Protein Alignment Klp61F and Kif13a

DIOPT Version :9

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001100932.1
• Gene: Kif13a / 308173
• RGDID: 1307825
• Length: 1689
• Species: Rattus norvegicus
• Alignment Length: 1120
• Identity: 268/1120 - (23%)
• Similarity: 468/1120 - (41%)
• Gaps: 273/1120 - (24%)

  Fly    56 LDSKLTKKFTFDRSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAE 120
            :|...|.|:.     |.|.    |:..:...::|:...|||..:|||||||:||:.:|:|:  ||
  Rat     1 MDESNTTKYA-----GQEV----VFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH--AE 54

  Fly   121 LKSSWEDDSDIGIIPRALSHLFDELRMMEVE---YTMRISYLELYNEELCDLL---STDDTTKIR 179
                     .:|:|||....||..:.:.:.|   :.:.:||:|:|||::.|||   .:..:.|:|
  Rat    55 ---------QLGLIPRLCCALFQRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVR 110

  Fly   180 IFDDSTKKGSVIIQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVV----H 240
                ..|.....:.||.::.|.|.:|:..|:.:|.:.|..|.|.||.:|||||.||:|::    :
  Rat   111 ----EHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLY 171

  Fly   241 IRENGIEGEDMLKIGKLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVDRA-- 303
            ..::|..||   |:.|::||||||||.|||.| ..|.|::|..|||:||.|||.||::|.|:|
  Rat   172 DLQSGNSGE---KVSKVSLVDLAGSERVSKTG-AAGERLKEGSNINKSLTTLGLVISSLADQAAG 232

  Fly   304 ----PHVPYRESKLTRLLQESLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQ 364
                ..||||:|.||.||:::|||.::||:||||||...:.|||||||.||.|||.|.|...||:
  Rat   233 KGKNKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNE 297

  Fly   365 KLTKKTVLKEYTEEIDKLKRDLMAARDKNGIYLAEETYGEITLKLESQNRELNEKMLLLKA--LK 427
            ....| |::|..||::||:..|..|.                               .:||  ||
  Rat   298 DPNAK-VIRELREEVEKLREQLSQAE-------------------------------AMKAPELK 330

  Fly   428 DELQNKEKIFSEVSMSLVE---KTQELKKTEENLLNTKGTLLLTKKVLTKTKRRY-------KEK 482
            ::|:..||:..|::::..|   ||:|:.:..:..|.:.|..|.|..:.....:.|       ...
  Rat   331 EKLEESEKLIKELTVTWEEKLRKTEEIAQERQRQLESMGISLETSGIKVGDDKCYLVNLNADPAL 395

  Fly   483 KELVASHMKTE-QVLTTQAQEIL----------AAADLATDDTHQL----------HGTI----- 521
            .||:..::|.. :|....:|:|.          ...|:|||....|          :||:
  Rat   396 NELLVYYLKDHTRVGADTSQDIQLFGIGIQPEHCEIDIATDGDITLTPKENARSCVNGTLVCSVT 460

  Fly   522 -----ER---------RRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKEQLSQEMV 572
                 :|         |..|.::.||  |..||..::.        :..:....|..|..|:...
  Rat   461 QLWHGDRILWGNNHFFRINLPKRKRR--DWLKDFEKET--------SATEHDLDAASEASSEPDY 515

  Fly   573 NSSYVSQRL---ALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEVMKISDQHSQAFVAKLMEQMQ 634
            |..:....:   .|||:..::.:    .|.|:.|                     ::.:....::
  Rat   516 NYEFAQMEVIMKTLNSNDPVQNV----VQVLEKQ---------------------YLEEKRTALE 555

  Fly   635 QQQLLMSKEIQTNLQVIEENNQRHKAMLDSMQEKFATIIDSSLQSVEEHAKQMHKKLEQLGAMSL 699
            :|:|:..:|::...|.:....|..    .|..::.|....::.|.|.:.|::..:...|
  Rat   556 EQRLMYERELEQLRQQLSPERQPP----SSASDRLAYSSQTAQQKVTQWAEERDELFRQ------ 610

  Fly   700 PDAEELQNLQEELANERALAQQEDALLESM----------MMQMEQIKNLRSKNSISMSVHLNKM 754
                .|..|:|:|.....|.::.:.|.|.|          .:....:...|.:.:|.....:...
  Rat   611 ----SLAKLREQLVKANTLVREANFLAEEMGKLTDYQVTLQIPAANLSANRKRGAIVSEPAIQAR 671

  Fly   755 EESRLTRNHRIDDIKSGIQDYQKLGIEASQSAQAELTSQMEAGMLCLDQ--------------GV 805
            .:.:.|:...|:.:::.:.|.:.|..|..::..       :|..||..:              ||
  Rat   672 RKGKSTQVWTIEKLENKLIDMRDLYQEWKENVP-------KAKRLCGKRGDPFYEAQENHNLIGV 729

  Fly   806 AN-------CSM-LQVHMKNLNQKYEKETNENVGSVRVHHNQVEIICQESKQQ-------LEAVQ 855
            ||       |.: ||..:..::|:.|.....:|..:||.....|.:.::...:       ||.|.
  Rat   730 ANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVMRVTGTVPERVSEDDSSENSSESGSLEVVD 794

  Fly   856 EKTEVNLEQMVDARQQLITEDR-------QRFI---------GHATVATDLV-------QESNRQ 897
            ...|| :.::.....::|.::.       ..|:         ..:|||..:|       |..:.|
  Rat   795 SSGEV-IHRVKKLTCRVIIKEATGLPISLSNFVFCQYTFWDQYESTVAAPVVDPDVPSPQSKDAQ 858

  Fly   898 FSEHAEHQRQQLQICEQELVRFQQSELKTY-------APTGTTPSKRDFVYPRTLVATSPHQEIV 955
            ::....|.:..:....:|.:.|........       |..|:...:.|.::.:|........|:.
  Rat   859 YTVTFSHCKDYVVTVTEEFLEFISDGALAVEVWGHRCAGNGSPIWEVDSLHAKTRTLHDRWNEVT 923

  Fly   956 RR---YRQELDWSDLDTTATIDECSEGEHDVSMHSVQELSETETIMNSTPIEPVDG--------- 1008
            ||   :...|:.::|...|.: |..:.: ||:...|.:|.:..:......::||..
  Rat   924 RRIEMWISILELNELGDYAAV-ELHQAK-DVNTGGVFQLRQGHSRRVQVTVKPVQHSGTLPLMVE 986

  Fly  1009 --VTVKRGCGTTRNS 1021
              ::|..||.|.|::
  Rat   987 AILSVSIGCVTARST 1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	131/324 (40%)
		Kinesin	25..356	CDD:278646	127/315 (40%)
		Microtub_bind	923..>1009	CDD:290642	17/106 (16%)
Kif13a	NP_001100932.1	Motor_domain	3..296	CDD:277568	128/320 (40%)
		KISc	9..296	CDD:214526	126/314 (40%)
		Kinesin_assoc	293..405	CDD:292801	30/143 (21%)
		FHA	383..480	CDD:238017	16/96 (17%)
		KIF1B	685..729	CDD:289208	6/50 (12%)
		DUF3694	<1148..1207	CDD:289256

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000