Protein Alignment galene and KCNK17

DIOPT Version :10

• Sequence 1: NP_612084.1
• Gene: galene / 38133
• FlyBaseID: FBgn0035192
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: NP_113648.2
• Gene: KCNK17 / 89822
• HGNCID: 14465
• Length: 332
• Species: Homo sapiens
• Alignment Length: 158
• Identity: 49/158 - (31%)
• Similarity: 74/158 - (46%)
• Gaps: 16/158 - (10%)

  Fly    33 KVLTCIV-SHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVLR 96
            :|..|.| |.|||:|..::|...|..:|..||.....:..|..|..:..|.:|...|...|
Human    13 RVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPA---- 73

  Fly    97 ESDWMANVSKHLANFEKQILTAIKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTD 161
                       |.:..:.::.|.|.............:|...||.|:|:..|||||||::||.|.
Human    74 -----------LDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTM 127

  Fly   162 WGKVTTIFYAIVGIPLMLICLSNIGDVM 189
            ..::..||:|:|||||.|:.|:.:|.:|
Human   128 AARLFCIFFALVGIPLNLVVLNRLGHLM 155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	115..189	CDD:462301	28/73 (38%)
		Ion_trans_2	626..706	CDD:462301
KCNK17	NP_113648.2	Ion_trans_2	81..157	CDD:462301	29/75 (39%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	116..121		4/4 (100%)
		Ion_trans_2	<206..268	CDD:462301
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	221..226
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..312