Protein Alignment Klp61F and Klp3A

DIOPT Version :9

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001284830.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Alignment Length: 1194
• Identity: 304/1194 - (25%)
• Similarity: 510/1194 - (42%)
• Gaps: 295/1194 - (24%)

  Fly    20 IQVYVRVRPL--NSRERCIRSAEVVDVVG-PREVVTRHTLDSKLTKKFTFDRSFGPESKQCDVYS 81
            :.|.:|||||  :..:|..|.|......| |:..|.|:       :.:|::..|..:..|.|::.
  Fly     9 VAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRN-------ESYTYNYVFDIDDSQKDLFE 66

  Fly    82 VVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIPRALSHLFDELR 146
            ..|...::::|||||.|:.||||||:|||:||.......|      |..:|:||||:..:|..:.
  Fly    67 TCVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVL------DDHVGVIPRAVHDIFTAIA 125

  Fly   147 MMEVEYTMRI--SYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVIIQGLEEIPVHSKDDVYKL 209
            .|:.|:...:  |::|||.|:..||.|:....|..: |....|..:|:.||.|:.|.|...|...
  Fly   126 EMQSEFRFAVTCSFVELYQEQFYDLFSSKTRDKATV-DIREVKNRIIMPGLTELVVTSAQQVTDH 189

  Fly   210 LEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGEDMLKIGKLNLVDLAGSENVSKAGNE 274
            |.:|...|..|.|.||..|||||.:|::.:...:  ::|:..:...:.|||||||||..||. ..
  Fly   190 LIRGSAGRAVAATAMNETSSRSHAIFTLTLVATK--LDGKQSVTTSRFNLVDLAGSERCSKT-LA 251

  Fly   275 KGIRVRETVNINQSLLTLGRVITAL--VDRAPHVPYRESKLTRLLQESLGGRTKTSIIATISPGH 337
            .|.|.:|.||||:.||.||.||.||  ...|.::|||:||||||||:||||.:.|.:||.:||..
  Fly   252 SGDRFKEGVNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPAD 316

  Fly   338 KDIEETLSTLEYAHRAKNIQNKPEVN--QKLTKKTVLKEYTEEIDKLKRDLMA------------ 388
            .::.||||||.||.||..|:|||.||  ....:..:||:.   |.||:.:|::
  Fly   317 YNVAETLSTLRYADRALQIKNKPVVNLDPHAAEVNMLKDV---IQKLRVELLSGGKMSSSLISAV 378

  Fly   389 -ARDKNGIYLAEETYGEIT-------LK-----LESQNRELNEKM--LLLKALKDEL------QN 432
             |.....|...|...|.:.       ||     |:.:||:|.:::  .||...:.|:      |.
  Fly   379 GAAGLGAIPCEESLAGSMANAAEIQRLKEQVRTLQDRNRKLQQELHQSLLDLTEKEMRAHIAEQA 443

  Fly   433 KEKIFSEVSMSLVEKTQELKKTEENLLNTKGT------LLLTKKVLTKTKRRYK-------EKKE 484
            .:|:.|.|| .|..|..:.::.:....||.|.      .||..:|..:.:|..:       |.::
  Fly   444 HDKLRSHVS-ELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHVELQRTQEELESQGHESRQ 507

  Fly   485 LVASHMKTE----------QVLTTQAQEILAAADLATDDTHQLHGTIERRRELDEKIRRSCDQFK 539
            .::|...||          ::|.:.::|..........:...::..::.::||.|:|.|:..:..
  Fly   508 RLSSRSHTEGGESGGDEVHEMLHSHSEEYTNKQMNFAGELRNINRQLDLKQELHERIMRNFSRLD 572

  Fly   540 DRMQD-NLEMIGGSLNLYQDQQAALKEQLSQEMVNSSYVSQRLALNSSKSIEMLKEMCAQSLQDQ 603
            ...:| .|.:....::..:.::..|.:||..  :.|..:|.:||....|.:::|:       |:.
  Fly   573 SDDEDVKLRLCNQKIDDLEAERRDLMDQLRN--IKSKDISAKLAEERRKRLQLLE-------QEI 628

