Protein Alignment Klp61F and Klp31E

DIOPT Version :9

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001162935.1
• Gene: Klp31E / 34422
• FlyBaseID: FBgn0032243
• Length: 1048
• Species: Drosophila melanogaster
• Alignment Length: 1113
• Identity: 286/1113 - (25%)
• Similarity: 511/1113 - (45%)
• Gaps: 264/1113 - (23%)

  Fly    17 NQNIQVYVRVRPLNSRERCIRSAEVVDVVGPREVVTRHTLDSK-----LTKKFTFDRSFGPESKQ 76
            :.:::|.||:||.|||       |::|:.   .:.|..||...     ..|.||||..|...|.|
  Fly    11 DSSVRVAVRIRPQNSR-------ELIDMC---RICTTVTLGEPQIFLGSDKAFTFDYVFDTNSNQ 65

  Fly    77 CDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIPRALSHL 141
            ||:||..|..|::..|:|||.||.||||||:|||:||......|.:||  |...:||||||:.|:
  Fly    66 CDIYSDCVEKLVDSTLHGYNATVLAYGQTGSGKTYTMGTGFDHESESS--DSVQLGIIPRAVRHI 128

  Fly   142 FDELRMME-------------VEYTMRISYLELYNEELCDLLST-DDTTKIRIFDDSTKKGSVII 192
            |..:..:|             .::::.:.|:|||||::.|||.. :..:..:|.:|::  |.:.|
  Fly   129 FSGIEQLEGSSTSEHPAAGGSPQFSLAVQYIELYNEDIFDLLDPFNKNSNFKIHEDAS--GQITI 191

  Fly   193 QGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVV----------HIRENGIE 247
            .|....|::...|..|.|::|...|.||:|.||.||||||.:|:|.|          ::.:|.:|
  Fly   192 SGASIKPIYQPHDALKYLQQGALARTTASTKMNDQSSRSHALFTIFVRRQRLLTPSDNVPDNDLE 256

  Fly   248 GEDMLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVD---RAPHVPYR 309
                ....|.:.|||||||.: |.....|.|.||.::||..||.||..|:||.|   ||.|||||
  Fly   257 ----TLTSKFHFVDLAGSERL-KRTQATGERAREGISINCGLLALGNCISALGDKSKRALHVPYR 316

  Fly   310 ESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKE 374
            :||||||||:||||.::|.:||.:||..:|..|||:||:||:||:||:||.::||..:.:|
  Fly   317 DSKLTRLLQDSLGGNSQTLMIACVSPSDRDFMETLNTLKYANRARNIKNKVKINQDQSSRT---- 377

  Fly   375 YTEEIDKLKRDLMAARDKNGIYLAEETYGEITLKLESQ---NRELNEKMLLLKALKDELQNKEKI 436
                |.:|:|::.|.:    :.|.|...|::.:..|..   :...||..|||..:| .||.:.|.
  Fly   378 ----ISQLRREIAALQ----LELLEYKQGKLIVDCEGNTTISDTFNENKLLLSEIK-RLQQRLKS 433

  Fly   437 FSEVSMSLVEKTQELK-------------------------------------KTEEN--LLNTK 462
            ......:|.::..:||                                     ::||:  .:..|
  Fly   434 LQSTIATLTQRNADLKTNLDLNKWTSDDNSDVEIAKVVGQYMLEIEELQTKLIESEEHRKQMEIK 498

  Fly   463 GTL-------LLTKKVLTKTKRRYKEKKELVASHMK---TEQVLTTQAQEILAA---ADLATDDT 514
            .|.       :....::||.|:..:.::||:.|...   ..|.::::..|:.::   |:....|.
  Fly   499 ATTSPRNAKPVYDSDIITKAKKDLERERELLMSRSLPGIQNQNVSSEETEVASSDSEAEEVVKDL 563

