Protein Alignment Klp61F and CG5004

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_573195.1
• Gene: CG5004 / 32698
• FlyBaseID: FBgn0260748
• Length: 1247
• Species: Drosophila melanogaster
• Alignment Length: 850
• Identity: 163/850 - (19%)
• Similarity: 311/850 - (36%)
• Gaps: 269/850 - (31%)

  Fly   336 GHKDIEETLS-TLEYAHRAKNIQNKPEVN--QKLTKKTVLKEYTEEIDKLKRDLMAARDKN---- 393
            |..::|:.|. ..|||.|..::.:...|:  ..:|...:::      :::|.:....||||
  Fly   298 GGAELEDMLKICTEYADRNNSMPSTHNVSSTSSITSSPIVQ------NRIKTNGSLPRDKNKSPF 356

  Fly   394 ----------GIYLAEETYGEITLKLESQNR-ELNEKMLLLKALKDELQNKEKIFSEVSMSLVEK 447
                      .|.|...:.|...::|...|| |:|.::.:..:..|...:     |.||.:.:..
  Fly   357 PQQAGVASSANISLLSSSSGYENVRLLGPNRVEINGQIHVPASAGDGGSS-----SGVSSNALAP 416

  Fly   448 TQELKKTEENLLN----TKGTLLLTKKVLTKTKRRYKEKKELVASHMKTEQVLTTQAQEILAAAD 508
            |..::.:.|||..    |.|...:.:...||.:......|:.|:  ......|......:.::|.
  Fly   417 TAAVRASHENLNQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVS--FGNAFALAISPPPLASSAV 479

  Fly   509 LATD------------------------DTHQLHGTIERR-RELDEKI--RRSCDQFKDRMQDNL 546
            ::|.                        |..||..:.||: ::||..:  :|| ::..:.:..||
  Fly   480 VSTSKPIPIPSMVKPPLAPKPPAPNQQRDYEQLFKSFERKQQQLDRMVPAKRS-NKNINNLTLNL 543

  Fly   547 EMIGG----------------SLNLYQDQQAAL---KEQLSQEMVN---SSYV--------SQRL 581
            :.:..                |::|.|.|:..|   ::||.:|:..   |:.:        .|.|
  Fly   544 QSVESQTQSPKPSRKPAPAPRSIHLEQRQRRELIQRRKQLKRELAELPPSAGIEGLELKLGEQPL 608

  Fly   582 ALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVMKISDQHSQAFVAKLMEQMQQQQLLMSKEIQT 646
            |.::|..:::      |:||::          |.::..|.:   ..::||:.||.:|..|.||:
  Fly   609 APSASPRLQL------QALQNR----------VCRLEAQRN---ATRVMEENQQAKLKQSIEIK- 653

  Fly   647 NLQVIEENNQRHKAMLDSMQEKFATIIDSSLQSVEEHAKQMHKKLEQLGAMSLPDAEELQNLQEE 711
                 ::..::.:|||  .|:.....:...||.|.|..:...|..|.|         |.|..:||
  Fly   654 -----QDQLKKLRAML--KQKPNNACLKEELQLVCESLESDRKTFEDL---------EFQYFEEE 702

  Fly   712 LANERALAQQEDALLESMMMQMEQIKNLRSKNSISMSVHLNKMEE---SRLTRNHRIDDIKSGIQ 773
              :|...:.:|....|..:|...::..||        :.:...||   |..:......::.:|:.
  Fly   703 --SEHHASHEEFKRQEQRLMLEAELAALR--------IQIGPDEEEPGSPTSPGSTGSNLVNGVM 757

  Fly   774 DYQKLGIEASQSAQAELTSQMEAGMLCLDQGVANCSMLQVHMKNLNQK--YEKETNENVGSVRVH 836
            .....|               .|.:||              .|..||:  ..|..|||:    .:
  Fly   758 SQSLFG---------------SAELLC--------------PKRRNQEDLMSKSVNENM----FY 789

  Fly   837 HNQVEI-------------------ICQESKQQLEAVQEKTEVN-LEQMVDARQQLITEDRQRFI 881
            ::::|.                   .|::....|....::.||| ||:.|.::..:   ||...:
  Fly   790 NHKIEANTSTPKRLPLQLFEDLAGGSCEQISFNLSLQGDRFEVNPLERRVPSQDDI---DRSCKV 851

  Fly   882 ----------GHATVATDLVQESNR--------QFSEHAEHQRQQLQICEQELVRFQQSELKTYA 928
                      |.:|...|.:.|..|        |..:..||:||::    .:|.:....|.:|
  Fly   852 ANDAPISASQGASTKIFDSIMEIERNRKLLLAQQGHQVIEHERQKM----YDLKKKSHDEART-- 910

  Fly   929 PTGTTPSKRDFVYPRTLVATSPHQEIVRRYRQELDWSDLDTTATIDECSEGEHDVSMHSVQELSE 993
                          :.|::|   |:.:.:.||            ::..:.|..|..:....||.:
  Fly   911 --------------QYLLST---QQSMEQQRQ------------LESDANGGKDAKLFEKTELQK 946

  Fly   994 TETIMNSTPIEPVDGVTVKRGCGTTRNSNSNALKPPVATGGKRSSSLSRSLTPSKTSPRG-SPAF 1057
                :|..|.||||. .|::..|...|:..|          ::|:..|.:.|.:.|:..| :|..
  Fly   947 ----LNQKPGEPVDD-QVQKIAGDKENNVQN----------RKSTGSSPTTTTTTTTGGGTTPQQ 996

  Fly  1058 VRHNK 1062
            .||::
  Fly   997 QRHSQ 1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	8/31 (26%)
		SMC_prok_B	<408..728	CDD:274008	76/381 (20%)
		SMC_prok_B	<651..>921	CDD:274008	58/312 (19%)
		Microtub_bind	923..>1004	CDD:464048	13/80 (16%)
CG5004	NP_573195.1	FHA_PHLB1	1..122	CDD:438765
		SMC_N	<570..730	CDD:481474	45/205 (22%)
		Caldesmon	<664..801	CDD:460421	35/190 (18%)
		PH-like	1142..1242	CDD:473070