Protein Alignment galene and Ork1

DIOPT Version :10

• Sequence 1: NP_612084.1
• Gene: galene / 38133
• FlyBaseID: FBgn0035192
• Length: 729
• Species: Drosophila melanogaster
• Sequence 2: XP_061504627.1
• Gene: Ork1 / 5667673
• VectorBaseID: AGAMI1_013932
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 788
• Identity: 160/788 - (20%)
• Similarity: 267/788 - (33%)
• Gaps: 268/788 - (34%)

  Fly    44 LVLLVVSYCVGGAYLFQHLERPHELEVKRDIQNL--RVNLTENI--WLLSDDAVVLRESDWMANV 104
            |:|...:|...||.:|.|:|  ::||.:|..:.|  |:.:.|.:  :|..:|..:.|:  .:..:
Mosquito     9 LLLFYAAYLFMGASVFYHVE--NDLETERRAEELAERIEINEMLVRYLSPEDMELQRK--LIGRL 69

  Fly   105 SKHLANFEKQILTAIKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIF 169
            .::..:         :...:..||......|.|..|.:::.|:.:|:|||:|||...:|::..||
Mosquito    70 DEYCGS---------RVTNYTEDEYEPPYVWDFYHSFYFAFIICSTVGYGNISPHNTFGRIFLIF 125

  Fly   170 YAIVGIPLMLICLSNIGDVMATSFRFLYWRICCYVCTRTAKRPRNA--RSRQRSMRSQRHARSQP 232
            ||::|:|:.....:.:|:..|..|..||.|...|      |...||  ..|:.|...|......|
Mosquito   126 YALIGLPVNGFFFAYVGEFWARGFVRLYRRYKAY------KLSANAGYAPRRISFIGQIVLYLIP 184

  Fly   233 -------PPS---------------FRRSMKMTQRSGND--SGLGPSMGHAYSDPDLRTM----- 268
                   .|:               :...:.:|.....|  :...||..|.:.  .|.|:
Mosquito   185 GVIVFIFAPACVFTYFEQWPYDVSVYYSFVTLTTIGFGDYAASFQPSQQHEFG--SLFTVYKIFI 247

  Fly   269 ------GRGYDDREFGHRSSGGGRNRRQQQQQHLHHDPRQ-RHTIYGD-----GYETQTLNR--- 318
                  |.||.....|..:.|....:.||.::.:..:.:: :|.::..     .|..:.||.
Mosquito   248 IFWFFAGIGYIFMILGFIAKGISHKKIQQLEKLVASNLKETQHRVWNGVTKDISYLRRILNEVYM 312

  Fly   319 ----------SNRYSSRQRQRD---------RMRDRHTVERER-YSRSHL--------DAGSI-- 353
                      |:|:.|..:.|.         |..::.|:.|:| .|.|.|        |.||:
Mosquito   313 LKFKPVYEEPSDRWLSLSKSRSSSCPELSMYRPPEQPTIRRKRANSESALVFAATRPVDGGSLVR 377

  Fly   354 -------------EDFG--DMQPPAKRAASVRSV--RSPHNQESSKASRELHRLHSA-------- 393
                         :.||  .:..||:..|.|.:.  ....||:.:::..|...|::.
Mosquito   378 RLSDTDLNRINREKTFGVQALVQPAELLARVVTALGNITANQDDNQSFLERASLNAGVNCFSDSQ 442

  Fly   394 -------------------------PGRSRAKSVD---PRHVSSHYEDVDE-------------- 416
                                     |.|.||.| |   |.|:||  :|.:|
Mosquito   443 ILASERTWSGWSMSGSDKSAYLTAPPMRPRAAS-DIGVPPHLSS--QDANEWTWSGGDNSQIQEI 504

  Fly   417 -----DVVRKTPIIPNRYALD---DFGGNRRQAAP------RSQSMPRSAHQRQRQ-KDRERERS 466
                 .|.:|..::  |.||.   :|..:.....|      ::.::.||..||... :.|.::.:
Mosquito   505 LQVRQKVKQKDNLL--RAALSNNVNFDSSLTINMPPTGRESKASAVNRSVLQRLNPFRKRSKQLA 567

  Fly   467 P----QPP-------------------PQSSYRQQHDRRAGSLGR---------QSSRYGN---H 496
            |    ..|                   |.|||.....|..||:..         :::..|:   .
Mosquito   568 PADIETAPGLDSYLAATGKGRSSMFNLPTSSYLSATSRGRGSILSMPPQDEHLLETTTIGDLLRA 632

  Fly   497 LELPDYDAPPPGRDHRRDRRG----------HSQGRYEDYVEESFDEG--------SLY------ 537
            |||...|....|....|...|          |..||::   .:.|..|        :|:
Mosquito   633 LELMHTDTVTAGAGQHRGSVGTGEPQAATLHHRAGRHQ---SQPFAGGASNLPSLLTLFTPPIEA 694

  Fly   538 -GDNNYEDYPP-ERHHSRSREPKRNRRRERAERLPP--------------SPR--IMSPMGFPVQ 584
             |.......|| .|..|....|...||.......||              ||.  |:.|...|::
Mosquito   695 GGSRRGSLKPPLGRTGSADSAPSVLRRPSFRPTNPPSYSATVSGSPAGGGSPTLGIIGPSPKPIR 759

  Fly   585 RQIRRRPS 592
            |:...|||
Mosquito   760 RRFSVRPS 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	115..189	CDD:462301	21/73 (29%)
		Ion_trans_2	626..706	CDD:462301
Ork1	XP_061504627.1	None