Protein Alignment Klp61F and klp-11

DIOPT Version :9

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: NP_001369897.1
• Gene: klp-11 / 177685
• WormBaseID: WBGene00002222
• Length: 782
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 207/603 - (34%)
• Similarity: 321/603 - (53%)
• Gaps: 82/603 - (13%)

  Fly    14 KKSN--QNIQVYVRVRPLNSRERCIRSAEVV---------DVVGPREVVTRHTLDSKLTKKFTFD 67
            |||:  :.::|.||.|||:|:|.....:::|         ::..|:|       ..:.:|.||||
 Worm     6 KKSSKQETVKVIVRCRPLSSQEIANNYSKIVHMRPQRGQIELKNPKE-------QDEPSKDFTFD 63

  Fly    68 RSFGPESKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIG 132
            ..:...|.|.|:|......|::.||||||.|:||||||||||||||.|      |||  |....|
 Worm    64 AIYDENSTQSDLYEETFRDLVDSVLNGYNATIFAYGQTGTGKTHTMEG------KSS--DPEQRG 120

  Fly   133 IIPRALSHLFDELRMM-EVEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVIIQGLE 196
            :|.:.:.|:|:.:... ..||.:|.||||:|.|||.|||..:...|:.|  .....|.|.::.|.
 Worm   121 VIYKCIDHIFEHMAASHNQEYLVRASYLEIYQEELRDLLEAESNKKLEI--KERPDGGVYVKDLT 183

  Fly   197 EIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVHIRENGIEGEDMLKIGKLNLVD 261
            .....:..::::::.:|...|....|.||..|||||.:|.|.|.....|.:||..:.:|:|||||
 Worm   184 SKLTRTVGEIHEVMIRGNGHRSVGRTNMNEHSSRSHAIFIITVECSRIGEDGESHITVGRLNLVD 248

  Fly   262 LAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVD-RAPHVPYRESKLTRLLQESLGGRT 325
            |||||..||.| ..|.|.:|...||.||..||.||:|||| ::.|:|||:||||||||:||||.:
 Worm   249 LAGSERQSKTG-ATGERFKEATKINLSLSALGNVISALVDAKSAHIPYRDSKLTRLLQDSLGGNS 312

  Fly   326 KTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEIDKLKRDLMAAR 390
            ||.::|.|.|...:.||||.||.||:|||||:|:|::|:. .|..:|:|:.|||:.|:..|...:
 Worm   313 KTVMVACIGPASYNFEETLGTLRYANRAKNIKNQPKINED-PKDALLREFQEEIEMLREQLKQRK 376

  Fly   391 DKNGIYLAEETYGEITLKLESQNRELNEKMLLLKALKD----ELQNKEKIFSEVSMSLVEKTQ-E 450
            .::.....:..|.....|||.....:.:...|:|..||    |:|.|.        .|:||.: |
 Worm   377 TRSRDGATQSFYDAERAKLEDDIEAIQKDDSLIKHEKDRLIREIQEKH--------DLLEKERIE 433

  Fly   451 LKKTEENLLNTKGTLLLTK----KVLTKTKRRY----KEKKELVASHMKTEQVLTTQAQEILAAA 507
            ..:..|.:.|.:..|::..    ::.::||.::    |:::|| |...:.|       :|::.|.
 Worm   434 QARVAERIANIQSRLIVGSEEDGRLESRTKEQHAQLEKKRREL-AEQKRRE-------REMVEAL 490

  Fly   508 DLATDDTHQLHGTI-ERRRELDEKIRR------SCDQFKDRMQDNLEMIGGSLNLYQDQQAALKE 565
            :...:||..|..|. :.|.|::.|.::      ...|.::.::|    :.|:   |.|::..|.:
 Worm   491 ERQEEDTVDLKQTFSDLRTEVEAKTKKLKKMLIKLRQARNEIRD----VSGA---YSDERQDLDQ 548

  Fly   566 QLSQEMVNSSYVSQRLAL 583
            .:::       ||:.|.|
 Worm   549 TIAE-------VSKELKL 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	152/360 (42%)
		Kinesin	25..356	CDD:278646	145/341 (43%)
		Microtub_bind	923..>1009	CDD:290642
klp-11	NP_001369897.1	Motor_domain	12..343	CDD:419868	147/348 (42%)
		SMC_prok_B	337..>584	CDD:274008	61/254 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910