  Fly   515 HQLHGTIERRRELDEKIRRS---CDQFKDRMQDNLEMIGGSL-NLYQDQQAAL-----------K 564
            ..:...||.|.:|.|::..:   .:|.:...::.|.::...: |..:::...|           |
  Fly   564 EAIDNDIEMRTKLIEQLELTNSRYEQMRTHYEEKLSVLYCKIENTQKERDDVLANMTTSVSTPSK 628

  Fly   565 EQLSQEMVNSSYVSQ--------RLALNSS----KSIEMLK--EMCAQSLQDQTN----LHNKLI 611
            :.|.:  |.:.|.|:        |...|:.    :|.:.||  |:...:|:::.|    ...||:
  Fly   629 DSLKK--VKTDYESKISHMQTEIRKLQNAQREHIRSKQQLKSHEVRIGTLRNELNELKFAKVKLM 691

  Fly   612 GEVMKISDQHSQ------AFVAKLMEQMQQQQ---LLMSKEIQTNLQVIE--------------- 652
            .::.:.|::|.|      ..:|:|:::.::|:   |.:..::....|:::
  Fly   692 KKMSQQSNRHKQEESRKSKEIAQLLKEQRRQKNAVLTLEAKVSAKEQILKRKTEEVIALRKSQRG 756

  Fly   653 ENNQRHKAMLDSMQEKFATIIDSSLQSVEEHAKQMHKKLEQLGAMSLPDAEELQNLQEELANERA 717
            ::.||..|.|.|   |.||:...|.:|.....:.:::.:    ..:..:.:.:..|::||  ||.
  Fly   757 KSGQRAPAHLTS---KIATLDGFSTRSARHRWENLYRNI----LHAARNRQLITQLEKEL--ERL 812

  Fly   718 LAQQEDALLESMMM-----------QMEQIKNLRSKNSIS-MSVHLNKMEESRLTRNHRIDDIKS 770
            :.::||...|..:|           :..::.||  |.:|| :..::..::::.:......|.::|
  Fly   813 ILEREDLSRELNIMENGQTADRQTDEFNEVDNL--KTNISYIQENIEHVQQAIMEFEDTKDTVQS 875

  Fly   771 GIQDYQKLGIEASQSAQAELTSQMEAG----MLCLDQGVANCSMLQVHMKNLNQKYEKETNENVG 831
            .:...|.|..|.|..|:|:...|..:.    |.|      |.::.:.|::      |||
  Fly   876 HVNKIQSLLDEVSTVAEAKFILQKFSDTAIVMSC------NLAIAESHLQ------EKE------ 922

  Fly   832 SVRVHHNQVEIICQESKQQLEAVQ----EKTEVNLEQMVDA--------RQQLITEDRQRFIGHA 884
                  :.::.:.|||..|.:.:|    :.:.|::..:.|:        ...:....::..|.:|
  Fly   923 ------SLLKEVKQESGIQQQILQHFLSQNSNVHIADIFDSLNLKGSNIASSVNPGSQKSLISNA 981

  Fly   885 TVATDLVQ-ESNRQFSEHAEHQRQQLQICEQELVRFQQSELKTYAPTGTT-PSKRDFVYPRTLVA 947
            |.  |:.| :.|.:|     ||           |..:::..::.:|.|.: |..:.   |:....
  Fly   982 TY--DIPQDDKNSEF-----HQ-----------VEMRRTTSRSPSPLGNSDPFDKS---PKVRRR 1025

  Fly   948 TSPHQEIV 955
            |:..|:::
  Fly  1026 TAKRQDLL 1033

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	155/379 (41%)
		Kinesin	25..356	CDD:278646	148/362 (41%)
		Microtub_bind	923..>1009	CDD:290642	6/34 (18%)
Klp31E	NP_001162935.1	KISc_KIF4	12..364	CDD:276823	151/370 (41%)
		KISc	13..370	CDD:214526	154/375 (41%)
		KASH_CCD	409..589	CDD:291334	31/180 (17%)
		RasGAP	<685..750	CDD:295371	10/64 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437893
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840