.:  .||.:|:||||:| ....:..::..|: |...||:|||.|...|.||..::.|:|:|.|
  Fly   413 GEKL--HGKFSLIDLAGNERGADNSSADRQTRL-EGSEINKSLLVLKECIRALGRQSSHLPFRGS 474

  Fly   312 KLTRLLQES-LGG-RTKTSIIATISPGHKDIEETLSTLEYAHRAKNI-------QNKPEVNQKLT 367
            |||::|::| :|| :.||.:||.|||....:|.||:||.||.|.|.:       :..|:.|...|
  Fly   475 KLTQVLRDSFIGGKKVKTCMIAMISPCLHSVEHTLNTLRYADRVKELSVESIPSKRMPDANLGST 539

  Fly   368 KKT--VLKEYTEEI-------------DKLKRDLMAARDKNGIY--LAEETY----GEITLKLES 411
            ..:  |.:..|:.:             ::.::....|.|.|...  .::.||    .::..:..|
  Fly   540 SMSDIVCQSSTQRLFPCASSTSMPGGGNQAQQHTNTANDLNRSQKPTSKPTYPTSGQQLVQRKGS 604

  Fly   412 QNRELNEKMLLLKAL 426
            ..||.:  |:|.|:|
  Fly   605 SQREAS--MMLTKSL 617

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klp61FNP_476818.1 KISc_BimC_Eg5 17..365 CDD:276815 127/372 (34%)
SMC_prok_B <408..728 CDD:274008 7/19 (37%)
SMC_prok_B <651..>921 CDD:274008
Microtub_bind 923..>1004 CDD:464048
Klp59CNP_611759.1 KISc_KIF2_like 187..519 CDD:276818 124/352 (35%)
Blue background indicates that the domain is not in the aligned region.

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