DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment galene and kcnk7

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001373286.1	Gene:	kcnk7 / 557297	ZFINID:	ZDB-GENE-110304-2	Length:	362	Species:	Danio rerio

Alignment Length:	153	Identity:	46/153 - (30%)
Similarity:	77/153 - (50%)	Gaps:	17/153 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KVLTCIVSHVLLVLLVV--SYCVGGAYLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVL 95
            |.||.:..|..:.|:|.  .:.|.||.:...||:|.|..:.::::.|:..      .|:|:..|.
Zfish     7 KALTFLRVHAFIFLMVAYGLFIVMGAVVLMVLEQPEENLLVQEVRELKAR------FLADNPCVE 65

  Fly    96 RESDWMANVSKHLANFEKQILTAIKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRT 160
            ..|  :..:...:.:..|:.:.|::|   |.||    ..:.|..|||:.|..:||.|||...|.:
Zfish    66 ERS--LDGLLMDVLSASKRGVAALQA---DSDE----CNFDFTSSLFFVITFLTTTGYGTTVPLS 121

  Fly   161 DWGKVTTIFYAIVGIPLMLICLS 183
            |.|:|..:.|.:|||||.::.||
Zfish   122 DEGRVFCVVYCLVGIPLTMLLLS 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	22/50 (44%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
kcnk7	NP_001373286.1	Ion_trans_2	<95..150	CDD:400301	22/50 (44%)
kcnk7	NP_001373286.1	Ion_trans_2	<203..>227	CDD:400301
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I10296
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000