DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and Kcnk16

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001102990.1	Gene:	Kcnk16 / 688996	RGDID:	1582911	Length:	292	Species:	Rattus norvegicus

Alignment Length:	169	Identity:	52/169 - (30%)
Similarity:	86/169 - (50%)	Gaps:	27/169 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PQRGRCVAAICFSWKVLTCIVSHVLLVLLVVSYCVGGAYLFQHLERPHELEVKRDIQNLRVNLTE 83
            |:.|.|   .|:..:||..:::::..:||       ||.:||.||:..|.:.:...|..::...|
  Rat     2 PRAGVC---SCWGGQVLPLLLAYICYLLL-------GATIFQRLEKQAEAQSRDQFQLEKLRFLE 56

  Fly    84 NIWLLSDDAVVLRESDWMANVSKHLANFEKQILTA-IKADGWDGDEDLRKSQWTFAGSLFYSIIV 147
            |...|...|               |..|.:.||.| :|.....|: ....|.|.|..|.|::..|
  Rat    57 NYTCLDQQA---------------LEQFVQVILEAWVKGVNPKGN-STNPSNWDFGSSFFFAGTV 105

  Fly   148 ITTIGYGHISPRTDWGKVTTIFYAIVGIPLMLICLSNIG 186
            :||||||:::|.|:.|:|..:|||::||||.::.|:::|
  Rat   106 VTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNHLG 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	24/53 (45%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
Kcnk16	NP_001102990.1	Ion_trans_2	<92..148	CDD:285168	24/53 (45%)
Kcnk16	NP_001102990.1	Ion_trans_2	180..248	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9664
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	128	1.000	Inparanoid score	I4566
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960