DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment galene and kcnk6

DIOPT Version :9

Sequence 1:NP_612084.1 Gene:galene / 38133 FlyBaseID:FBgn0035192 Length:729 Species:Drosophila melanogaster
Sequence 2:NP_001025245.2 Gene:kcnk6 / 504083 ZFINID:ZDB-GENE-050309-213 Length:315 Species:Danio rerio


Alignment Length:139 Identity:40/139 - (28%)
Similarity:72/139 - (51%) Gaps:16/139 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 VLLVVSYCVGGAYLFQHLERPHELEVKRDIQNLRVNLTENIWLLSDDAVVLRESDWMANVSKHLA 109
            :|...:|.:.||.:|..:|||.|..:|.|:.:|:.... |:..::..|               |.
Zfish    15 ILAYFTYLLLGALVFSAIERPIEESLKADLSSLKAEFL-NLSCVNSTA---------------LE 63

  Fly   110 NFEKQILTAIKADGWDGDEDLRKSQWTFAGSLFYSIIVITTIGYGHISPRTDWGKVTTIFYAIVG 174
            .|.:::|.|.|......:....::.|..|.|||::..::||:||||.:|.:|.||..:|.||::|
Zfish    64 TFLERVLKANKYGVSVLENASLRTNWDLASSLFFANTMVTTVGYGHTTPLSDAGKAFSIVYALIG 128

  Fly   175 IPLMLICLS 183
            :|..::.|:
Zfish   129 VPFTMLVLT 137

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
galeneNP_612084.1 Ion_trans_2 <134..189 CDD:285168 21/50 (42%)
NESP55 341..586 CDD:115071
Ion_trans <621..709 CDD:278921
Ion_trans_2 626..706 CDD:285168
kcnk6NP_001025245.2 Ion_trans_2 84..145 CDD:285168 21/54 (39%)
Ion_trans_2 178..254 CDD:285168
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 62 1.000 Domainoid score I10296
eggNOG 1 0.900 - - E1_KOG1418
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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