Protein Alignment Klp61F and LOC100490836

DIOPT Version :10

• Sequence 1: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Sequence 2: XP_002939901.2
• Gene: LOC100490836 / 100490836
• XenbaseID: XB-GENE-29080387
• Length: 687
• Species: Xenopus tropicalis
• Alignment Length: 762
• Identity: 220/762 - (28%)
• Similarity: 344/762 - (45%)
• Gaps: 166/762 - (21%)

  Fly    19 NIQVYVRVRPLNSRERCIRSAEVVDV-----------VGPREVVTRHTLDSKLTKKFTFDRSF-- 70
            |::|.|||||:|.||:...|..|:.:           |.|.||       .|..|:||||..|
 Frog     3 NVRVAVRVRPMNQREKEKHSVCVISMSQNKTILQSKAVSPGEV-------QKAPKEFTFDHCFWS 60

  Fly    71 ----GPE--SKQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDS 129
                .|:  :.|.:|:..:....||.:..|||..:|||||||:|||::|:|.           |.
 Frog    61 ADDSDPDTYAGQEEVFKTLEEGTIENIYQGYNVCIFAYGQTGSGKTYSMMGT-----------DD 114

  Fly   130 DIGIIPRALSHLFDELRMMEVEYTMRISYLELYNEELCDLLSTDDTTKIRIFDDSTKKGSVI--- 191
            :.|:|||....|.:  |..|....:.:||:|:|||::.|||....:.|    :.|.::.:::
 Frog   115 EPGLIPRFCRALLN--RKSEGTVRVELSYMEIYNEKVRDLLDLKKSKK----ELSVREHNILGPY 173

  Fly   192 IQGLEEIPVHSKDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSI-VVHIRENGIEGEDMLKIG 255
            ::||.:..|.:.:|:..||..|.:.|.||.|.||.:|||||.:|:: :..:..|...|.......
 Frog   174 VEGLSQHAVSTWEDIKLLLLAGNKCRTTAATKMNEESSRSHAIFTLTITQMFPNHESGTSKELHS 238

  Fly   256 KLNLVDLAGSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVD-RAPHVPYRESKLTRLLQE 319
            |.|||||||||..||.| .:|.::.|:.|||:||.:|||:|::|.: :..:|.||||.||.||:.
 Frog   239 KFNLVDLAGSEKASKTG-AQGKQLVESGNINKSLTSLGRIISSLTECKGSYVSYRESVLTWLLKN 302

  Fly   320 SLGGRTKTSIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEIDKLKR 384
            ||||.:||.::|||||...:..||.|||.||.|.:.|.|:.:||:. ||...:....||:.|||.
 Frog   303 SLGGNSKTVMLATISPAEDNYGETHSTLVYAERTRQIVNQAKVNED-TKCKAVATLQEEVQKLKE 366

  Fly   385 DLMAARDKNGIYLAEETYGEITLKLESQNRELNEKMLLLKALKDELQNKEKIFSEVSMSLVEKTQ 449
            .|..|:.:                   |:.||..|          |:..|.:..::::|..||
 Frog   367 QLKHAKSQ-------------------QSPELQSK----------LKESENLLKQLNLSWEEK-- 400

  Fly   450 ELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKK--ELVASHMKTEQVLTTQAQEILAAADLATD 512
             |||||||               .|..::|.|..  .:.||.:|.       |:|.....:|..|
 Frog   401 -LKKTEEN---------------AKVMQKYLESMGISVDASGIKC-------AKEQCCLVNLNPD 442

  Fly   513 ---DTHQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIG---------------GSLNLYQDQ 559
               :.:.|:...|.     .||.....|       :.::.|               |.:.|..:.
 Frog   443 PESNDYLLYYLTEH-----NKIGAGSSQ-------DFQLTGPGIEEEHCVITMTPDGDVFLVPNT 495

  Fly   560 QAALKEQLSQEMVNSSYVSQR----------LALNSSKSIEMLKEMCAQSLQDQTNLHNKLIGEV 614
            :|..|       ||.:.|.:|          |.||.|..:...|:....||.:     ||...|:
 Frog   496 KAETK-------VNGALVQERIRLYHEDKINLGLNYSFILNQSKKRQPNSLSE-----NKHEVEM 548

  Fly   615 MKISDQHSQAFVAK-------LMEQMQQQQLLMSK-EIQTNLQVIEENNQRHKAMLDSMQEKFAT 671
            .::|..|.....:.       |:...|.....::| .|....:.|...::.|.:...|..||...
 Frog   549 NEMSSDHKNKDESNPKQNPYYLLSGSQDDDTELTKTHINPKKEEISTESRSHDSFSTSSIEKVLA 613

  Fly   672 IIDSSLQSVEEHAKQMHKKLEQLGAMSLPDAEELQNLQEELANERAL 718
            |...||..::::...:.|||:....::..|:..|:|.::.:...:.|
 Frog   614 IPQESLLELQQNFTNLVKKLQSKQLITQQDSAGLENTEDMVLKSKTL 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	140/369 (38%)
		SMC_prok_B	<408..728	CDD:274008	71/349 (20%)
		SMC_prok_B	<651..>921	CDD:274008	15/68 (22%)
		Microtub_bind	923..>1004	CDD:464048
LOC100490836	XP_002939901.2	Motor_domain	2..346	CDD:473979	138/367 (38%)
		Kinesin_assoc	<376..455	CDD:465047	26/113 (23%)
		FHA	433..541	CDD:469597	23/126 (18%)
		DD	622..679	CDD:472698	7/39 (18%)