  Fly   604 TNLHNKLI--GEVMKISDQ----------------------------HSQAF------------- 625
            ::|..|||  ..::||.|:                            .|:.|
  Fly   629 SDLRRKLITQANLLKIRDKEREKIQNLSTEIRTMKESKVKLIRAMRGESEKFRQWKMVREKELTQ 693

  Fly   626 ----VAKLMEQMQQQQLLMSKEIQTNLQVIEENNQRHKAMLDSMQ---------EKFATIIDSSL 677
                ..|:..::.:||.|.||:.|...:..||....:|.:.|:::         .|:.....|:.
  Fly   694 LKSKDRKMQSEIVRQQTLHSKQRQVLKRKCEEALAANKRLKDALERQASAQAQRHKYKDNGGSAA 758

  Fly   678 QSVEEHAKQ---MHKKLEQLGAMSLPDAE-ELQNLQEELA---NERALAQQED------------ 723
            .|...:||.   :.::||.:  :||.||| .|:.|.|:.|   |...|.|||.
  Fly   759 GSSNANAKTDSWVDRELEII--LSLIDAEHSLEQLMEDRAVINNHYHLLQQEKTSDPAEAAEQAR 821

  Fly   724 ---ALLESMMMQMEQIKNLR----------------------------SKNSISMSVHLNKMEES 757
               :|.|.:.|:..||.:|:                            ||..:...|...:::.|
  Fly   822 ILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEGVQSLGESRTVSKQLLKTLVQQRRLQAS 886

  Fly   758 RLTRNH-RIDDIKSGIQDYQKLGIEASQSAQAELTSQMEAGMLCLDQGVANCSMLQVHMKNLNQK 821
            .|.... .:|::::.:.|.|:....||:..:. |.||.|..||.  |..|....:.|.::..||:
  Fly   887 SLNEQRTTLDELRAQLLDAQQQEDAASKRLRL-LQSQHEEQMLA--QQRAYEEKVSVLIRTANQR 948

  Fly   822 YEKETNENVGSVRVHHNQVEIICQESKQQLEAVQEKTEVNLEQMVDARQQLITEDRQRFIGHATV 886
            :                      .|::...|. |::.:: ||:::.:|:.|..|
  Fly   949 W----------------------AEARSPAED-QQRNQI-LEELLSSREALQQE----------- 978

  Fly   887 ATDLVQESNRQFSEHAEHQRQQL----QICE--QELVRFQQSELKTYAPTGTTPSKRDFVYPRTL 945
             .|.::..|:..|:..:.:.|.|    ||.:  :.:|....|:...:.|: |:.|||.....|.:
  Fly   979 -LDKLRAKNKSKSKAVKSEPQDLDDSFQIVDGNETVVLSDVSDDPDWVPS-TSKSKRIQSDSRNV 1041

  Fly   946 VATSPHQEIVRRYRQELDWSDLDTTATIDECSEGEHDVSMHSVQELSETETIMNSTPIEPVDG-- 1008
            :  ||.:      :|:.:.:.|..:             |:.|:...|.||           ||
  Fly  1042 I--SPPE------KQDANVTSLGNS-------------SIQSLNSTSATE-----------DGKR 1074

  Fly  1009 ---------VTVKRGCGTTRNSNS 1023
                     .|.|| ||....:|:
  Fly  1075 CKGCKCRTKCTTKR-CGCLSGNNA 1097

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	140/353 (40%)
		Kinesin	25..356	CDD:278646	133/337 (39%)
		Microtub_bind	923..>1009	CDD:290642	17/96 (18%)
Klp3A	NP_001284830.1	KISc_KIF4	7..336	CDD:276823	134/343 (39%)
		Kinesin	14..335	CDD:278646	133/337 (39%)
		Smc	<396..>994	CDD:224117	125/648 (19%)
		FlaC	522..633	CDD:225888	20/119 (17%)
		TCR	1075..1110	CDD:281618	6/24 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840