DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment galene and Kcnk6

DIOPT Version :9

Sequence 1:	NP_612084.1	Gene:	galene / 38133	FlyBaseID:	FBgn0035192	Length:	729	Species:	Drosophila melanogaster
Sequence 2:	NP_001028697.2	Gene:	Kcnk6 / 52150	MGIID:	1891291	Length:	313	Species:	Mus musculus

Alignment Length:	141	Identity:	43/141 - (30%)
Similarity:	70/141 - (49%)	Gaps:	26/141 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 YCVGGAYLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVLRESDWMANVSKHLANFEKQI 115
            |...||.|...||||||..::.::..||..|             |:.|..:|  :..|..|.:::
Mouse    17 YLALGALLVARLERPHEARLRAELGTLREQL-------------LQHSPCVA--AHALDAFVERV 66

  Fly   116 LTA--------IKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFYAI 172
            |.|        ..|.|.....|   ..|.||.:||::..::||:|||:.:|.||.||..:|.:|:
Mouse    67 LAAGRLGRAALANASGAANASD---PAWDFASALFFASTLVTTVGYGYTTPLTDAGKAFSIVFAL 128

  Fly   173 VGIPLMLICLS 183
            :|:|:.::.|:
Mouse   129 LGVPITMLLLT 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
galene	NP_612084.1	Ion_trans_2	<134..189	CDD:285168	20/50 (40%)
		NESP55	341..586	CDD:115071
		Ion_trans	<621..709	CDD:278921
		Ion_trans_2	626..706	CDD:285168
Kcnk6	NP_001028697.2	Ion_trans_2	<91..146	CDD:285168	20/49 (41%)
		Ion_trans	<171..253	CDD:278921
		Ion_trans_2	180..259	CDD:285168
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	60	1.000	Domainoid score	I10523
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	130	1.000	Inparanoid score	I4619
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.860